Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 2
1982 1
1983 4
1984 1
1985 2
1986 2
1987 3
1988 2
1989 3
1990 2
1991 4
1993 6
1994 4
1995 4
1996 6
1997 4
1998 6
1999 5
2000 5
2001 5
2002 9
2003 8
2004 11
2005 8
2006 4
2007 3
2008 3
2009 4
2010 2
2011 4
2012 3
2013 4
2014 6
2015 8
2016 7
2017 7
2018 3
2019 5
2020 5
2021 7
2022 1
2023 7
2024 2

Text availability

Article attribute

Article type

Publication date

Search Results

183 results

Results by year

Filters applied: . Clear all
Page 1
Regulatory T cells control Staphylococcus aureus and disease severity of cutaneous leishmaniasis.
Singh TP, Farias Amorim C, Lovins VM, Bradley CW, Carvalho LP, Carvalho EM, Grice EA, Scott P. Singh TP, et al. Among authors: scott p. J Exp Med. 2023 Dec 4;220(12):e20230558. doi: 10.1084/jem.20230558. Epub 2023 Oct 9. J Exp Med. 2023. PMID: 37812390 Free PMC article.
However, it is not known how these microbiota-driven immune responses are regulated. Here, we report that depletion of Foxp3+ regulatory T cells (Tregs) in Staphylococcus aureus-colonized mice resulted in less IL-17 and an IFN-gamma-dependent skin inflammation with …
However, it is not known how these microbiota-driven immune responses are regulated. Here, we report that depletion of Foxp3+ regulatory …
Memory T cells in cutaneous leishmaniasis.
Glennie ND, Scott P. Glennie ND, et al. Among authors: scott p. Cell Immunol. 2016 Nov;309:50-54. doi: 10.1016/j.cellimm.2016.07.010. Epub 2016 Jul 16. Cell Immunol. 2016. PMID: 27493096 Free PMC article. Review.
Following resolution of the disease, short-lived effector T cells, as well as long-lived central memory T cells and skin resident memory T cells, are retained and able to mediate immunity to a secondary infection. ...Since both central me …
Following resolution of the disease, short-lived effector T cells, as well as long-lived central memory T cells …
Cutaneous leishmaniasis: immune responses in protection and pathogenesis.
Scott P, Novais FO. Scott P, et al. Nat Rev Immunol. 2016 Sep;16(9):581-92. doi: 10.1038/nri.2016.72. Epub 2016 Jul 18. Nat Rev Immunol. 2016. PMID: 27424773 Review.
Nevertheless, advances in our knowledge of the cells that participate in protection against Leishmania infection and the cells that mediate increased pathology have highlighted new approaches for vaccine development and immunotherapy. In this Review, we discuss the early e …
Nevertheless, advances in our knowledge of the cells that participate in protection against Leishmania infection and the cells that m …
CD8+ T cells in cutaneous leishmaniasis: the good, the bad, and the ugly.
Novais FO, Scott P. Novais FO, et al. Among authors: scott p. Semin Immunopathol. 2015 May;37(3):251-9. doi: 10.1007/s00281-015-0475-7. Epub 2015 Mar 24. Semin Immunopathol. 2015. PMID: 25800274 Free PMC article. Review.
In leishmaniasis, a disease caused by intracellular protozoan parasites of the genus Leishmania, CD8(+) T cells have been shown to be protective. However, increasing evidence indicates that CD8(+) T cells may also exacerbate disease. In this rev …
In leishmaniasis, a disease caused by intracellular protozoan parasites of the genus Leishmania, CD8(+) T cells have be …
Long-Lived Skin-Resident Memory T Cells Contribute to Concomitant Immunity in Cutaneous Leishmaniasis.
Scott P. Scott P. Cold Spring Harb Perspect Biol. 2020 Oct 1;12(10):a038059. doi: 10.1101/cshperspect.a038059. Cold Spring Harb Perspect Biol. 2020. PMID: 32839202 Free PMC article. Review.
One set of protective T cells are short-lived effector T cells requiring constant stimulation, which would be difficult to maintain by vaccination. However, parasite-independent memory T cells, including central memory T cells …
One set of protective T cells are short-lived effector T cells requiring constant stimulation, which would be di …
Host-Directed Therapies for Cutaneous Leishmaniasis.
Novais FO, Amorim CF, Scott P. Novais FO, et al. Among authors: scott p. Front Immunol. 2021 Mar 26;12:660183. doi: 10.3389/fimmu.2021.660183. eCollection 2021. Front Immunol. 2021. PMID: 33841444 Free PMC article. Review.
Leishmaniasis: complexity at the host-pathogen interface.
Kaye P, Scott P. Kaye P, et al. Among authors: scott p. Nat Rev Microbiol. 2011 Jul 11;9(8):604-15. doi: 10.1038/nrmicro2608. Nat Rev Microbiol. 2011. PMID: 21747391 Review.
Leishmania is a genus of protozoan parasites that are transmitted by the bite of phlebotomine sandflies and give rise to a range of diseases (collectively known as leishmaniases) that affect over 150 million people worldwide. Cellular immune mechanisms have a major role in …
Leishmania is a genus of protozoan parasites that are transmitted by the bite of phlebotomine sandflies and give rise to a range of d …
Skin-resident CD4+ T cells protect against Leishmania major by recruiting and activating inflammatory monocytes.
Glennie ND, Volk SW, Scott P. Glennie ND, et al. Among authors: scott p. PLoS Pathog. 2017 Apr 18;13(4):e1006349. doi: 10.1371/journal.ppat.1006349. eCollection 2017 Apr. PLoS Pathog. 2017. PMID: 28419151 Free PMC article.
In this study we addressed this issue with a population of protective skin-resident, IFNgamma-producing CD4+ memory T cells generated following Leishmania major infection. We previously found that resident memory T cells recruit circulating effe …
In this study we addressed this issue with a population of protective skin-resident, IFNgamma-producing CD4+ memory T cells ge …
Multiomic profiling of cutaneous leishmaniasis infections reveals microbiota-driven mechanisms underlying disease severity.
Farias Amorim C, Lovins VM, Singh TP, Novais FO, Harris JC, Lago AS, Carvalho LP, Carvalho EM, Beiting DP, Scott P, Grice EA. Farias Amorim C, et al. Among authors: scott p. Sci Transl Med. 2023 Oct 18;15(718):eadh1469. doi: 10.1126/scitranslmed.adh1469. Epub 2023 Oct 18. Sci Transl Med. 2023. PMID: 37851822 Free PMC article.
Leishmania braziliensis is a parasitic infection that can result in inflammation and skin injury with highly variable and unpredictable clinical outcomes. ...
Leishmania braziliensis is a parasitic infection that can result in inflammation and skin injury with highly variable and unpredictab …
Skin-resident memory CD4+ T cells enhance protection against Leishmania major infection.
Glennie ND, Yeramilli VA, Beiting DP, Volk SW, Weaver CT, Scott P. Glennie ND, et al. Among authors: scott p. J Exp Med. 2015 Aug 24;212(9):1405-14. doi: 10.1084/jem.20142101. Epub 2015 Jul 27. J Exp Med. 2015. PMID: 26216123 Free PMC article.
Although circulating Leishmania-specific T cells are known to play a critical role in immunity, the role of memory T cells present in peripheral tissues has not been explored. Here, we identify a population of skin-resident Leishmania-spe …
Although circulating Leishmania-specific T cells are known to play a critical role in immunity, the role of memory T …
183 results