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1925 1
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Page 1
Purpurin suppresses atopic dermatitis via TNF-alpha/IFN-gamma-induced inflammation in HaCaT cells.
Oh JH, Kim SH, Kwon OK, Kim JH, Oh SR, Han SB, Park JW, Ahn KS. Oh JH, et al. Int J Immunopathol Pharmacol. 2022 Jan-Dec;36:3946320221111135. doi: 10.1177/03946320221111135. Int J Immunopathol Pharmacol. 2022. PMID: 35794850 Free PMC article.
OBJECTIVE: We investigated whether purpurin inhibits various pathways of inflammation leading to atopic dermatitis. INTRODUCTION: 1,2,4-Trihydroxyanthraquinone, commonly called purpurin, is an anthraquinone that is a naturally occurring red/yellow dye. ...
OBJECTIVE: We investigated whether purpurin inhibits various pathways of inflammation leading to atopic dermatitis. INTRODUCTION: 1,2 …
Microenvironment-Responsive Prodrug-Induced Pyroptosis Boosts Cancer Immunotherapy.
Xiao Y, Zhang T, Ma X, Yang QC, Yang LL, Yang SC, Liang M, Xu Z, Sun ZJ. Xiao Y, et al. Adv Sci (Weinh). 2021 Dec;8(24):e2101840. doi: 10.1002/advs.202101840. Epub 2021 Oct 27. Adv Sci (Weinh). 2021. PMID: 34705343 Free PMC article.
Here, a smart tumor microenvironmental reactive oxygen species (ROS)/glutathione (GSH) dual-responsive nano-prodrug (denoted as MCPP) with high paclitaxel (PTX) and photosensitizer purpurin 18 (P18) loading is rationally designed. The ROS/GSH dual-responsive system facilit …
Here, a smart tumor microenvironmental reactive oxygen species (ROS)/glutathione (GSH) dual-responsive nano-prodrug (denoted as MCPP) with h …
Microbial glucosidation of 1,2,4-trihydroxy-9,10-anthraquinone (purpurin).
Steinerová N, Matĕjů J, Cudlín J, Vanĕk Z. Steinerová N, et al. Folia Microbiol (Praha). 1984;29(6):433-40. doi: 10.1007/BF02873156. Folia Microbiol (Praha). 1984. PMID: 6441760
Streptomyces aureofaciens glucosidizes 1,2,4-trihydroxy-9,10-anthraquinone (purpurin) added to the cultivation medium to yield the corresponding 2-beta-D-glucoside. ...A further chemical glucosidation of the acetylated 2-beta-D-glucoside gives rise to 2-(hepta-O-acetyl-bet …
Streptomyces aureofaciens glucosidizes 1,2,4-trihydroxy-9,10-anthraquinone (purpurin) added to the cultivation medium to yield the co …
Purpurin ameliorates D-galactose-induced aging phenotypes in mouse hippocampus by reducing inflammatory responses.
Kwon HJ, Hahn KR, Nam SM, Yoon YS, Moon SM, Hwang IK, Kim DW. Kwon HJ, et al. Neurochem Int. 2023 Jul;167:105552. doi: 10.1016/j.neuint.2023.105552. Epub 2023 May 23. Neurochem Int. 2023. PMID: 37230197
Purpurin, an anthraquinone, has potent anti-oxidant and anti-inflammatory effects in various types of brain damage. In a previous study, we showed that purpurin exerts neuroprotective effects against oxidative and ischemic damage by reducing pro-inflammatory cytokin …
Purpurin, an anthraquinone, has potent anti-oxidant and anti-inflammatory effects in various types of brain damage. In a previous stu …
Purpurin: A natural anthraquinone with multifaceted pharmacological activities.
Singh J, Hussain Y, Luqman S, Meena A. Singh J, et al. Phytother Res. 2021 May;35(5):2418-2428. doi: 10.1002/ptr.6965. Epub 2020 Nov 30. Phytother Res. 2021. PMID: 33254282 Review.
Purpurin is a naturally occurring anthraquinone isolated from the roots of Rubia cordifolia. ...It also covers physicochemical, pharmacokinetics, and toxicology aspects of purpurin. Moreover, in the end, the prospect of purpurin in the management of cancer ha …
Purpurin is a naturally occurring anthraquinone isolated from the roots of Rubia cordifolia. ...It also covers physicochemical, pharm …
Copper-mediated DNA damage caused by purpurin, a natural anthraquinone.
Kobayashi H, Mori Y, Iwasa R, Hirao Y, Kato S, Kawanishi S, Murata M, Oikawa S. Kobayashi H, et al. Genes Environ. 2022 May 9;44(1):15. doi: 10.1186/s41021-022-00245-2. Genes Environ. 2022. PMID: 35527257 Free PMC article.
Many carcinogenic dyes are known to induce bladder cancers via DNA adduct formation, but carcinogenic mechanisms of purpurin remain unknown. In this study, to clarify the mechanism underlying carcinogenicity of purpurin, copper-mediated DNA damage induced by purp …
Many carcinogenic dyes are known to induce bladder cancers via DNA adduct formation, but carcinogenic mechanisms of purpurin remain u …
The Effective Treatment of Purpurin on Inflammation and Adjuvant-Induced Arthritis.
Zeng W, Shen C, Mo S, Ni C, Lin Y, Fang Y, Yang H, Luo G, Xiao L, Zhan R, Yan P. Zeng W, et al. Molecules. 2023 Jan 2;28(1):366. doi: 10.3390/molecules28010366. Molecules. 2023. PMID: 36615560 Free PMC article.
Furthermore, purpurin reduced the MMP3 content of AIA rats. Network pharmacology and molecular docking also suggested that MMP3 may be the key target of purpurin against RA. The results of this study strongly indicated that purpurin has a potential effect on …
Furthermore, purpurin reduced the MMP3 content of AIA rats. Network pharmacology and molecular docking also suggested that MMP3 may b …
Synthesis and crystal structures of two purpurin derivatives: 1,4-dihy-droxy-2-propoxyanthra-quinone and 2-but-oxy-1,4-di-hydroxy-anthra-quinone.
Bosch E, McClain EN. Bosch E, et al. Acta Crystallogr E Crystallogr Commun. 2017 Oct 20;73(Pt 11):1687-1691. doi: 10.1107/S2056989017014724. eCollection 2017 Nov 1. Acta Crystallogr E Crystallogr Commun. 2017. PMID: 29152351 Free PMC article.
The title compounds were obtained by deprotonation of 1,2,4-tri-hydroxy-anthra-quinone (purpurin) using sodium hydride followed by reaction with either 1-bromo-propane or 1-bromo-butane. 1,4-Dihy-droxy-2-propoxyanthra-quinone crystallizes as a 1:1 solvate from aceto-nitril …
The title compounds were obtained by deprotonation of 1,2,4-tri-hydroxy-anthra-quinone (purpurin) using sodium hydride followed by re …
Dose-dependent binding behavior of anthraquinone derivative purpurin interacting with tau-derived peptide protofibril.
Wu X, Zhu L, Wang G, Zhang Q, Qian Z. Wu X, et al. Phys Chem Chem Phys. 2023 Oct 11;25(39):26787-26796. doi: 10.1039/d3cp03883a. Phys Chem Chem Phys. 2023. PMID: 37781899
With increasing purpurin/peptide ratio, purpurins tend to self-aggregate rather than bind to the protein surface. ...Aromatic stacking plays a key role in the octamer-purpurin interaction, in which the three aromatic rings of purpurin have different co …
With increasing purpurin/peptide ratio, purpurins tend to self-aggregate rather than bind to the protein surface. ...Aromatic …
301 results