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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1969 1
1970 2
1971 1
1972 2
1975 1
1976 1
1978 3
1979 2
1980 2
1981 5
1982 5
1984 3
1985 1
1986 1
1987 3
1988 4
1989 7
1990 4
1991 3
1992 6
1993 3
1994 3
1995 2
1996 8
1997 4
1998 6
1999 9
2000 4
2001 3
2002 10
2003 4
2004 9
2005 4
2006 3
2007 6
2008 4
2009 5
2010 7
2011 2
2012 3
2013 5
2014 3
2015 6
2016 4
2017 4
2018 6
2019 6
2020 4
2021 5
2022 2
2023 1
2024 1

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187 results

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Page 1
Clinical pharmacokinetics of chlorpheniramine.
Rumore MM. Rumore MM. Drug Intell Clin Pharm. 1984 Sep;18(9):701-7. doi: 10.1177/106002808401800905. Drug Intell Clin Pharm. 1984. PMID: 6383755 Review.
The clinical pharmacokinetics of chlorpheniramine are reviewed. Recent studies have established that the half-life of chlorpheniramine is longer than previously reported. ...The use of pharmacokinetic parameters of chlorpheniramine for clinical …
The clinical pharmacokinetics of chlorpheniramine are reviewed. Recent studies have established that the half-life of chlor …
Stereoselective pharmacokinetics of chlorpheniramine and the effect of ranitidine.
Koch KM, O'Connor-Semmes RL, Davis IM, Yin Y. Koch KM, et al. J Pharm Sci. 1998 Sep;87(9):1097-100. doi: 10.1021/js980045m. J Pharm Sci. 1998. PMID: 9724561 Clinical Trial.
This single-dose, randomized, crossover study was carried out to investigate the potential effect of ranitidine on the pharmacokinetics of chlorpheniramine. The study also afforded an opportunity to add to the limited data currently available on the stereoselective …
This single-dose, randomized, crossover study was carried out to investigate the potential effect of ranitidine on the pharmacokinetics …
Pharmacokinetics and efficacy of chlorpheniramine in children.
Simons FE, Luciuk GH, Simons KJ. Simons FE, et al. J Allergy Clin Immunol. 1982 Apr;69(4):376-81. doi: 10.1016/0091-6749(82)90149-x. J Allergy Clin Immunol. 1982. PMID: 7069073
Chlorpheniramine is widely used, but there is very little information about its pharmacokinetics and efficacy in children. ...This combined with the large volume of distribution for the drug, suggest that tissue binding is an important aspect of chlorpheniramine …
Chlorpheniramine is widely used, but there is very little information about its pharmacokinetics and efficacy in children. ... …
Pharmacokinetics of intravenous chlorpheniramine in children.
Thompson JA, Bloedow DC, Leffert FH. Thompson JA, et al. J Pharm Sci. 1981 Nov;70(11):1284-6. doi: 10.1002/jps.2600701127. J Pharm Sci. 1981. PMID: 7299679
The disposition of chlorpheniramine was examined in seven children, 6-14 years of age, following a 0.1 mg/kg iv dose. ...The chlorpheniramine elimination half-life in children (mean of 9.6 hr) appeared shorter than that in adults, probably due to higher chlorphen …
The disposition of chlorpheniramine was examined in seven children, 6-14 years of age, following a 0.1 mg/kg iv dose. ...The chlor …
The roles of CYP2D6 and stereoselectivity in the clinical pharmacokinetics of chlorpheniramine.
Yasuda SU, Zannikos P, Young AE, Fried KM, Wainer IW, Woosley RL. Yasuda SU, et al. Br J Clin Pharmacol. 2002 May;53(5):519-25. doi: 10.1046/j.1365-2125.2002.01578.x. Br J Clin Pharmacol. 2002. PMID: 11994058 Free PMC article. Clinical Trial.
AIMS: To examine the stereoselective disposition of chlorpheniramine and to evaluate the role of CYP2D6 in chlorpheniramine pharmacokinetics in humans. ...CYP2D6 plays a role in the metabolism of chlorpheniramine in humans....
AIMS: To examine the stereoselective disposition of chlorpheniramine and to evaluate the role of CYP2D6 in chlorpheniramine …
Drugs for cough.
[No authors listed] [No authors listed] Med Lett Drugs Ther. 2018 Dec 17;60(1562):206-208. Med Lett Drugs Ther. 2018. PMID: 30625123 Review. No abstract available.
Pharmacokinetics and pharmacodynamics of terfenadine and chlorpheniramine in the elderly.
Simons KJ, Martin TJ, Watson WT, Simons FE. Simons KJ, et al. J Allergy Clin Immunol. 1990 Mar;85(3):540-7. doi: 10.1016/0091-6749(90)90091-h. J Allergy Clin Immunol. 1990. PMID: 2107240 Clinical Trial.
In a double-blind, randomized, crossover study, the H1-receptor antagonists, terfenadine and chlorpheniramine, were investigated in eight healthy, fasting female subjects, aged 67.8 +/- SD 0.8 years, who ingested single doses of terfenadine, 1 mg/kg (mean dose, 69.6 +/- 11 …
In a double-blind, randomized, crossover study, the H1-receptor antagonists, terfenadine and chlorpheniramine, were investigated in e …
Effect of cimetidine on the pharmacokinetics and pharmacodynamics of chlorpheniramine and diphenhydramine in rabbits.
Simons KJ, Chen X, Fraser TG, Simons FE. Simons KJ, et al. Pharm Res. 1996 Feb;13(2):301-4. doi: 10.1023/a:1016011702703. Pharm Res. 1996. PMID: 8932453
PURPOSE: The effects of concomitant administration of the H2-receptor antagonist cimetidine on the pharmacokinetics and pharmacodynamics of the H1-receptor antagonists chlorpheniramine and diphenhydramine were studied in rabbits. ...Serum chlorpheniramine and …
PURPOSE: The effects of concomitant administration of the H2-receptor antagonist cimetidine on the pharmacokinetics and pharmacodynam …
Brompheniramine and Chlorpheniramine Pharmacokinetics Following Single-Dose Oral Administration in Children Aged 2 to 17 Years.
Pathirana S, Jayawardena S, Meeves S, Thompson GA. Pathirana S, et al. J Clin Pharmacol. 2018 Apr;58(4):494-503. doi: 10.1002/jcph.1037. Epub 2017 Nov 14. J Clin Pharmacol. 2018. PMID: 29136286 Clinical Trial.
Two pediatric studies characterized brompheniramine and chlorpheniramine pharmacokinetics in a total of 72 subjects, aged 2 to 17 years. ...Results indicated that for brompheniramine and chlorpheniramine, C(max) was similar across age groups, although it tend …
Two pediatric studies characterized brompheniramine and chlorpheniramine pharmacokinetics in a total of 72 subjects, aged 2 to …
Pharmacokinetics of chlorpheniramine after intravenous and oral administration in normal adults.
Huang SM, Athanikar NK, Sridhar K, Huang YC, Chiou WL. Huang SM, et al. Eur J Clin Pharmacol. 1982;22(4):359-65. doi: 10.1007/BF00548406. Eur J Clin Pharmacol. 1982. PMID: 7106172
Plasma and urinary levels of chlorpheniramine (CPM) and its 2 demethylated metabolites were measured by HPLC after i.v. and oral dosing. ...
Plasma and urinary levels of chlorpheniramine (CPM) and its 2 demethylated metabolites were measured by HPLC after i.v. and oral dosi …
187 results