Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1912 1
1922 2
1927 1
1945 1
1948 2
1949 1
1951 2
1952 2
1953 2
1955 1
1958 1
1959 4
1960 1
1961 2
1962 3
1963 2
1964 2
1965 6
1966 3
1967 2
1968 9
1969 2
1971 2
1974 2
1975 7
1976 6
1977 7
1978 8
1979 9
1980 9
1981 14
1982 6
1983 15
1984 15
1985 8
1986 4
1987 10
1988 5
1989 6
1990 14
1991 7
1992 12
1993 4
1994 9
1995 4
1996 8
1997 5
1998 12
1999 4
2000 6
2001 7
2002 4
2003 8
2004 4
2005 6
2006 5
2007 3
2008 4
2009 10
2010 6
2011 6
2012 7
2013 5
2014 8
2015 8
2016 15
2017 19
2018 23
2019 36
2020 46
2021 66
2022 51
2023 56
2024 24

Text availability

Article attribute

Article type

Publication date

Search Results

656 results

Results by year

Filters applied: . Clear all
Page 1
Did you mean organotrophic (406 results)?
Tumour exosome integrins determine organotropic metastasis.
Hoshino A, Costa-Silva B, Shen TL, Rodrigues G, Hashimoto A, Tesic Mark M, Molina H, Kohsaka S, Di Giannatale A, Ceder S, Singh S, Williams C, Soplop N, Uryu K, Pharmer L, King T, Bojmar L, Davies AE, Ararso Y, Zhang T, Zhang H, Hernandez J, Weiss JM, Dumont-Cole VD, Kramer K, Wexler LH, Narendran A, Schwartz GK, Healey JH, Sandstrom P, Labori KJ, Kure EH, Grandgenett PM, Hollingsworth MA, de Sousa M, Kaur S, Jain M, Mallya K, Batra SK, Jarnagin WR, Brady MS, Fodstad O, Muller V, Pantel K, Minn AJ, Bissell MJ, Garcia BA, Kang Y, Rajasekhar VK, Ghajar CM, Matei I, Peinado H, Bromberg J, Lyden D. Hoshino A, et al. Nature. 2015 Nov 19;527(7578):329-35. doi: 10.1038/nature15756. Epub 2015 Oct 28. Nature. 2015. PMID: 26524530 Free PMC article.
Ever since Stephen Paget's 1889 hypothesis, metastatic organotropism has remained one of cancer's greatest mysteries. Here we demonstrate that exosomes from mouse and human lung-, liver- and brain-tropic tumour cells fuse preferentially with resident cells at their predict …
Ever since Stephen Paget's 1889 hypothesis, metastatic organotropism has remained one of cancer's greatest mysteries. Here we demonst …
Extracellular vesicle-associated organotropic metastasis.
Mo Z, Cheong JYA, Xiang L, Le MTN, Grimson A, Zhang DX. Mo Z, et al. Cell Prolif. 2021 Jan;54(1):e12948. doi: 10.1111/cpr.12948. Epub 2020 Nov 3. Cell Prolif. 2021. PMID: 33145869 Free PMC article. Review.
Here, we review and summarize recent findings regarding EV-associated organotropic metastasis as well as some of the general mechanisms by which EVs contribute to this important process in cancer and provide a future perspective on this emerging topic. ...Further investiga …
Here, we review and summarize recent findings regarding EV-associated organotropic metastasis as well as some of the general mechanis …
Characteristics and Significance of the Pre-metastatic Niche.
Liu Y, Cao X. Liu Y, et al. Cancer Cell. 2016 Nov 14;30(5):668-681. doi: 10.1016/j.ccell.2016.09.011. Cancer Cell. 2016. PMID: 27846389 Free article. Review.
We propose six characteristics that define the pre-metastatic niche, which enable tumor cell colonization and promote metastasis, including immunosuppression, inflammation, angiogenesis/vascular permeability, lymphangiogenesis, organotropism, and reprogramming. We highligh …
We propose six characteristics that define the pre-metastatic niche, which enable tumor cell colonization and promote metastasis, including …
Exosome-Mediated Metastasis: Communication from a Distance.
Wortzel I, Dror S, Kenific CM, Lyden D. Wortzel I, et al. Dev Cell. 2019 May 6;49(3):347-360. doi: 10.1016/j.devcel.2019.04.011. Dev Cell. 2019. PMID: 31063754 Free article. Review.
Here, we review work on the contribution of exosome cargo to cancer progression, the role of exosomes in PMN establishment, and the function of exosomes in organotropic metastasis. We also describe the clinical utility of exosomes....
Here, we review work on the contribution of exosome cargo to cancer progression, the role of exosomes in PMN establishment, and the function …
Immune determinants of the pre-metastatic niche.
Patras L, Shaashua L, Matei I, Lyden D. Patras L, et al. Cancer Cell. 2023 Mar 13;41(3):546-572. doi: 10.1016/j.ccell.2023.02.018. Cancer Cell. 2023. PMID: 36917952 Free PMC article. Review.
Primary tumors actively and specifically prime pre-metastatic niches (PMNs), the future sites of organotropic metastasis, preparing these distant microenvironments for disseminated tumor cell arrival. ...
Primary tumors actively and specifically prime pre-metastatic niches (PMNs), the future sites of organotropic metastasis, preparing t …
Organotropic Targeting of Biomimetic Nanoparticles to Treat Lung Disease.
Holay M, Zhou J, Park JH, Landa I, Ventura CJ, Gao W, Fang RH, Zhang L. Holay M, et al. Bioconjug Chem. 2022 Apr 20;33(4):586-593. doi: 10.1021/acs.bioconjchem.1c00599. Epub 2022 Mar 14. Bioconjug Chem. 2022. PMID: 35285617
In particular, the advent of cell membrane coating nanotechnology has enabled researchers to leverage the inherent tropisms displayed by living cells, bypassing many of the challenges associated with traditional bottom-up nanoengineering. In this work, we report on a biomimetic …
In particular, the advent of cell membrane coating nanotechnology has enabled researchers to leverage the inherent tropisms displayed by liv …
Genomic mapping of metastatic organotropism in lung adenocarcinoma.
Lengel HB, Mastrogiacomo B, Connolly JG, Tan KS, Liu Y, Fick CN, Dunne EG, He D, Lankadasari MB, Satravada BA, Sun Y, Kundra R, Fong C, Smith S, Riely GJ, Rudin CM, Gomez DR, Solit DB, Berger MF, Li BT, Mayo MW, Matei I, Lyden DC, Adusumilli PS, Schultz N, Sanchez-Vega F, Jones DR. Lengel HB, et al. Cancer Cell. 2023 May 8;41(5):970-985.e3. doi: 10.1016/j.ccell.2023.03.018. Epub 2023 Apr 20. Cancer Cell. 2023. PMID: 37084736 Free PMC article.
We analyzed 2,532 lung adenocarcinomas (LUAD) to identify the clinicopathological and genomic features associated with metastasis, metastatic burden, organotropism, and metastasis-free survival. Patients who develop metastasis are younger and male, with primary tumors enri …
We analyzed 2,532 lung adenocarcinomas (LUAD) to identify the clinicopathological and genomic features associated with metastasis, metastati …
656 results

Searches related to "organotropic"