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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 3
1946 16
1947 19
1948 23
1949 19
1950 12
1951 11
1952 17
1953 15
1954 4
1955 38
1956 52
1957 158
1958 106
1959 82
1960 101
1961 99
1962 120
1963 183
1964 178
1965 164
1966 178
1967 232
1968 265
1969 282
1970 357
1971 291
1972 244
1973 257
1974 250
1975 229
1976 204
1977 214
1978 222
1979 283
1980 291
1981 321
1982 299
1983 379
1984 405
1985 463
1986 481
1987 553
1988 635
1989 774
1990 774
1991 866
1992 803
1993 877
1994 882
1995 899
1996 854
1997 845
1998 869
1999 936
2000 967
2001 1012
2002 952
2003 1047
2004 1010
2005 1071
2006 1090
2007 1130
2008 1138
2009 1136
2010 1138
2011 1239
2012 1344
2013 1306
2014 1219
2015 1223
2016 1154
2017 1068
2018 1038
2019 1021
2020 1061
2021 959
2022 826
2023 633
2024 251

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41,406 results

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Page 1
Oxazole-Based Compounds As Anticancer Agents.
Chiacchio MA, Lanza G, Chiacchio U, Giofrè SV, Romeo R, Iannazzo D, Legnani L. Chiacchio MA, et al. Curr Med Chem. 2019;26(41):7337-7371. doi: 10.2174/0929867326666181203130402. Curr Med Chem. 2019. PMID: 30501590 Review.
Heterocyclic compounds represent a significant target for anti-cancer research and drug discovery, due to their structural and chemical diversity. Oxazoles, with oxygen and nitrogen atoms present in the core structure, enable various types of interactions with different en …
Heterocyclic compounds represent a significant target for anti-cancer research and drug discovery, due to their structural and chemical dive …
Naturally Occurring Oxazole-Containing Peptides.
Mhlongo JT, Brasil E, de la Torre BG, Albericio F. Mhlongo JT, et al. Mar Drugs. 2020 Apr 10;18(4):203. doi: 10.3390/md18040203. Mar Drugs. 2020. PMID: 32290087 Free PMC article. Review.
Oxazole-containing peptides are mostly of marine origin and they form an intriguing family with a broad range of biological activities. ...
Oxazole-containing peptides are mostly of marine origin and they form an intriguing family with a broad range of biological activitie …
Evaluation of 2,3-dihydroimidazo[2,1-b]oxazole and imidazo[2,1-b]oxazole derivatives as chemotherapeutic agents.
Shahin AI, Zaraei SO, Alzuraiqi S, Abdulateef Z, Abbas NE, Al-Tel TH, El-Gamal MI. Shahin AI, et al. Future Med Chem. 2023 Oct;15(20):1885-1901. doi: 10.4155/fmc-2023-0147. Epub 2023 Oct 10. Future Med Chem. 2023. PMID: 37814826 Review.
Imidazo[2,1-b]oxazole and 2,3-dihydroimidazo[2,1-b]oxazole ring systems are commonly employed in therapeutically active molecules. ...
Imidazo[2,1-b]oxazole and 2,3-dihydroimidazo[2,1-b]oxazole ring systems are commonly employed in therapeutically active molecu …
Recent advance in oxazole-based medicinal chemistry.
Zhang HZ, Zhao ZL, Zhou CH. Zhang HZ, et al. Eur J Med Chem. 2018 Jan 20;144:444-492. doi: 10.1016/j.ejmech.2017.12.044. Epub 2017 Dec 14. Eur J Med Chem. 2018. PMID: 29288945 Review.
The related researches in oxazole-based derivatives including oxazoles, isoxazoles, oxazolines, oxadiazoles, oxazolidones, benzoxazoles and so on, as medicinal drugs have been an extremely active topic, and numerous excellent achievements have been acquired. ...The …
The related researches in oxazole-based derivatives including oxazoles, isoxazoles, oxazolines, oxadiazoles, oxazolidones, ben …
Recent Developments in Oxazole Derivatives as Anticancer Agents: Review on Synthetic Strategies, Mechanism of Action and SAR Studies.
Kulkarni S, Kaur K, Jaitak V. Kulkarni S, et al. Anticancer Agents Med Chem. 2022;22(10):1859-1882. doi: 10.2174/1871520621666210915095421. Anticancer Agents Med Chem. 2022. PMID: 34525925 Review.
Oxazoles also inhibit tubulin protein to induce apoptosis in cancer cells. ...CONCLUSION: Oxazole is a five-membered heterocycle, with oxygen and nitrogen at 1 and 3 positions, respectively. ...
Oxazoles also inhibit tubulin protein to induce apoptosis in cancer cells. ...CONCLUSION: Oxazole is a five-membered heterocyc …
Muscarine, imidazole, oxazole and thiazole alkaloids.
Jin Z. Jin Z. Nat Prod Rep. 2016 Oct 26;33(11):1268-1317. doi: 10.1039/c6np00067c. Nat Prod Rep. 2016. PMID: 27714029 Review.
Rep., 2013, 30, 869-915The structurally diverse imidazole-, oxazole-, and thiazole-containing secondary metabolites are widely distributed in terrestrial and marine environments, and exhibit extensive pharmacological activities. ...
Rep., 2013, 30, 869-915The structurally diverse imidazole-, oxazole-, and thiazole-containing secondary metabolites are widely distri …
Recent Advances in the Synthesis of Oxazole-Based Molecules via van Leusen Oxazole Synthesis.
Zheng X, Liu W, Zhang D. Zheng X, et al. Molecules. 2020 Mar 31;25(7):1594. doi: 10.3390/molecules25071594. Molecules. 2020. PMID: 32244317 Free PMC article. Review.
Oxazole compounds, including one nitrogen atom and one oxygen atom in a five-membered heterocyclic ring, are present in various biological activities. ...The van Leusen reaction, based on tosylmethylisocyanides (TosMICs), is one of the most appropriate strategies to prepar …
Oxazole compounds, including one nitrogen atom and one oxygen atom in a five-membered heterocyclic ring, are present in various biolo …
Antiproliferative activity of thiazole and oxazole derivatives: A systematic review of in vitro and in vivo studies.
Guerrero-Pepinosa NY, Cardona-Trujillo MC, Garzón-Castaño SC, Veloza LA, Sepúlveda-Arias JC. Guerrero-Pepinosa NY, et al. Biomed Pharmacother. 2021 Jun;138:111495. doi: 10.1016/j.biopha.2021.111495. Epub 2021 Mar 23. Biomed Pharmacother. 2021. PMID: 33765586 Free article. Review.
Thiazole and oxazole are compounds with a heterocyclic nucleus that have attracted the attention of medicinal chemistry due to the great variety of biological activities that they enable. ...This systematic review provides evidence from the literature on the antiproliferat …
Thiazole and oxazole are compounds with a heterocyclic nucleus that have attracted the attention of medicinal chemistry due to the gr …
Current Scenario of 1,3-oxazole Derivatives for Anticancer Activity.
Yan X, Wen J, Zhou L, Fan L, Wang X, Xu Z. Yan X, et al. Curr Top Med Chem. 2020;20(21):1916-1937. doi: 10.2174/1568026620666200624161151. Curr Top Med Chem. 2020. PMID: 32579505 Review.
Thus, the 1,3-oxazole moiety is a useful template for the development of novel anticancer agents. This review will provide a comprehensive overview of the recent advances on 1,3-oxazole derivatives with potential therapeutic applications as anticancer agents, focus …
Thus, the 1,3-oxazole moiety is a useful template for the development of novel anticancer agents. This review will provide a comprehe …
Imidazole, oxazole and thiazole alkaloids.
Jin Z. Jin Z. Nat Prod Rep. 2006 Jun;23(3):464-96. doi: 10.1039/b502166a. Epub 2006 Mar 28. Nat Prod Rep. 2006. PMID: 16741589 Review. No abstract available.
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