Prolonged activation of EP3 receptor-expressing preoptic neurons underlies torpor responses.
Machado NLS, Raffin F, Kaur S, Banks AS, Lynch N, Fanari O, Plascencia OR, Aten S, Lima JD, Bandaru SS, Palmiter RD, Arrigoni E, Saper CB.
Machado NLS, et al.
Res Sq [Preprint]. 2023 May 2:rs.3.rs-2861253. doi: 10.21203/rs.3.rs-2861253/v1.
Res Sq. 2023.
PMID: 37205518
Free PMC article.
Preprint.
Many species use a temporary drop in body temperature and metabolic rate (torpor) as a strategy to survive food scarcity. ...These MnPO(EP3R) neurons produce persistent fever responses when inhibited and prolonged hypothermic responses when activated either chemo- or op …
Many species use a temporary drop in body temperature and metabolic rate (torpor) as a strategy to survive food scarcity. ...These Mn …