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Showing results for paracetamol q genetics
Your search for paracetamol-q-generics retrieved no results
Genetic Association of Single Nucleotide Polymorphisms with Acetaminophen-Induced Hepatotoxicity.
Heruth DP, Shortt K, Zhang N, Li DY, Zhang LQ, Qing Ye S. Heruth DP, et al. J Pharmacol Exp Ther. 2018 Oct;367(1):95-100. doi: 10.1124/jpet.118.248583. Epub 2018 Aug 3. J Pharmacol Exp Ther. 2018. PMID: 30076262 Review.
Individual variability in the response to both therapeutic and toxic levels of acetaminophen suggests a genetic component is involved in acetaminophen metabolism. In this review, we evaluate the genetic association studies that have identified 147 sing …
Individual variability in the response to both therapeutic and toxic levels of acetaminophen suggests a genetic component is i …
Macrophage-Inducible C-Type Lectin Signaling Exacerbates Acetaminophen-Induced Liver Injury by Promoting Kupffer Cell Activation in Mice.
Zhao J, Kim JW, Zhou Z, Qi J, Tian W, Lim CW, Han KM, Kim B. Zhao J, et al. Mol Pharmacol. 2021 Feb;99(2):92-103. doi: 10.1124/molpharm.120.000043. Epub 2020 Dec 1. Mol Pharmacol. 2021. PMID: 33262251
Overdose of acetaminophen (APAP) has become one of the most frequent causes of acute liver failure. ...Collectively, Mincle can regulate the inflammatory response of KCs, which is necessary for the complete progression of hepatotoxicity induced by APAP. SIGNIFICANCE STATEM …
Overdose of acetaminophen (APAP) has become one of the most frequent causes of acute liver failure. ...Collectively, Mincle can regul …
Multiomics Profiling Reveals Protective Function of Schisandra Lignans against Acetaminophen-Induced Hepatotoxicity.
Yan C, Guo H, Ding Q, Shao Y, Kang D, Yu T, Li C, Huang H, Du Y, Wang H, Hu K, Xie L, Wang G, Liang Y. Yan C, et al. Drug Metab Dispos. 2020 Oct;48(10):1092-1103. doi: 10.1124/dmd.120.000083. Epub 2020 Jul 27. Drug Metab Dispos. 2020. PMID: 32719086
In metabonomics, several metabolic pathways were found to mediate the liver injury induced by acetaminophen (APAP), and SLE could regulate the disorder of lipid metabolism. ...
In metabonomics, several metabolic pathways were found to mediate the liver injury induced by acetaminophen (APAP), and SLE could reg …
Comparative Metabolomics Analysis Reveals the Unique Nutritional Characteristics of Breed and Feed on Muscles in Chinese Taihe Black-Bone Silky Fowl.
Liao X, Shi X, Hu H, Han X, Jiang K, Liu Y, Xiong G. Liao X, et al. Metabolites. 2022 Sep 27;12(10):914. doi: 10.3390/metabo12100914. Metabolites. 2022. PMID: 36295816 Free PMC article.
Secondly, we identified the metabolic alterations in Taihe silky fowl by performing an un-targeted UHPLC-Q-TOF-MS/MS analysis. Our results suggested that all the metabonomic characteristics had obvious separation between TBsf-ncf, TBsf-bpf and BF-gsc groups, both in the po …
Secondly, we identified the metabolic alterations in Taihe silky fowl by performing an un-targeted UHPLC-Q-TOF-MS/MS analysis. Our re …
Time-course expression profile and diagnostic potential of a miRNA panel in exosomes and total serum in acute liver injury.
Motawi TK, Mohamed MR, Shahin NN, Ali MAM, Azzam MA. Motawi TK, et al. Int J Biochem Cell Biol. 2018 Jul;100:11-21. doi: 10.1016/j.biocel.2018.05.002. Epub 2018 May 5. Int J Biochem Cell Biol. 2018. PMID: 29738828
Exosomes were isolated and characterized in terms of morphology, size and CD-63 surface marker expression. Exosomal, serum and hepatic miRNAs were quantified using q-RT-PCR. An inverse expression pattern of hepatic and total serum miRNAs was observed following acetamino …
Exosomes were isolated and characterized in terms of morphology, size and CD-63 surface marker expression. Exosomal, serum and hepatic miRNA …
Investigation of proteomic biomarkers in in vivo hepatotoxicity study of rat liver: toxicity differentiation in hepatotoxicants.
Yamamoto T, Kikkawa R, Yamada H, Horii I. Yamamoto T, et al. J Toxicol Sci. 2006 Feb;31(1):49-60. doi: 10.2131/jts.31.49. J Toxicol Sci. 2006. PMID: 16538043 Free article.
We investigated the overall protein expression profiles in the in vivo hepatotoxicity of rats induced by four well-recognized hepatotoxicants. Acetaminophen (APAP), amiodarone (AMD), tetracycline (TC) and carbon tetrachloride (CTC) were administered to male rats by gavages …
We investigated the overall protein expression profiles in the in vivo hepatotoxicity of rats induced by four well-recognized hepatotoxicant …