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Rasburicase.
[No authors listed] [No authors listed] 2023 Nov 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2023 Nov 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 29999664 Free Books & Documents. Review.
No information is available on the clinical use of rasburicase during breastfeeding. Because it is a large protein molecule with a molecular weight of about 34,000 Da, the amount in milk is likely to be very low and absorption is unlikely because it is probably partly dest …
No information is available on the clinical use of rasburicase during breastfeeding. Because it is a large protein molecule with a mo …
Rasburicase.
[No authors listed] [No authors listed] 2018 May 21. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2018 May 21. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643804 Free Books & Documents. Review.
Rasburicase is a parenterally administered, recombinant urate oxidase that is used in combination with xanthine oxidase inhibitors in the therapy of severe hyperuricemia due to tumor lysis syndrome after initiation of cancer chemotherapy in treatment of malignant diseases.
Rasburicase is a parenterally administered, recombinant urate oxidase that is used in combination with xanthine oxidase inhibitors in
Rasburicase Therapy and G6PD and CYB5R Genotype.
Dean L, Kane M. Dean L, et al. 2020 Sep 29. In: Pratt VM, Scott SA, Pirmohamed M, Esquivel B, Kattman BL, Malheiro AJ, editors. Medical Genetics Summaries [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2012–. 2020 Sep 29. In: Pratt VM, Scott SA, Pirmohamed M, Esquivel B, Kattman BL, Malheiro AJ, editors. Medical Genetics Summaries [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2012–. PMID: 32997466 Free Books & Documents. Review.
However, they are at risk of life-threating hemolytic reactions and methemoglobinemia if given oxidizing drugs such as rasburicase. Rasburicase is contraindicated in individuals with G6PD deficiency. ...The CPIC states for individuals with normal G6PD phenotype, the …
However, they are at risk of life-threating hemolytic reactions and methemoglobinemia if given oxidizing drugs such as rasburicase. …
Rasburicase-induced hemolytic anemia and methemoglobinemia: a systematic review of current reports.
Hammami MB, Qasim A, Thakur R, Vegivinti CTR, Patton CD, Vikash S, Kumar A. Hammami MB, et al. Ann Hematol. 2023 Jul 19. doi: 10.1007/s00277-023-05364-6. Online ahead of print. Ann Hematol. 2023. PMID: 37468669 Review.
Since the FDA's approval of rasburicase use for treatment of tumor lysis syndrome (TLS), multiple cases of rasburicase-induced methemoglobinemia and hemolytic anemia have been reported among patients with G6PD deficiency. ...Forty-three cases, including a case from …
Since the FDA's approval of rasburicase use for treatment of tumor lysis syndrome (TLS), multiple cases of rasburicase-induced …
Rasburicase-Induced Methemoglobinemia.
Ahmed M, Sanchez T, Norgbe S, Picking CR, Millner PG. Ahmed M, et al. Cureus. 2021 Apr 10;13(4):e14406. doi: 10.7759/cureus.14406. Cureus. 2021. PMID: 33987056 Free PMC article.
Methemoglobinemia occurs as iron in heme is oxidized to its ferric state, resulting in a decreased ability of hemoglobin to bind and release oxygen. Rasburicase is a recombinant urate-oxidase enzyme used in the prevention of tumor lysis syndrome. Methemoglobinemia can occu …
Methemoglobinemia occurs as iron in heme is oxidized to its ferric state, resulting in a decreased ability of hemoglobin to bind and release …
Rasburicase in treating tumor lysis syndrome: An umbrella review.
Mahfooz K, Sohail H, Gvajaia A, Arif U, Grewal D, Muppidi MR, Vohra V, Tarique A, Vasavada A. Mahfooz K, et al. Cancer Pathog Ther. 2023 Jul 20;1(4):262-271. doi: 10.1016/j.cpt.2023.07.001. eCollection 2023 Oct. Cancer Pathog Ther. 2023. PMID: 38327601 Free PMC article. Review.
Most outcomes did not differ significantly compared with those of allopurinol. Future trials should focus on the cost-effectiveness of rasburicase compared to that of allopurinol while including high-, intermediate-, and low-risk patients. Rasburicase is safe and ef …
Most outcomes did not differ significantly compared with those of allopurinol. Future trials should focus on the cost-effectiveness of ra
Rasburicase-induced Methemoglobinemia: A Case Report and Literature Review.
Pirrone I, Farruggia P, Cacciatore F, Giambona A, Guarina A, Marcello AP, Mosa C, Scalzo S, D'Angelo P. Pirrone I, et al. J Pediatr Hematol Oncol. 2021 Aug 1;43(6):e886-e890. doi: 10.1097/MPH.0000000000001979. J Pediatr Hematol Oncol. 2021. PMID: 33122582 Review.
Rasburicase is a recombinant urate oxidase enzyme indicated for tumor lysis syndrome, a potential life-threatening oncologic emergency that occurs most commonly during initial chemotherapy for hematological malignancies. As a result of the defects in the physiological anti
Rasburicase is a recombinant urate oxidase enzyme indicated for tumor lysis syndrome, a potential life-threatening oncologic emergenc
Rescue Therapies for AKI in Onconephrology: Rasburicase and Glucarpidase.
Latcha S, Shah CV. Latcha S, et al. Semin Nephrol. 2022 Nov;42(6):151342. doi: 10.1016/j.semnephrol.2023.151342. Epub 2023 May 9. Semin Nephrol. 2022. PMID: 37167817 Review.
Tumor lysis syndrome (TLS) and high-dose methotrexate (HD MTX) toxicity can present with potentially severe complications, including acute kidney injury, in patients with malignancy. Guidelines for using rasburicase and glucarpidase as rescue therapies for TLS and HD MTX t …
Tumor lysis syndrome (TLS) and high-dose methotrexate (HD MTX) toxicity can present with potentially severe complications, including acute k …
Rasburicase-Induced Methemoglobinemia in a Patient with Glucose-6- Phosphate Dehydrogenase Deficiency.
Khan M, Paul S, Farooq S, Oo TH, Ramshesh P, Jain N. Khan M, et al. Curr Drug Saf. 2017;12(1):13-18. doi: 10.2174/1574886312666170111151246. Curr Drug Saf. 2017. PMID: 28078984 Review.
BACKGROUND: Rasburicase is commonly used in patients with hematologic malignancies for tumor lysis syndrome prophylaxis and management. ...RESULTS: Rasburicase-induced methemoglobinemia is more common in patients with G6PD deficiency, and rasburicase is there …
BACKGROUND: Rasburicase is commonly used in patients with hematologic malignancies for tumor lysis syndrome prophylaxis and managemen …
Tumor Lysis Syndrome.
Barbar T, Jaffer Sathick I. Barbar T, et al. Adv Chronic Kidney Dis. 2021 Sep;28(5):438-446.e1. doi: 10.1053/j.ackd.2021.09.007. Adv Chronic Kidney Dis. 2021. PMID: 35190110 Review.
Management includes intravenous hydration to maintain urine flow, medications targeting hyperuricemia including rasburicase and allopurinol and in severe cases renal replacement therapy may be required....
Management includes intravenous hydration to maintain urine flow, medications targeting hyperuricemia including rasburicase and allop …
531 results