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Ononis spinosa alleviated capsaicin-induced mechanical allodynia in a rat model through transient receptor potential vanilloid 1 modulation.
Jaffal SM, Al-Najjar BO, Abbas MA. Jaffal SM, et al. Korean J Pain. 2021 Jul 1;34(3):262-270. doi: 10.3344/kjp.2021.34.3.262. Korean J Pain. 2021. PMID: 34193633 Free PMC article.
It is well established that TRPV1 is involved in mechanical allodynia. This study investigates the effect of Ononis spinosa (Fabaceae) in CAPS-induced mechanical allodynia and its mechanism of action. ...O. spinosa decreased mechanical allodynia by 5.35-fold …
It is well established that TRPV1 is involved in mechanical allodynia. This study investigates the effect of Ononis spinosa (F …
Efficacy of extract from Ononis spinosa L. on ethanol-induced gastric ulcer in rats.
Manal Ahmad A, Yasser Ibrahim K, Manal Mohammad A. Manal Ahmad A, et al. J Tradit Chin Med. 2021 Apr;41(2):270-275. J Tradit Chin Med. 2021. PMID: 33825407 Free article.
OBJECTIVE: To investigate the efficacy of the extract from Ononis spinosa L. (O. spinosa) on ethanol-induced gastric ulcer in rats. METHODS: Phytochemical constituents of the extract from O. spinosa were analyzed using liquid chromatography-mass spectr …
OBJECTIVE: To investigate the efficacy of the extract from Ononis spinosa L. (O. spinosa) on ethanol-induced gastric ul …
Ononis spinosa L., an edible and medicinal plant: UHPLC-LTQ-Orbitrap/MS chemical profiling and biological activities of the herbal extract.
Stojković D , Drakulić D , Gašić U , Zengin G , Stevanović M , Rajčević N , Soković M . Stojković D , et al. Food Funct. 2020 Aug 1;11(8):7138-7151. doi: 10.1039/d0fo01595d. Epub 2020 Aug 4. Food Funct. 2020. PMID: 32749435
This study explored the chemical profile of the aerial parts of Ononis spinosa and further investigated its biological activities. ...
This study explored the chemical profile of the aerial parts of Ononis spinosa and further investigated its biological activit …
Aqueous Root Extract from Ononis spinosa Exerts Anti-adhesive Activity against Uropathogenic Escherichia coli.
Deipenbrock M, Sendker J, Hensel A. Deipenbrock M, et al. Planta Med. 2020 Mar;86(4):247-254. doi: 10.1055/a-1089-8645. Epub 2020 Jan 22. Planta Med. 2020. PMID: 31968378
Extracts from Ononis spinosa are traditionally used for urinary tract infections due to diuretic and anti-inflammatory activity. ...A hot water extract from the roots of O. spinosa (O. spinosa extract) was characterized by LC-qTOF-MS. The influence of …
Extracts from Ononis spinosa are traditionally used for urinary tract infections due to diuretic and anti-inflammatory activit …
Qualitative and Quantitative Phytochemical Analysis of Ononis Hairy Root Cultures.
Gampe N, Szakács Z, Darcsi A, Boldizsár I, Szőke É, Kuzovkina I, Kursinszki L, Béni S. Gampe N, et al. Front Plant Sci. 2021 Jan 13;11:622585. doi: 10.3389/fpls.2020.622585. eCollection 2020. Front Plant Sci. 2021. PMID: 33584762 Free PMC article.
Besides isoflavones, less prevalent isoflavones and pterocarpans with valuable biological effects can be found in Ononis species as well. As these plants are only collected but not cultivated, biotechnological methods could play a role in the larger-scale extraction of …
Besides isoflavones, less prevalent isoflavones and pterocarpans with valuable biological effects can be found in Ononis species as w …
Root Extracts From Ononis spinosa Inhibit IL-8 Release via Interactions With Toll-Like Receptor 4 and Lipopolysaccharide.
Spiegler V, Gierlikowska B, Saenger T, Addotey JN, Sendker J, Jose J, Kiss AK, Hensel A. Spiegler V, et al. Front Pharmacol. 2020 Jun 12;11:889. doi: 10.3389/fphar.2020.00889. eCollection 2020. Front Pharmacol. 2020. PMID: 32595508 Free PMC article.
Extracts from the roots of Ononis spinosa L. (restharrow roots) are traditionally used for the treatment of patients with urinary tract infections due to its mild diuretic activity, caused by the inhibition of renal human hyaluronidase-1 by isoflavonoids. ...This st …
Extracts from the roots of Ononis spinosa L. (restharrow roots) are traditionally used for the treatment of patients with urin …
Methanolic Extract of the Herb Ononis spinosa L. Is an Antifungal Agent with no Cytotoxicity to Primary Human Cells.
Stojković D, Dias MI, Drakulić D, Barros L, Stevanović M, C F R Ferreira I, D Soković M. Stojković D, et al. Pharmaceuticals (Basel). 2020 Apr 24;13(4):78. doi: 10.3390/ph13040078. Pharmaceuticals (Basel). 2020. PMID: 32344670 Free PMC article.
Ononis spinosa L. is a plant traditionally used as folk remedy. There are numerous studies regarding chemical constituents and health beneficial properties of Ononidis Radix. The following study was designed to investigate chemical composition and antifungal potenti …
Ononis spinosa L. is a plant traditionally used as folk remedy. There are numerous studies regarding chemical constituents and …
A new cyclic polyketide and other constituents from Ononis spinosa growing wildly in Jordan and their antioxidant activity.
Abu Zarga MH, Al-Jaber HI, Al-Qudah MA, Al-Aboudi AMF. Abu Zarga MH, et al. J Asian Nat Prod Res. 2022 Mar;24(3):290-295. doi: 10.1080/10286020.2021.1914597. Epub 2021 Apr 21. J Asian Nat Prod Res. 2022. PMID: 33881372
The new cyclic polyketide 7,9,11-trihydroxytetracos-2-eneoic acid delta-lactone (1), together with other eleven known compounds, were isolated from Ononis spinosa, growing wildly in Jordan. All isolated compounds were identified by thorough investigation of their sp …
The new cyclic polyketide 7,9,11-trihydroxytetracos-2-eneoic acid delta-lactone (1), together with other eleven known compounds, were isolat …
Quantitative determination of isoflavonoids in Ononis species by UPLC-UV-DAD.
Gampe N, Nagy E, Kursinszki L, Béni S. Gampe N, et al. Phytochem Anal. 2021 Jul;32(4):474-481. doi: 10.1002/pca.2995. Epub 2020 Sep 14. Phytochem Anal. 2021. PMID: 32929804
INTRODUCTION: The root of the Ononis species has been used internally and externally in ethnomedicine for centuries and contains biologically valuable isoflavonoid compounds. ...OBJECTIVES: In this article we aimed to develop an optimised sample preparation protocol alongs …
INTRODUCTION: The root of the Ononis species has been used internally and externally in ethnomedicine for centuries and contains biol …
Using principle component analysis to compare genetic diversity across polyploidy levels within plant complexes: an example from British Restharrows (Ononis spinosa and Ononis repens).
Kloda JM, Dean PD, Maddren C, MacDonald DW, Mayes S. Kloda JM, et al. Heredity (Edinb). 2008 Mar;100(3):253-60. doi: 10.1038/sj.hdy.6801044. Epub 2007 Dec 12. Heredity (Edinb). 2008. PMID: 18073784
We have investigated the use of principle component (PCO) analysis as one approach to elucidate population structure within British Restharrows (Leguminsoae, Ononis spp). Restharrows were common agricultural weed species until the advent of mechanical ploughing and both di …
We have investigated the use of principle component (PCO) analysis as one approach to elucidate population structure within British Restharr …
49 results