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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1979 1
1980 7
1981 13
1982 7
1983 17
1984 19
1985 18
1986 20
1987 23
1988 35
1989 53
1990 30
1991 43
1992 53
1993 76
1994 66
1995 80
1996 93
1997 86
1998 89
1999 124
2000 118
2001 103
2002 86
2003 81
2004 74
2005 69
2006 71
2007 74
2008 54
2009 65
2010 78
2011 77
2012 68
2013 74
2014 66
2015 61
2016 75
2017 57
2018 60
2019 47
2020 91
2021 63
2022 67
2023 68
2024 25

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Search Results

2,536 results

Results by year

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Page 1
Infantile Spasms: Outcome in Clinical Studies.
Riikonen R. Riikonen R. Pediatr Neurol. 2020 Jul;108:54-64. doi: 10.1016/j.pediatrneurol.2020.01.015. Epub 2020 Feb 4. Pediatr Neurol. 2020. PMID: 32305143 Review.
This review is based mainly on prospective studies and emphasizes data about the current first-line drugs, adrenocorticotropic hormone, vigabatrin, and prednisolone, taking into account the proportion of patients with known and unknown etiology, which has a very strong eff …
This review is based mainly on prospective studies and emphasizes data about the current first-line drugs, adrenocorticotropic hormone, v …
[Infantile spasms].
Préel M, Møller RS, Miranda MJ, Hoei-Hansen CE. Préel M, et al. Ugeskr Laeger. 2020 Apr 6;182(15):V10190597. Ugeskr Laeger. 2020. PMID: 32286217 Free article. Review. Danish.
Treatment varies among centres, and initial treatment may include vigabatrin and/or corticosteroids. In recent years, as summarised in this review, knowledge has substantially increased regarding genetic aetiologies and treatment regimens....
Treatment varies among centres, and initial treatment may include vigabatrin and/or corticosteroids. In recent years, as summarised i …
Vigabatrin.
Lewis H, Wallace SJ. Lewis H, et al. Dev Med Child Neurol. 2001 Dec;43(12):833-5. doi: 10.1017/s0012162201001517. Dev Med Child Neurol. 2001. PMID: 11769271 Free article. Review. No abstract available.
Vigabatrin.
Wheless JW, Ramsay RE, Collins SD. Wheless JW, et al. Neurotherapeutics. 2007 Jan;4(1):163-72. doi: 10.1016/j.nurt.2006.11.008. Neurotherapeutics. 2007. PMID: 17199033 Free PMC article. Review.
Early identification of potentially effective pharmacotherapy agents is important. Vigabatrin has been shown to be a generally well tolerated and effective antiepileptic drug (AED) in a wide variety of seizure types affecting both children and adults, particularly those wi …
Early identification of potentially effective pharmacotherapy agents is important. Vigabatrin has been shown to be a generally well t …
Overview of therapeutic options for epilepsy.
Kuchenbuch M, Chiron C, Milh M. Kuchenbuch M, et al. Arch Pediatr. 2022 Dec;29(5S):5S14-5S19. doi: 10.1016/S0929-693X(22)00285-8. Arch Pediatr. 2022. PMID: 36585066 Review.
As for epilepsy of other causes, therapeutic options depend on the type of seizure/epilepsy, age and drug resistance, but there are significant specificities for TSC. (1) As first-line treatment, vigabatrin is unanimously recommended for infantile spasms and focal seizures …
As for epilepsy of other causes, therapeutic options depend on the type of seizure/epilepsy, age and drug resistance, but there are signific …
Epilepsy (partial).
Maguire M, Marson AG, Ramaratnam S. Maguire M, et al. BMJ Clin Evid. 2011 May 6;2011:1214. BMJ Clin Evid. 2011. PMID: 21549021 Free PMC article. Review.
CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: antiepileptic drugs after a single seizure; monotherapy for partial epilepsy using carbamazepine, gabapentin, lamotrigine, levetiracetam, phenoba …
CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: antie …
Safety and effectiveness of hormonal treatment versus hormonal treatment with vigabatrin for infantile spasms (ICISS): a randomised, multicentre, open-label trial.
O'Callaghan FJ, Edwards SW, Alber FD, Hancock E, Johnson AL, Kennedy CR, Likeman M, Lux AL, Mackay M, Mallick AA, Newton RW, Nolan M, Pressler R, Rating D, Schmitt B, Verity CM, Osborne JP; participating investigators. O'Callaghan FJ, et al. Lancet Neurol. 2017 Jan;16(1):33-42. doi: 10.1016/S1474-4422(16)30294-0. Epub 2016 Nov 10. Lancet Neurol. 2017. PMID: 27838190 Free article. Clinical Trial.
Serious adverse reactions necessitating hospitalisation occurred in 33 infants (16 on hormonal therapy alone and 17 on hormonal therapy with vigabatrin). The most common serious adverse reaction was infection occurring in five infants on hormonal therapy alone and four on …
Serious adverse reactions necessitating hospitalisation occurred in 33 infants (16 on hormonal therapy alone and 17 on hormonal therapy with …
The United Kingdom Infantile Spasms Study (UKISS) comparing hormone treatment with vigabatrin on developmental and epilepsy outcomes to age 14 months: a multicentre randomised trial.
Lux AL, Edwards SW, Hancock E, Johnson AL, Kennedy CR, Newton RW, O'Callaghan FJ, Verity CM, Osborne JP; United Kingdom Infantile Spasms Study. Lux AL, et al. Lancet Neurol. 2005 Nov;4(11):712-7. doi: 10.1016/S1474-4422(05)70199-X. Lancet Neurol. 2005. PMID: 16239177 Clinical Trial.
Absence of spasms at final clinical assessment (hormone 41/55 [75%] vs vigabatrin 39/51 [76%]) was similar in each treatment group (difference 1.9%, 95% CI -18.3% to 14.4%; chi(2)=0.05; p=0.82). Mean VABS score did not differ significantly (hormone 78.6 [SD 16.8] vs vig …
Absence of spasms at final clinical assessment (hormone 41/55 [75%] vs vigabatrin 39/51 [76%]) was similar in each treatment group (d …
Vigabatrin.
French JA. French JA. Epilepsia. 1999;40 Suppl 5:S11-6. doi: 10.1111/j.1528-1157.1999.tb00914.x. Epilepsia. 1999. PMID: 10530689 Free article. Review.
Vigabatrin (VGB) is a structural analogue of the inhibitory neurotransmitter gamma-amino butyric acid (GABA), which produces its antiepileptic effect by irreversibly inhibiting the degradative enzyme GABA-transaminase. ...Recently, safety issues have been raised with regar …
Vigabatrin (VGB) is a structural analogue of the inhibitory neurotransmitter gamma-amino butyric acid (GABA), which produces its anti …
New antiepileptic drugs.
Vajda FJ. Vajda FJ. J Clin Neurosci. 2000 Mar;7(2):88-101. doi: 10.1054/jocn.1999.0157. J Clin Neurosci. 2000. PMID: 10844790 Review. No abstract available.
2,536 results