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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 2
2000 4
2001 4
2002 3
2003 2
2004 1
2005 5
2006 6
2007 8
2008 7
2009 7
2010 5
2011 12
2012 19
2013 31
2014 31
2015 25
2016 28
2017 26
2018 22
2019 31
2020 23
2021 26
2022 35
2023 16
2024 13

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341 results

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Page 1
Efficacy of Palmitoylethanolamide for Pain: A Meta-Analysis.
Artukoglu BB, Beyer C, Zuloff-Shani A, Brener E, Bloch MH. Artukoglu BB, et al. Pain Physician. 2017 Jul;20(5):353-362. Pain Physician. 2017. PMID: 28727699 Free article. Review.
SETTING: This meta-analysis examined all randomized, controlled trials involving the effect of PEA on pain score. METHODS: We searched PubMed and Embase for randomized, active or placebo-controlled trials of PEA for the treatment of acute or chronic pain. ...KEY WOR …
SETTING: This meta-analysis examined all randomized, controlled trials involving the effect of PEA on pain score. METHODS: We searche …
Palmitoylethanolamide in the Treatment of Chronic Pain: A Systematic Review and Meta-Analysis of Double-Blind Randomized Controlled Trials.
Lang-Illievich K, Klivinyi C, Lasser C, Brenna CTA, Szilagyi IS, Bornemann-Cimenti H. Lang-Illievich K, et al. Nutrients. 2023 Mar 10;15(6):1350. doi: 10.3390/nu15061350. Nutrients. 2023. PMID: 36986081 Free PMC article. Review.
Chronic pain is a major source of morbidity for which there are limited effective treatments. Palmitoylethanolamide (PEA), a naturally occurring fatty acid amide, has demonstrated utility in the treatment of neuropathic and inflammatory pain. ...
Chronic pain is a major source of morbidity for which there are limited effective treatments. Palmitoylethanolamide (PEA), a n …
Palmitoylethanolamide: A Natural Compound for Health Management.
Clayton P, Hill M, Bogoda N, Subah S, Venkatesh R. Clayton P, et al. Int J Mol Sci. 2021 May 18;22(10):5305. doi: 10.3390/ijms22105305. Int J Mol Sci. 2021. PMID: 34069940 Free PMC article. Review.
Dietary supplementation is a valid strategy to reduce the risk and severity of such disorders. Palmitoylethanolamide (PEA) is an endocannabinoid-like lipid mediator with extensively documented anti-inflammatory, analgesic, antimicrobial, immunomodulatory and neuroprotectiv …
Dietary supplementation is a valid strategy to reduce the risk and severity of such disorders. Palmitoylethanolamide (PEA) is an endo …
Chronic Pain in Dogs and Cats: Is There Place for Dietary Intervention with Micro-Palmitoylethanolamide?
Della Rocca G, Gamba D. Della Rocca G, et al. Animals (Basel). 2021 Mar 29;11(4):952. doi: 10.3390/ani11040952. Animals (Basel). 2021. PMID: 33805489 Free PMC article. Review.
In the present paper, the role of non-neuronal cells in pain signaling is discussed and a large number of studies on the effect of palmitoylethanolamide in inflammatory and neuropathic chronic pain are reviewed. Overall, available evidence suggests that there …
In the present paper, the role of non-neuronal cells in pain signaling is discussed and a large number of studies on the effect of …
Orofacial Pain Management: An Overview of the Potential Benefits of Palmitoylethanolamide and Other Natural Agents.
Santonocito S, Donzella M, Venezia P, Nicolosi G, Mauceri R, Isola G. Santonocito S, et al. Pharmaceutics. 2023 Apr 9;15(4):1193. doi: 10.3390/pharmaceutics15041193. Pharmaceutics. 2023. PMID: 37111679 Free PMC article. Review.
The success of therapy depends on the reduction in and management of pain through specific drugs, hence the need to analyze new pain medications with specific activity, which are suitable for long-term use, with a low risk of side effects and interactions with other …
The success of therapy depends on the reduction in and management of pain through specific drugs, hence the need to analyze new pa …
Clinical applications of palmitoylethanolamide in pain management: protocol for a scoping review.
Passavanti MB, Alfieri A, Pace MC, Pota V, Sansone P, Piccinno G, Barbarisi M, Aurilio C, Fiore M. Passavanti MB, et al. Syst Rev. 2019 Jan 8;8(1):9. doi: 10.1186/s13643-018-0934-z. Syst Rev. 2019. PMID: 30621775 Free PMC article. Review.
BACKGROUND: Palmitoylethanolamide (PEA) belong to endocannabinoid family, a group of fatty acid amides. ...The Outcomes will be the reduction of pain not restricted to specific scales laying out the pain outcome data described in the included studies. ...
BACKGROUND: Palmitoylethanolamide (PEA) belong to endocannabinoid family, a group of fatty acid amides. ...The Outcomes will be the r …
The Basal Pharmacology of Palmitoylethanolamide.
Rankin L, Fowler CJ. Rankin L, et al. Int J Mol Sci. 2020 Oct 26;21(21):7942. doi: 10.3390/ijms21217942. Int J Mol Sci. 2020. PMID: 33114698 Free PMC article. Review.
Palmitoylethanolamide (PEA, N-hexadecanoylethanolamide) is an endogenous compound belonging to the family of N-acylethanolamines. ...Given the potential clinical utility of PEA, not least for the treatment of pain where there is a clear need for new well-tolerated d …
Palmitoylethanolamide (PEA, N-hexadecanoylethanolamide) is an endogenous compound belonging to the family of N-acylethanolamines. ... …
Micronized palmitoylethanolamide/trans-polydatin treatment of endometriosis-related pain: a meta-analysis.
Indraccolo U, Indraccolo SR, Mignini F. Indraccolo U, et al. Ann Ist Super Sanita. 2017 Apr-Jun;53(2):125-134. doi: 10.4415/ANN_17_02_08. Ann Ist Super Sanita. 2017. PMID: 28617258 Free article. Review.
AIM: To demonstrate clinical effectiveness of micronized palmitoylethanolamide-trans-polydatin combination in reducing endometriotic chronic pelvic pain. ...RESULTS: Four studies of poor quality were available. In a heterogeneous sample of endometriotic patients wit …
AIM: To demonstrate clinical effectiveness of micronized palmitoylethanolamide-trans-polydatin combination in reducing endometriotic …
ALIAmides Update: Palmitoylethanolamide and Its Formulations on Management of Peripheral Neuropathic Pain.
D'Amico R, Impellizzeri D, Cuzzocrea S, Di Paola R. D'Amico R, et al. Int J Mol Sci. 2020 Jul 27;21(15):5330. doi: 10.3390/ijms21155330. Int J Mol Sci. 2020. PMID: 32727084 Free PMC article. Review.
The aim of this review is to discuss a novel approach on neuropathic pain management, which is based on the knowledge of processes that underlie the development of peripheral neuropathic pain; in particular highlights the role of glia and mast cells in pain a …
The aim of this review is to discuss a novel approach on neuropathic pain management, which is based on the knowledge of processes th …
Effects of Palmitoylethanolamide (PEA) on Nociceptive, Musculoskeletal and Neuropathic Pain: Systematic Review and Meta-Analysis of Clinical Evidence.
Scuteri D, Guida F, Boccella S, Palazzo E, Maione S, Rodríguez-Landa JF, Martínez-Mota L, Tonin P, Bagetta G, Corasaniti MT. Scuteri D, et al. Pharmaceutics. 2022 Aug 11;14(8):1672. doi: 10.3390/pharmaceutics14081672. Pharmaceutics. 2022. PMID: 36015298 Free PMC article. Review.
Palmitoylethanolamide (PEA) has been demonstrated to improve pain in preclinical contexts, but an appraisal of clinical evidence is still lacking. ...The primary outcome was pain reduction, as measured by a pain assessment scale. The secondary outcome …
Palmitoylethanolamide (PEA) has been demonstrated to improve pain in preclinical contexts, but an appraisal of clinical eviden …
341 results