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11,269 results

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Page 1
Showing results for receptor zinc
Your search for receptozine retrieved no results
The Zinc-Sensing Receptor GPR39 in Physiology and as a Pharmacological Target.
Laitakari A, Liu L, Frimurer TM, Holst B. Laitakari A, et al. Int J Mol Sci. 2021 Apr 8;22(8):3872. doi: 10.3390/ijms22083872. Int J Mol Sci. 2021. PMID: 33918078 Free PMC article. Review.
The G-protein coupled receptor GPR39 is abundantly expressed in various tissues and can be activated by changes in extracellular Zn(2+) in physiological concentrations. ...
The G-protein coupled receptor GPR39 is abundantly expressed in various tissues and can be activated by changes in extracellular Zn(2 …
Interaction between zinc, the GPR39 zinc receptor and the serotonergic system in depression.
Siodłak D, Nowak G, Mlyniec K. Siodłak D, et al. Brain Res Bull. 2021 May;170:146-154. doi: 10.1016/j.brainresbull.2021.02.003. Epub 2021 Feb 4. Brain Res Bull. 2021. PMID: 33549699 Review.
Studying this disease and designing effective treatment is hampered by its heterogeneous etiology and the diversified nature of the symptoms. Over the years, studies have shown that zinc deficiency and disturbances in the expression profile of the zinc receptor
Studying this disease and designing effective treatment is hampered by its heterogeneous etiology and the diversified nature of the symptoms …
The Zinc Sensing Receptor, ZnR/GPR39, in Health and Disease.
Hershfinkel M. Hershfinkel M. Int J Mol Sci. 2018 Feb 1;19(2):439. doi: 10.3390/ijms19020439. Int J Mol Sci. 2018. PMID: 29389900 Free PMC article. Review.
A distinct G-protein coupled receptor that senses changes in extracellular Zn(2+), ZnR/GPR39, was found in cells from tissues in which Zn(2+) plays a physiological role. ...Thus, ZnR/GPR39 provides a unique target for therapeutically modifying the actions of zinc in …
A distinct G-protein coupled receptor that senses changes in extracellular Zn(2+), ZnR/GPR39, was found in cells from tissues in whic …
Functions of the Zinc-Sensing Receptor GPR39 in Regulating Intestinal Health in Animals.
Xia P, Yan L, Ji X, Wu Y, Lian S, Zhu G. Xia P, et al. Int J Mol Sci. 2022 Oct 12;23(20):12133. doi: 10.3390/ijms232012133. Int J Mol Sci. 2022. PMID: 36292986 Free PMC article. Review.
G protein-coupled receptor 39 (GPR39) is a zinc-sensing receptor (ZnR) that can sense changes in extracellular Zn(2+), mediate Zn(2+) signal transmission, and participate in the regulation of numerous physiological activities in living organisms. ...
G protein-coupled receptor 39 (GPR39) is a zinc-sensing receptor (ZnR) that can sense changes in extracellular Zn(2+), …
ZIP9, a novel membrane androgen receptor and zinc transporter protein.
Thomas P, Converse A, Berg HA. Thomas P, et al. Gen Comp Endocrinol. 2018 Feb 1;257:130-136. doi: 10.1016/j.ygcen.2017.04.016. Epub 2017 May 4. Gen Comp Endocrinol. 2018. PMID: 28479083 Review.
In 2014, a novel mAR unrelated to nuclear androgen receptors was identified in Atlantic croaker ovaries as the zinc transporter protein, ZIP9. ZIP9 is one of the 14 members of the ZIP (ZRT-and Irt-like Protein, SLC39A) family that regulates zinc homeostasis b …
In 2014, a novel mAR unrelated to nuclear androgen receptors was identified in Atlantic croaker ovaries as the zinc transporte …
MCOLN1/TRPML1 finely controls oncogenic autophagy in cancer by mediating zinc influx.
Qi J, Xing Y, Liu Y, Wang MM, Wei X, Sui Z, Ding L, Zhang Y, Lu C, Fei YH, Liu N, Chen R, Wu M, Wang L, Zhong Z, Wang T, Liu Y, Wang Y, Liu J, Xu H, Guo F, Wang W. Qi J, et al. Autophagy. 2021 Dec;17(12):4401-4422. doi: 10.1080/15548627.2021.1917132. Epub 2021 Apr 23. Autophagy. 2021. PMID: 33890549 Free PMC article.
Second, we demonstrated that MCOLN1 regulates autophagy by mediating the release of zinc from the lysosome to the cytosol. Third, we uncovered that zinc influx through MCOLN1 blocks the interaction between STX17 (syntaxin 17) in the autophagosome and VAMP8 in the ly …
Second, we demonstrated that MCOLN1 regulates autophagy by mediating the release of zinc from the lysosome to the cytosol. Third, we …
Ketamine and Zinc: Treatment of Anorexia Nervosa Via Dual NMDA Receptor Modulation.
Mitchell JS, Hermens DF, Bennett MR, Can AT, Lagopoulos J. Mitchell JS, et al. CNS Drugs. 2023 Feb;37(2):159-180. doi: 10.1007/s40263-022-00984-4. Epub 2023 Jan 22. CNS Drugs. 2023. PMID: 36681939 Free PMC article. Review.
This narrative review critically explores the role of N-methyl-D-aspartate receptor-mediated excitatory and inhibitory neurometabolite dysfunction in anorexia nervosa and its associated biomarkers. ...Considering the proposed role of dysfunctional neurotransmission in anor …
This narrative review critically explores the role of N-methyl-D-aspartate receptor-mediated excitatory and inhibitory neurometabolit …
Thermogenic adipocyte-derived zinc promotes sympathetic innervation in male mice.
Jiang J, Zhou D, Zhang A, Yu W, Du L, Yuan H, Zhang C, Wang Z, Jia X, Zhang ZN, Luan B. Jiang J, et al. Nat Metab. 2023 Mar;5(3):481-494. doi: 10.1038/s42255-023-00751-9. Epub 2023 Mar 6. Nat Metab. 2023. PMID: 36879120
Sympathetic neurons activate thermogenic adipocytes through release of catecholamine; however, the regulation of sympathetic innervation by thermogenic adipocytes is unclear. Here, we identify primary zinc ion (Zn) as a thermogenic adipocyte-secreted factor that promotes s …
Sympathetic neurons activate thermogenic adipocytes through release of catecholamine; however, the regulation of sympathetic innervation by …
Interactions between Zinc and Allosteric Modulators of the Glycine Receptor.
Cornelison GL, Daszkowski AW, Pflanz NC, Mihic SJ. Cornelison GL, et al. J Pharmacol Exp Ther. 2017 Apr;361(1):1-8. doi: 10.1124/jpet.116.239152. Epub 2017 Jan 13. J Pharmacol Exp Ther. 2017. PMID: 28087784 Free PMC article.
This suggests that, unless accounted for, previous studies of glycine receptor modulation were measuring the effects of modulator plus comodulation by zinc on receptor function. ...We investigated the utility of previously described "zinc-enhancement-i …
This suggests that, unless accounted for, previous studies of glycine receptor modulation were measuring the effects of modulator plu …
Zinc Ameliorates Nogo-A Receptor and Osteocalcin Gene Expression in Memory-Sensitive Rat Hippocampus Impaired by Intracerebroventricular Injection of Streptozotocin.
Gumus H, Baltaci SB, Unal O, Gulbahce-Mutlu E, Mogulkoc R, Baltaci AK. Gumus H, et al. Biol Trace Elem Res. 2023 Jul;201(7):3381-3386. doi: 10.1007/s12011-022-03410-4. Epub 2022 Sep 3. Biol Trace Elem Res. 2023. PMID: 36057764
Zinc supplementation attenuated the increase in hippocampal Nogo-A receptor gene expression, which was significantly increased in zinc deficiency. ...These results are the first to examine the effect of zinc deficiency and supplementation on hippocampa
Zinc supplementation attenuated the increase in hippocampal Nogo-A receptor gene expression, which was significantly increased
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