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Page 1
Showing results for pregabalin
Search for pregalin instead (1 results)
Benefits and harms of pregabalin in the management of neuropathic pain: a rapid review and meta-analysis of randomised clinical trials.
Onakpoya IJ, Thomas ET, Lee JJ, Goldacre B, Heneghan CJ. Onakpoya IJ, et al. BMJ Open. 2019 Jan 21;9(1):e023600. doi: 10.1136/bmjopen-2018-023600. BMJ Open. 2019. PMID: 30670513 Free PMC article. Review.
Pregabalin significantly increased the risk of adverse events compared with placebo (RR 1.33 (95% CI 1.23 to 1.44, p<0.00001, low quality evidence)). ...CONCLUSION: Pregabalin has beneficial effects on some symptoms of neuropathic pain. ...
Pregabalin significantly increased the risk of adverse events compared with placebo (RR 1.33 (95% CI 1.23 to 1.44, p<0.00001, low …
Pregabalin for neuropathic pain in adults.
Derry S, Bell RF, Straube S, Wiffen PJ, Aldington D, Moore RA. Derry S, et al. Cochrane Database Syst Rev. 2019 Jan 23;1(1):CD007076. doi: 10.1002/14651858.CD007076.pub3. Cochrane Database Syst Rev. 2019. PMID: 30673120 Free PMC article.
Antiepileptic drugs have long been used in pain management. Pregabalin is an antiepileptic drug used in management of chronic pain conditions. ...Somnolence (32% vs 11%) and dizziness (23% vs 8.6%) were more common with pregabalin.Other neuropathic pain conditions: …
Antiepileptic drugs have long been used in pain management. Pregabalin is an antiepileptic drug used in management of chronic pain co …
Is there a role for combined use of gabapentin and pregabalin in pain control? Too good to be true?
Senderovich H, Jeyapragasan G. Senderovich H, et al. Curr Med Res Opin. 2018 Apr;34(4):677-682. doi: 10.1080/03007995.2017.1391756. Epub 2017 Dec 4. Curr Med Res Opin. 2018. PMID: 29023146 Review.
Gabapentin (Neurontin (1) ) and pregabalin (Lyrica (2) ) are first- and second-generation alpha2delta ligands, respectively, and are both approved for use as adjunctive therapy in pain control. ...Pharmacokinetics, drug interactions, and adverse reaction to combinations ha …
Gabapentin (Neurontin (1) ) and pregabalin (Lyrica (2) ) are first- and second-generation alpha2delta ligands, respectively, and are …
Pregabalin add-on for drug-resistant focal epilepsy.
Panebianco M, Bresnahan R, Marson AG. Panebianco M, et al. Cochrane Database Syst Rev. 2022 Mar 29;3(3):CD005612. doi: 10.1002/14651858.CD005612.pub5. Cochrane Database Syst Rev. 2022. PMID: 35349176 Free PMC article. Review.
However, significantly fewer participants achieved seizure freedom with add-on pregabalin compared to eventrate (RR 0.50, 95% CI 0.30 to 0.85). No data were reported for this outcome for pregabalin versus gabapentin. ...Likewise, no inference can be made about the e …
However, significantly fewer participants achieved seizure freedom with add-on pregabalin compared to eventrate (RR 0.50, 95% CI 0.30 …
Abuse and Misuse of Pregabalin and Gabapentin: A Systematic Review Update.
Evoy KE, Sadrameli S, Contreras J, Covvey JR, Peckham AM, Morrison MD. Evoy KE, et al. Drugs. 2021 Jan;81(1):125-156. doi: 10.1007/s40265-020-01432-7. Drugs. 2021. PMID: 33215352
BACKGROUND: A 2017 systematic review (SR) identified 59 studies examining gabapentinoid (pregabalin and gabapentin) misuse/abuse. Evidence of gabapentinoid misuse/abuse has since grown substantially. ...Reference lists of included studies were reviewed to identify addition …
BACKGROUND: A 2017 systematic review (SR) identified 59 studies examining gabapentinoid (pregabalin and gabapentin) misuse/abuse. Evi …
Pregabalin mitigates microglial activation and neuronal injury by inhibiting HMGB1 signaling pathway in radiation-induced brain injury.
Zhang Z, Jiang J, He Y, Cai J, Xie J, Wu M, Xing M, Zhang Z, Chang H, Yu P, Chen S, Yang Y, Shi Z, Liu Q, Sun H, He B, Zeng J, Huang J, Chen J, Li H, Li Y, Lin WJ, Tang Y. Zhang Z, et al. J Neuroinflammation. 2022 Sep 21;19(1):231. doi: 10.1186/s12974-022-02596-7. J Neuroinflammation. 2022. PMID: 36131309 Free PMC article.
RESULTS: Our findings showed that pregabalin effectively repressed microglial activation, thereby reducing neuronal damage in the RIBI mouse model. ...CONCLUSIONS: Our findings indicate the protective mechanism of pregabalin in mitigating microglial activation and n …
RESULTS: Our findings showed that pregabalin effectively repressed microglial activation, thereby reducing neuronal damage in the RIB …
Alpha(2)delta ligands, gabapentin, pregabalin and mirogabalin: a review of their clinical pharmacology and therapeutic use.
Calandre EP, Rico-Villademoros F, Slim M. Calandre EP, et al. Expert Rev Neurother. 2016 Nov;16(11):1263-1277. doi: 10.1080/14737175.2016.1202764. Epub 2016 Jul 7. Expert Rev Neurother. 2016. PMID: 27345098 Review.
The first two alpha(2)delta ligands - gabapentin (GBP) and pregabalin (PGB) - were initially synthesized as antiepileptics; however, they were later also found to be useful for the treatment of additional conditions. ...
The first two alpha(2)delta ligands - gabapentin (GBP) and pregabalin (PGB) - were initially synthesized as antiepileptics; however, …
Pregabalin Induced Maculopapular Eruption in an Elderly Male.
Jaiswal S, Chakrabarti SS, Rai T, Dhameja N, Mohan A, Yadav V, Kaur U. Jaiswal S, et al. Curr Drug Saf. 2022;17(4):393-398. doi: 10.2174/1574886317666220309143913. Curr Drug Saf. 2022. PMID: 35264095 Review.
BACKGROUND: Pregabalin is used in the treatment of neuropathic pain of various etiologies and as an adjuvant in epilepsy. ...CONCLUSION: We have also conducted a literature review of similar cases and highlighted the clinical patterns and management strategies for prega …
BACKGROUND: Pregabalin is used in the treatment of neuropathic pain of various etiologies and as an adjuvant in epilepsy. ...CONCLUSI …
Safety of Pregabalin in Pregnancy.
Andrade C. Andrade C. J Clin Psychiatry. 2018 Oct 2;79(5):18f12568. doi: 10.4088/JCP.18f12568. J Clin Psychiatry. 2018. PMID: 30289631 Free article. Review.
In different parts of the world, pregabalin is an approved treatment for neuropathic pain syndromes, fibromyalgia, partial-onset seizures, and generalized anxiety disorder. ...Pregabalin use in pregnancy is therefore best restricted to circumstances in which the ris …
In different parts of the world, pregabalin is an approved treatment for neuropathic pain syndromes, fibromyalgia, partial-onset seiz …
4,928 results