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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 2
2000 1
2001 3
2002 4
2003 5
2004 14
2005 6
2006 7
2007 7
2008 11
2009 11
2010 14
2011 6
2012 8
2013 5
2014 10
2015 13
2016 6
2017 6
2018 3
2019 6
2020 4
2021 6
2022 5
2023 9
2024 6

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167 results

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Page 1
Real-world effectiveness of molnupiravir and nirmatrelvir plus ritonavir against mortality, hospitalisation, and in-hospital outcomes among community-dwelling, ambulatory patients with confirmed SARS-CoV-2 infection during the omicron wave in Hong Kong: an observational study.
Wong CKH, Au ICH, Lau KTK, Lau EHY, Cowling BJ, Leung GM. Wong CKH, et al. Lancet. 2022 Oct 8;400(10359):1213-1222. doi: 10.1016/S0140-6736(22)01586-0. Lancet. 2022. PMID: 36216007 Free PMC article.
We identified patients with COVID-19 who received either molnupiravir (800 mg twice daily for 5 days) or nirmatrelvir plus ritonavir (nirmatrelvir 300 mg and ritonavir 100 mg twice daily for 5 days, or nirmatrelvir 150 mg and ritonavir 100 mg if estima …
We identified patients with COVID-19 who received either molnupiravir (800 mg twice daily for 5 days) or nirmatrelvir plus ritonavir (nirmat …
Nirmatrelvir/Ritonavir for hemodialysis patients with COVID-19.
Lu J, Cai H, Hao Y, Lin Z, Liu S, Zhan Y, Ding L, Huang M, Li Z, Xu L, Yan X, Yang L, Zhang H, Zhang W, Zhao L, Zhao J, Wang T, Gu L. Lu J, et al. Front Pharmacol. 2023 May 12;14:1161897. doi: 10.3389/fphar.2023.1161897. eCollection 2023. Front Pharmacol. 2023. PMID: 37251313 Free PMC article.
Participants were treated with nirmatrelvir 150 mg or 300 mg once a day (another 75 mg or 150 mg supplied after hemodialysis) and ritonavir 100 mg twice daily for 5 days, respectively. The primary outcome was the safety of nirmatrelvir/ritonavir, including the Cmin …
Participants were treated with nirmatrelvir 150 mg or 300 mg once a day (another 75 mg or 150 mg supplied after hemodialysis) and ritonav …
Pharmacokinetics of docetaxel and ritonavir after oral administration of ModraDoc006/r in patients with prostate cancer versus patients with other advanced solid tumours.
Vermunt MAC, van der Heijden LT, Hendrikx JJMA, Schinkel AH, de Weger VA, van der Putten E, van Triest B, Bergman AM, Beijnen JH. Vermunt MAC, et al. Cancer Chemother Pharmacol. 2021 Jun;87(6):855-869. doi: 10.1007/s00280-021-04259-5. Epub 2021 Mar 20. Cancer Chemother Pharmacol. 2021. PMID: 33744986
METHODS: The docetaxel and ritonavir PK were compared between four patient groups from three clinical phase I trials, including eight male and eight female patients with different types of solid tumours (study 1), seven patients with HSPC (study 2) and five patients with mCRPC (s …
METHODS: The docetaxel and ritonavir PK were compared between four patient groups from three clinical phase I trials, including eight male a …
Effect of low-dose ritonavir (100 mg twice daily) on the activity of cytochrome P450 2D6 in healthy volunteers.
Aarnoutse RE, Kleinnijenhuis J, Koopmans PP, Touw DJ, Wieling J, Hekster YA, Burger DM. Aarnoutse RE, et al. Clin Pharmacol Ther. 2005 Dec;78(6):664-74. doi: 10.1016/j.clpt.2005.09.001. Clin Pharmacol Ther. 2005. PMID: 16338282 Clinical Trial.
RESULTS: Low-dose ritonavir (100 mg twice daily) significantly increased the exposure to single-dose desipramine, as reflected in a geometric mean ratio (with ritonavir/without ritonavir) of 1.26 (95% confidence interval, 1.13-1.40) for the desipramine area under th …
RESULTS: Low-dose ritonavir (100 mg twice daily) significantly increased the exposure to single-dose desipramine, as reflected …
Effects of nirmatrelvir/ritonavir on midazolam and dabigatran pharmacokinetics in healthy participants.
Cox DS, Rehman M, Khan T, Ginman K, Salageanu J, LaBadie RR, Wan K, Damle B. Cox DS, et al. Br J Clin Pharmacol. 2023 Nov;89(11):3352-3363. doi: 10.1111/bcp.15835. Epub 2023 Jul 12. Br J Clin Pharmacol. 2023. PMID: 37354048
Single oral doses of midazolam 2 mg (n = 12) or dabigatran 75 mg (n = 24) were administered alone and after steady state (i.e. 2 days) of nirmatrelvir/ritonavir 300 mg/100 mg and ritonavir 100 mg. Midazolam and dabigatran plasma concentrations and adverse events wer …
Single oral doses of midazolam 2 mg (n = 12) or dabigatran 75 mg (n = 24) were administered alone and after steady state (i.e. 2 days) of ni …
Heat-stable ritonavir tablets: a new formulation of a pharmacokinetic enhancer for HIV.
Sherman EM, Steinberg JG. Sherman EM, et al. Expert Opin Pharmacother. 2011 Jan;12(1):141-8. doi: 10.1517/14656566.2011.542151. Epub 2010 Dec 10. Expert Opin Pharmacother. 2011. PMID: 21142696 Review.
AREAS COVERED IN THIS REVIEW: The goal of this article is to review the ritonavir 100 mg heat-stable tablet formulation for the treatment of HIV, focusing on recent pharmacokinetic studies, safety and tolerability data, administration, and storage. ...
AREAS COVERED IN THIS REVIEW: The goal of this article is to review the ritonavir 100 mg heat-stable tablet formulation for th …
Lack of an Effect of Ritonavir Alone and Lopinavir-Ritonavir on the Pharmacokinetics of Fenofibric Acid in Healthy Volunteers.
Gordon LA, Malati CY, Hadigan C, McLaughlin M, Alfaro RM, Calderón MM, Kovacs JA, Penzak SR. Gordon LA, et al. Pharmacotherapy. 2016 Jan;36(1):49-56. doi: 10.1002/phar.1682. Pharmacotherapy. 2016. PMID: 26799348 Free PMC article. Clinical Trial.
INTERVENTION: Subjects received a single oral dose of fenofibrate 145 mg during three study phases: before ritonavir administration, after 2 weeks of administration of ritonavir 100 mg twice/day, and after 2 weeks of administration of lopinavir 400 mg-ritonavir …
INTERVENTION: Subjects received a single oral dose of fenofibrate 145 mg during three study phases: before ritonavir administration, after 2 …
167 results