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36,541 results

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Page 1
Structural insights into nuclear transcription by eukaryotic DNA-dependent RNA polymerases.
Girbig M, Misiaszek AD, Müller CW. Girbig M, et al. Nat Rev Mol Cell Biol. 2022 Sep;23(9):603-622. doi: 10.1038/s41580-022-00476-9. Epub 2022 May 3. Nat Rev Mol Cell Biol. 2022. PMID: 35505252 Review.
The eukaryotic transcription apparatus synthesizes a staggering diversity of RNA molecules. The labour of nuclear gene transcription is, therefore, divided among multiple DNA-dependent RNA polymerases. ...Common to the three RNA polymerases is t …
The eukaryotic transcription apparatus synthesizes a staggering diversity of RNA molecules. The labour of nuclear gene transcription …
Structural insights into RNA polymerases of negative-sense RNA viruses.
Te Velthuis AJW, Grimes JM, Fodor E. Te Velthuis AJW, et al. Nat Rev Microbiol. 2021 May;19(5):303-318. doi: 10.1038/s41579-020-00501-8. Epub 2021 Jan 25. Nat Rev Microbiol. 2021. PMID: 33495561 Free PMC article. Review.
Replication and transcription of the viral genome is performed by ~250-450 kDa viral RNA-dependent RNA polymerases that also contain capping or cap-snatching activity. In this Review, we compare recent high-resolution X-ray and cryoelectron microscopy structu …
Replication and transcription of the viral genome is performed by ~250-450 kDa viral RNA-dependent RNA polymerases that …
Eukaryotic RNA polymerases.
Sentenac A. Sentenac A. CRC Crit Rev Biochem. 1985;18(1):31-90. doi: 10.3109/10409238509082539. CRC Crit Rev Biochem. 1985. PMID: 3893883 Review.
This review will attempt to cover the present information on the multiple forms of eukaryotic DNA-dependent RNA polymerases, both at the structural and functional level. Nuclear RNA polymerases constitute a group of three large multimeric enzymes, each …
This review will attempt to cover the present information on the multiple forms of eukaryotic DNA-dependent RNA polymerases, b …
Multisubunit RNA polymerases.
Cramer P. Cramer P. Curr Opin Struct Biol. 2002 Feb;12(1):89-97. doi: 10.1016/s0959-440x(02)00294-4. Curr Opin Struct Biol. 2002. PMID: 11839495 Review.
Transcription of the genetic information in all cells is carried out by multisubunit RNA polymerases (RNAPs). Comparison of the crystal structures of a bacterial and a eukaryotic RNAP reveals a conserved core that comprises the active site and a multifunctional clam …
Transcription of the genetic information in all cells is carried out by multisubunit RNA polymerases (RNAPs). Comparison of th …
DNA-dependent RNA polymerases in plants.
Yang DL, Huang K, Deng D, Zeng Y, Wang Z, Zhang Y. Yang DL, et al. Plant Cell. 2023 Sep 27;35(10):3641-3661. doi: 10.1093/plcell/koad195. Plant Cell. 2023. PMID: 37453082 Free PMC article.
DNA-dependent RNA polymerases (Pols) transfer the genetic information stored in genomic DNA to RNA in all organisms. ...
DNA-dependent RNA polymerases (Pols) transfer the genetic information stored in genomic DNA to RNA in all organisms. .. …
Structures and Mechanisms of Nonsegmented, Negative-Strand RNA Virus Polymerases.
Ouizougun-Oubari M, Fearns R. Ouizougun-Oubari M, et al. Annu Rev Virol. 2023 Sep 29;10(1):199-215. doi: 10.1146/annurev-virology-111821-102603. Epub 2023 May 3. Annu Rev Virol. 2023. PMID: 37137281 Free article. Review.
The nonsegmented, negative-strand RNA viruses (nsNSVs), also known as the order Mononegavirales, have a genome consisting of a single strand of negative-sense RNA. ...To perform the different steps that are necessary for these processes, the nsNSV polymerases …
The nonsegmented, negative-strand RNA viruses (nsNSVs), also known as the order Mononegavirales, have a genome consisting of a single …
Charting the landscape of RNA polymerases to unleash their potential in strain improvement.
Wang Y, Li Q, Tian P, Tan T. Wang Y, et al. Biotechnol Adv. 2022 Jan-Feb;54:107792. doi: 10.1016/j.biotechadv.2021.107792. Epub 2021 Jun 30. Biotechnol Adv. 2022. PMID: 34216775 Review.
However, only modification of a small number of enzymes in most cases cannot maximize desired metabolites, and global regulation is required. Of myriad enzymes influencing global regulation, RNA polymerase (RNAP) may be the most versatile enzyme in biological realm because …
However, only modification of a small number of enzymes in most cases cannot maximize desired metabolites, and global regulation is required …
Structure and Function of RNA Polymerases and the Transcription Machineries.
Griesenbeck J, Tschochner H, Grohmann D. Griesenbeck J, et al. Subcell Biochem. 2017;83:225-270. doi: 10.1007/978-3-319-46503-6_9. Subcell Biochem. 2017. PMID: 28271479 Review.
In bacteria, archaea and eukaryotes, transcription is carried out by multi-subunit RNA polymerases (RNAPs) sharing a conserved architecture of the RNAP core. ...Another section will focus on transcription factors and their role in regulating the RNA polymeras …
In bacteria, archaea and eukaryotes, transcription is carried out by multi-subunit RNA polymerases (RNAPs) sharing a conserved …
Eukaryotic RNA polymerases.
Blair DG. Blair DG. Comp Biochem Physiol B. 1988;89(4):647-70. doi: 10.1016/0305-0491(88)90306-9. Comp Biochem Physiol B. 1988. PMID: 3288436 Review. No abstract available.
Multisubunit DNA-Dependent RNA Polymerases from Vaccinia Virus and Other Nucleocytoplasmic Large-DNA Viruses: Impressions from the Age of Structure.
Mirzakhanyan Y, Gershon PD. Mirzakhanyan Y, et al. Microbiol Mol Biol Rev. 2017 Jul 12;81(3):e00010-17. doi: 10.1128/MMBR.00010-17. Print 2017 Sep. Microbiol Mol Biol Rev. 2017. PMID: 28701329 Free PMC article. Review.
The past 17 years have been marked by a revolution in our understanding of cellular multisubunit DNA-dependent RNA polymerases (MSDDRPs) at the structural level. A parallel development over the past 15 years has been the emerging story of the giant viruses, which en …
The past 17 years have been marked by a revolution in our understanding of cellular multisubunit DNA-dependent RNA polymerases …
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