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Sceletium tortuosum: A review on its phytochemistry, pharmacokinetics, biological and clinical activities.
Olatunji TL, Siebert F, Adetunji AE, Harvey BH, Gericke J, Hamman JH, Van der Kooy F. Olatunji TL, et al. J Ethnopharmacol. 2021 Nov 15;280:114476. doi: 10.1016/j.jep.2021.114476. Epub 2021 Jul 30. J Ethnopharmacol. 2021. PMID: 34333104 Review.
ETHNOPHARMACOLOGICAL RELEVANCE: Sceletium tortuosum (L.) N.E.Br, the most sought after and widely researched species in the genus Sceletium is a succulent forb endemic to South Africa. ...RESULTS: Twenty-five alkaloids belonging to four structural classes viz …
ETHNOPHARMACOLOGICAL RELEVANCE: Sceletium tortuosum (L.) N.E.Br, the most sought after and widely researched species in the ge …
Sceletium tortuosum: A review on its phytochemistry, pharmacokinetics, biological, pre-clinical and clinical activities.
Olatunji TL, Siebert F, Adetunji AE, Harvey BH, Gericke J, Hamman JH, Van der Kooy F. Olatunji TL, et al. J Ethnopharmacol. 2022 Apr 6;287:114711. doi: 10.1016/j.jep.2021.114711. Epub 2021 Nov 8. J Ethnopharmacol. 2022. PMID: 34758918
ETHNOPHARMACOLOGICAL RELEVANCE: Sceletium tortuosum (L.) N.E.Br., the most sought after and widely researched species in the genus Sceletium is a succulent forb endemic to South Africa. ...Nevertheless, the aforementioned studies have demonstrated that S. …
ETHNOPHARMACOLOGICAL RELEVANCE: Sceletium tortuosum (L.) N.E.Br., the most sought after and widely researched species in the g …
The effects of Sceletium tortuosum (L.) N.E. Br. extract fraction in the chick anxiety-depression model.
Carpenter JM, Jourdan MK, Fountain EM, Ali Z, Abe N, Khan IA, Sufka KJ. Carpenter JM, et al. J Ethnopharmacol. 2016 Dec 4;193:329-332. doi: 10.1016/j.jep.2016.08.019. Epub 2016 Aug 20. J Ethnopharmacol. 2016. PMID: 27553978
ETHNOPHARMACOLOGICAL RELEVANCE: Sceletium tortuosum (L.) N.E. Br. has been reported to elevate mood, reduce anxiety and stress and alleviate pain. ...Imipramine, but not S. tortuosum groups, increased DVoc rates in the depression phase indicative of an …
ETHNOPHARMACOLOGICAL RELEVANCE: Sceletium tortuosum (L.) N.E. Br. has been reported to elevate mood, reduce anxiety and stress …
Immunomodulatory effects of Sceletium tortuosum (Trimesemine) elucidated in vitro: Implications for chronic disease.
Bennett AC, Smith C. Bennett AC, et al. J Ethnopharmacol. 2018 Mar 25;214:134-140. doi: 10.1016/j.jep.2017.12.020. Epub 2017 Dec 16. J Ethnopharmacol. 2018. PMID: 29253615
ETHNOPHARMACOLOGICAL RELEVANCE: Sceletium tortuosum, among other Sceletium species, was traditionally used by the Khoisan people of Southern Africa for relief of pain-related ailments. ...These findings indicate that Sceletium may be beneficial for the …
ETHNOPHARMACOLOGICAL RELEVANCE: Sceletium tortuosum, among other Sceletium species, was traditionally used by the Khois …
A Chewable Cure "Kanna": Biological and Pharmaceutical Properties of Sceletium tortuosum.
Manganyi MC, Bezuidenhout CC, Regnier T, Ateba CN. Manganyi MC, et al. Molecules. 2021 Apr 28;26(9):2557. doi: 10.3390/molecules26092557. Molecules. 2021. PMID: 33924742 Free PMC article. Review.
Sceletium tortuosum (L.) N.E.Br. (Mesembryanthemaceae), commonly known as kanna or kougoed, is an effective indigenous medicinal plant in South Africa, specifically to the native San and Khoikhoi tribes. ...Various studies have revealed that extracts of the plant ha …
Sceletium tortuosum (L.) N.E.Br. (Mesembryanthemaceae), commonly known as kanna or kougoed, is an effective indigenous medicin …
Effects of Sceletium tortuosum in rats.
Loria MJ, Ali Z, Abe N, Sufka KJ, Khan IA. Loria MJ, et al. J Ethnopharmacol. 2014 Aug 8;155(1):731-5. doi: 10.1016/j.jep.2014.06.007. Epub 2014 Jun 12. J Ethnopharmacol. 2014. PMID: 24930358
This study sought to more broadly characterize activity of Sceletium tortuosum and mesembrine in a number of common, rodent-based assays that model nociception, depression, anxiety, ataxia, and abuse liability. ...The Sceletium tortuosum fractio …
This study sought to more broadly characterize activity of Sceletium tortuosum and mesembrine in a number of common, rodent-ba …
Formulation of Medicated Chewing Gum Containing Sceletium tortuosum and Process Optimization Utilizing the SeDeM Diagram Expert System.
Viljoen JM, van der Walt S, Hamman JH. Viljoen JM, et al. AAPS PharmSciTech. 2021 Mar 12;22(3):102. doi: 10.1208/s12249-021-01961-8. AAPS PharmSciTech. 2021. PMID: 33712901
Sceletium tortuosum is one of the most promising medicinal plant species for treating anxiety and depression. ...This study intended formulating novel medicated chewing gum containing S. tortuosum to alleviate depression and anxiety. S. tortu …
Sceletium tortuosum is one of the most promising medicinal plant species for treating anxiety and depression. ...This s …
Sceletium for Managing Anxiety, Depression and Cognitive Impairment: A Traditional Herbal Medicine in Modern-Day Regulatory Systems.
Brendler T, Brinckmann JA, Feiter U, Gericke N, Lang L, Pozharitskaya ON, Shikov AN, Smith M, Wyk BV. Brendler T, et al. Curr Neuropharmacol. 2021;19(9):1384-1400. doi: 10.2174/1570159X19666210215124737. Curr Neuropharmacol. 2021. PMID: 33588735 Free PMC article.
This case study investigates and compares how a Southern African herbal medicine with great potential as an anxiolytic and mild antidepressant - Mesembryanthemum tortuosum L. [syn. Sceletium tortuosum (L.) N.E.Br.] aerial parts - fares internationally in toda …
This case study investigates and compares how a Southern African herbal medicine with great potential as an anxiolytic and mild antidepressa …
The effects of Sceletium tortuosum in an in vivo model of psychological stress.
Smith C. Smith C. J Ethnopharmacol. 2011 Jan 7;133(1):31-6. doi: 10.1016/j.jep.2010.08.058. Epub 2010 Sep 17. J Ethnopharmacol. 2011. PMID: 20816940
AIM OF THE STUDY: Sceletium, and especially Sceletium tortuosum, is traditionally used as masticator and thought to have a sedative effect which may be beneficial to reduce symptoms of anxiety and/or depression. ...MATERIALS AND METHODS: Male Wistar ra …
AIM OF THE STUDY: Sceletium, and especially Sceletium tortuosum, is traditionally used as masticator and thought to hav …
Mesembryanthemum tortuosum L. alkaloids modify anxiety-like behaviour in a zebrafish model.
Maphanga VB, Skalicka-Wozniak K, Budzynska B, Skiba A, Chen W, Agoni C, Enslin GM, Viljoen AM. Maphanga VB, et al. J Ethnopharmacol. 2022 May 23;290:115068. doi: 10.1016/j.jep.2022.115068. Epub 2022 Feb 5. J Ethnopharmacol. 2022. PMID: 35134486
ETHNOPHARMACOLOGICAL RELEVANCE: Mesembryanthemum tortuosum L. (previously known as Sceletium tortuosum (L.) N.E. Br.) is indigenous to South Africa and traditionally used to alleviate anxiety, stress and depression. Mesembrine and its alkaloid analogue …
ETHNOPHARMACOLOGICAL RELEVANCE: Mesembryanthemum tortuosum L. (previously known as Sceletium tortuosum (L.) N.E. Br.) i …
20 results