Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 2
1976 2
1977 2
1978 1
1979 1
1980 5
1981 1
1982 2
1983 3
1984 3
1985 3
1986 2
1987 2
1988 3
1989 6
1990 7
1991 4
1992 12
1993 8
1994 7
1995 14
1996 22
1997 19
1998 29
1999 44
2000 49
2001 78
2002 74
2003 88
2004 108
2005 104
2006 143
2007 167
2008 215
2009 203
2010 217
2011 252
2012 287
2013 289
2014 302
2015 318
2016 351
2017 362
2018 402
2019 423
2020 460
2021 474
2022 447
2023 467
2024 444
2025 535
2026 320

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

533 results

Results by year

Filters applied: in the last 1 year. Clear all
Page 1
Metformin attenuates colitis via blocking STAT3 acetylation by reducing acetyl-CoA production.
Li X, Xiang Z, Wang X, He H, Xu M, Tan C, Wu X, Zhang J, Dong W. Li X, et al. J Adv Res. 2026 Jan;79:393-407. doi: 10.1016/j.jare.2025.03.058. Epub 2025 Mar 31. J Adv Res. 2026. PMID: 40174640 Free PMC article.
This study investigates the role of acetyl coenzyme A (acetyl-CoA)-dependent STAT3 acetylation in mediating metformin's therapeutic actions, with the goal of identifying novel molecular targets for ulcerative colitis (UC) treatment. METHODS: Acute colitis was induced in wild …
This study investigates the role of acetyl coenzyme A (acetyl-CoA)-dependent STAT3 acetylation in mediating metformin's therapeutic actions, …
Lifelong exposure to polystyrene-nanoplastics induces an attention-deficit hyperactivity disorder-like phenotype and impairs brain aging in mice.
Vignon AN, Dudon G, Oliva G, Thirard S, Alenda UG, Brugoux A, Cazevieille C, Imbert J, Bellières C, Lehmann S, Crozet C, Torrent J, Bertaso F, Le Merrer J, Becker JAJ, Perrier V. Vignon AN, et al. J Hazard Mater. 2025 Aug 15;494:138640. doi: 10.1016/j.jhazmat.2025.138640. Epub 2025 May 16. J Hazard Mater. 2025. PMID: 40403375
The accumulation of plastic waste in the environment, breaking down into micro- and nanoplastics, poses significant threats to ecosystem and human health. Plastic particles have been detected in human blood, urine, and placental tissue, indicating widespread exposur …
The accumulation of plastic waste in the environment, breaking down into micro- and nanoplastics, poses significant threats to ecosys …
Epigenetic Regulation of DAPK1 and Netrin-1 Drives Diabetic Encephalopathy.
Zhou Y, Kou JX, Zheng K, Guo ZX, Fan HW, Li WL, Chu LL, Yin JW, Liu LJ, Brazhe N, Xiang ZG, Hu F, Shu K, Zhu LQ, Liu D. Zhou Y, et al. Adv Sci (Weinh). 2025 Oct;12(37):e02535. doi: 10.1002/advs.202502535. Epub 2025 Aug 11. Adv Sci (Weinh). 2025. PMID: 40787892 Free PMC article.
Elevated DAPK1 expression in hippocampal excitatory neurons correlates with cognitive deficits, increases neuronal apoptosis, and disrupts synaptic plasticity. Conditional knockout of DAPK1 in CaMKII-positive neurons significantly mitigates these pathological features, imp …
Elevated DAPK1 expression in hippocampal excitatory neurons correlates with cognitive deficits, increases neuronal apoptosis, and disrupts s …
The adaptor protein SKT interacts with PSD-95 and SHANK3 and affects synaptic functions.
Morellato A, De Gregorio M, Angelini C, Torelli F, Belmonte V, Alfieri A, Bersia B, Cravero T, Gai M, Bianciotto OT, Oddone R, Salemme V, Natalini D, Centonze G, Nigrelli F, Raspanti A, Gurgone A, D'Attanasio G, Mele P, Eva C, Lodi A, Gavello D, Carabelli V, Hidisoglu E, Chiantia G, Carbone E, Becchetti A, Giustetto M, Marcantoni A, Turco E, Bertocchi I, Defilippi P. Morellato A, et al. Cell Rep. 2025 Sep 23;44(9):116206. doi: 10.1016/j.celrep.2025.116206. Epub 2025 Sep 1. Cell Rep. 2025. PMID: 40892546 Free article.
Behavioral tests on KO mice reveal increased self-grooming activity and impaired motor coordination, with altered cognitive and executive functions compared to wild-type mice. Overall, SKT emerges as a key contributor to the structural and functional PSD organization, regu …
Behavioral tests on KO mice reveal increased self-grooming activity and impaired motor coordination, with altered cognitive and executive fu …
Long-term exercise enhances meningeal lymphatic vessel plasticity and drainage in a mouse model of Alzheimer's disease.
Chen Y, Cai J, She Y, He X, Feng H, Li X, Wei Y, Fan Y, Zhao WE, Yin M, Yuan L, Jin Y, Ding F, Sheng C, Gao J, Li Q, Xiao M. Chen Y, et al. Transl Neurodegener. 2025 Jul 25;14(1):37. doi: 10.1186/s40035-025-00497-2. Transl Neurodegener. 2025. PMID: 40713754 Free PMC article.
RNA sequencing, protein interactions analysis, gene knockdown mediated by adeno-associated virus, and lymphatic endothelial cell culture were conducted to investigate the mechanism underlying exercise-induced meningeal lymphatic vessel plasticity in 5 FAD mice. RESULTS: …
RNA sequencing, protein interactions analysis, gene knockdown mediated by adeno-associated virus, and lymphatic endothelial cell culture wer …
Osteopontin attenuates the foreign-body response to silicone implants.
Griffin MF, Parker JB, Tevlin R, Liang NE, Valencia C, Morgan A, Kuhnert M, Downer M Jr, Meany EL, Guo JL, Henn D, Navarro RS, Shefren K, Nguyen D, Gurtner GC, Heilshorn SC, Chan CKF, Januszyk M, Appel EA, Momeni A, Wan DC, Longaker MT. Griffin MF, et al. Nat Biomed Eng. 2025 Aug;9(8):1254-1275. doi: 10.1038/s41551-025-01361-4. Epub 2025 Mar 24. Nat Biomed Eng. 2025. PMID: 40128393 Free PMC article.
In mice with osteopontin knocked out, FBR attenuation by ADM-coated implants was abrogated. In wild-type mice, the sustained release of recombinant osteopontin from a hydrogel placed adjacent to a silicone implant attenuated the FBR in the absence of ADM. ...
In mice with osteopontin knocked out, FBR attenuation by ADM-coated implants was abrogated. In wild-type mice, the sustained release …
Global burden of enteric infectious diseases, diarrhoeal diseases, and corresponding aetiologies, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.
GBD 2023 Diarrhoeal Disease and Enteric Infectious Diseases Collaborators. GBD 2023 Diarrhoeal Disease and Enteric Infectious Diseases Collaborators. Lancet Infect Dis. 2026 Jun 2:S1473-3099(26)00194-5. doi: 10.1016/S1473-3099(26)00194-5. Online ahead of print. Lancet Infect Dis. 2026. PMID: 42229499
Cognitive loss after brain trauma results from sex-specific activation of synaptic pruning processes.
Arizanovska D, Bush GF, Dallera CA, Folorunso OO, Frye JB, Doyle KP, Jagid JR, Wolosker H, Monaco BA, Graciolli Cordeiro J, Atkins CM, Griswold AJ, Liebl DJ. Arizanovska D, et al. Brain. 2026 Mar 5;149(3):918-933. doi: 10.1093/brain/awaf293. Brain. 2026. PMID: 40796363 Free PMC article.
To examine whether expansive global synaptic damage underlies cognitive losses associated with brain injury, we evaluated the influence of D-serine on synaptic damage in male and female wild-type mice as well as mice deficient in microglial serine racemase (TMEM119creErt2: …
To examine whether expansive global synaptic damage underlies cognitive losses associated with brain injury, we evaluated the influence of D …
Suppression of miR-148a-3p Can Promote Bone Healing by Enhancing Angiogenesis-Osteogenesis Coupling Through the PI3K/Akt Pathway.
Li X, Rong K, Huang Y, Zhao Z, Xu C, Lin L, Zhang Y, Yan Y, Huang W, Zhang Y, Li L, Hou M, Chai G, Zhang Y, Chen X. Li X, et al. FASEB J. 2025 Aug 31;39(16):e70930. doi: 10.1096/fj.202500432R. FASEB J. 2025. PMID: 40793981
This study aimed to elucidate the role and mechanism of miR-148a-3p in bone physiology using miR-148a knockout (KO) mice. Compared to wild-type and heterozygous littermates, miR-148a KO mice demonstrated smaller body size but exhibited increased bone mass, enhanced type H …
This study aimed to elucidate the role and mechanism of miR-148a-3p in bone physiology using miR-148a knockout (KO) mice. Compared to wil …
Nusinersen corrects L-arginine deficiency in the cerebrospinal fluid of patients with severe spinal muscular atrophy.
Hassan A, di Vito R, Caretto A, Nuzzo T, D'Amico A, Panicucci C, Bruno C, Bertini E, Vercelli A, Boido M, Errico F, Pellizzoni L, Usiello A. Hassan A, et al. Neurobiol Dis. 2025 Oct 1;214:107046. doi: 10.1016/j.nbd.2025.107046. Epub 2025 Jul 31. Neurobiol Dis. 2025. PMID: 40752627 Free PMC article.
L-arginine, a precursor of nitric oxide, plays a critical role in glutamatergic receptor signalling, influencing neurotransmitter release, synaptic plasticity, and neuroprotection. However, it remains unclear whether SMN deficiency affects L-arginine metabolism in SMA. ... …
L-arginine, a precursor of nitric oxide, plays a critical role in glutamatergic receptor signalling, influencing neurotransmitter release, s …
533 results