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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1979 1
1980 2
1981 1
1983 1
1985 2
1987 2
1988 1
1989 11
1990 5
1991 9
1992 7
1993 14
1994 6
1995 15
1996 14
1997 15
1998 18
1999 6
2000 5
2001 6
2002 8
2003 12
2004 4
2005 3
2006 8
2007 10
2008 3
2009 5
2010 7
2011 4
2012 4
2013 5
2014 6
2015 5
2016 1
2017 3
2018 5
2019 1
2020 4
2021 3
2022 3
2023 3
2024 0

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Search Results

240 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Efficacy and safety of selegiline across different psychiatric disorders: A systematic review and meta-analysis of oral and transdermal formulations.
Rossano F, Caiazza C, Sobrino A, Solini N, Vellucci A, Zotti N, Fornaro M, Gillman K, Cattaneo CI, Van den Eynde V, Birkenhager TK, Ruhé HG, Stahl S, Iasevoli F, de Bartolomeis A. Rossano F, et al. Eur Neuropsychopharmacol. 2023 Jul;72:60-78. doi: 10.1016/j.euroneuro.2023.03.012. Epub 2023 Apr 21. Eur Neuropsychopharmacol. 2023. PMID: 37087864
The present systematic review and meta-analysis appraises the evidence of different formulations/dosages of selegiline across different psychiatric conditions. We inquired PubMed/MEDLINE/Cochrane-Central/WHO-ICTRP/Clarivate-WebOfScience and the Chinese-Electronic-Journal D …
The present systematic review and meta-analysis appraises the evidence of different formulations/dosages of selegiline across differe …
Selegiline for Alzheimer's disease.
Birks J, Flicker L. Birks J, et al. Cochrane Database Syst Rev. 2003;(1):CD000442. doi: 10.1002/14651858.CD000442. Cochrane Database Syst Rev. 2003. PMID: 12535396 Review.
OBJECTIVES: The objective of this review is to assess whether or not selegiline improves the well-being of patients with Alzheimer's disease. ...There is little evidence of adverse effects caused by selegiline, and few withdrew from trials, apart from the Sano trial …
OBJECTIVES: The objective of this review is to assess whether or not selegiline improves the well-being of patients with Alzheimer's …
Comparison of selegiline and levodopa combination therapy versus levodopa monotherapy in the treatment of Parkinson's disease: a meta-analysis.
Jiang DQ, Li MX, Jiang LL, Chen XB, Zhou XW. Jiang DQ, et al. Aging Clin Exp Res. 2020 May;32(5):769-779. doi: 10.1007/s40520-019-01232-4. Epub 2019 Jun 7. Aging Clin Exp Res. 2020. PMID: 31175606 Review.
BACKGROUND: Selegiline or levodopa treatment has been suggested as a therapeutic method for Parkinson's disease (PD) in many clinical trial reports. ...The aim of this report was to evaluate the clinical efficacy and safety of selegiline plus levodopa (S + L) combin …
BACKGROUND: Selegiline or levodopa treatment has been suggested as a therapeutic method for Parkinson's disease (PD) in many clinical …
Selegiline in Parkinson's disease.
Teräväinen H. Teräväinen H. Acta Neurol Scand. 1990 Apr;81(4):333-6. doi: 10.1111/j.1600-0404.1990.tb01565.x. Acta Neurol Scand. 1990. PMID: 2113756 Clinical Trial.
The daily dose of selegiline was gradually increased to a maximum of 30 mg in all patients. The clinical neurological disability (Columbia score) was about 10% less on selegiline (30 mg/day) than on placebo. This difference was neither statistically nor clinically s …
The daily dose of selegiline was gradually increased to a maximum of 30 mg in all patients. The clinical neurological disability (Col …
Comparative efficacy and safety of monoamine oxidase type B inhibitors plus channel blockers and monoamine oxidase type B inhibitors as adjuvant therapy to levodopa in the treatment of Parkinson's disease: a network meta-analysis of randomized controlled trials.
Yan R, Cai H, Cui Y, Su D, Cai G, Lin F, Feng T. Yan R, et al. Eur J Neurol. 2023 Apr;30(4):1118-1134. doi: 10.1111/ene.15651. Epub 2022 Dec 11. Eur J Neurol. 2023. PMID: 36437702 Review.
METHOD: Randomized controlled trials enrolling PD patients treated with selegiline, rasagiline, safinamide or zonisamide as adjuvant therapy to levodopa were identified. ...Compared with levodopa monotherapy, the combination therapy of MAO-BIs and levodopa was significantl …
METHOD: Randomized controlled trials enrolling PD patients treated with selegiline, rasagiline, safinamide or zonisamide as adjuvant …
Pharmacological Management of Lewy Body Dementia: A Systematic Review and Meta-Analysis.
Stinton C, McKeith I, Taylor JP, Lafortune L, Mioshi E, Mak E, Cambridge V, Mason J, Thomas A, O'Brien JT. Stinton C, et al. Am J Psychiatry. 2015 Aug 1;172(8):731-42. doi: 10.1176/appi.ajp.2015.14121582. Epub 2015 Jun 18. Am J Psychiatry. 2015. PMID: 26085043 Free article. Review.
Descriptive summaries provide some evidence of benefits for galantamine, modafinil, levodopa, rotigotine, clozapine, duloxetine, clonazepam, ramelteon, gabapentin, zonisamide, and yokukansan. Piracetam, amantadine, selegiline, olanzapine, quetiapine, risperidone, and cital …
Descriptive summaries provide some evidence of benefits for galantamine, modafinil, levodopa, rotigotine, clozapine, duloxetine, clonazepam, …
Selegiline's neuroprotective capacity revisited.
Riederer P, Lachenmayer L. Riederer P, et al. J Neural Transm (Vienna). 2003 Nov;110(11):1273-8. doi: 10.1007/s00702-003-0083-x. J Neural Transm (Vienna). 2003. PMID: 14628191 No abstract available.
Selegiline pharmacokinetics are unaffected by the CYP3A4 inhibitor itraconazole.
Kivistö KT, Wang JS, Backman JT, Nyman L, Taavitsainen P, Anttila M, Neuvonen PJ. Kivistö KT, et al. Eur J Clin Pharmacol. 2001 Apr;57(1):37-42. doi: 10.1007/s002280100278. Eur J Clin Pharmacol. 2001. PMID: 11372588 Clinical Trial.
On day 4, a single 10-mg oral dose of selegiline hydrochloride was administered. Serum concentrations of selegiline and its primary metabolites desmethylselegiline and l-methamphetamine were determined up to 32 h. ...These findings suggest that selegiline is …
On day 4, a single 10-mg oral dose of selegiline hydrochloride was administered. Serum concentrations of selegiline and its pr …
Selegiline in ADHD adults: plasma monoamines and monoamine metabolites.
Ernst M, Liebenauer LL, Tebeka D, Jons PH, Eisenhofer G, Murphy DL, Zametkin AJ. Ernst M, et al. Neuropsychopharmacology. 1997 Apr;16(4):276-84. doi: 10.1016/S0893-133X(96)00243-6. Neuropsychopharmacology. 1997. PMID: 9094145 Clinical Trial.
Selegiline, at low dose, is a selective monoamine oxidase inhibitor type B (MAOI-B). After 2-week placebo baseline, 36 ADHD adults were randomized to 6-week placebo or 20 mg/day or 60 mg/day selegiline, followed by 2-week posttreatment placebo. Twenty-seven subjects …
Selegiline, at low dose, is a selective monoamine oxidase inhibitor type B (MAOI-B). After 2-week placebo baseline, 36 ADHD adults we …
Comparative effectiveness of dopamine agonists and monoamine oxidase type-B inhibitors for Parkinson's disease: a multiple treatment comparison meta-analysis.
Binde CD, Tvete IF, Gåsemyr JI, Natvig B, Klemp M. Binde CD, et al. Eur J Clin Pharmacol. 2020 Dec;76(12):1731-1743. doi: 10.1007/s00228-020-02961-6. Epub 2020 Jul 24. Eur J Clin Pharmacol. 2020. PMID: 32710141 Free PMC article.
METHODS: We performed a systematic literature search identifying randomized controlled trials investigating 4 dopamine agonists (cabergoline, pramipexole, ropinirole, rotigotine) and 3 MAO-B inhibitors (selegiline, rasagiline, safinamide) for Parkinson's disease. We extrac …
METHODS: We performed a systematic literature search identifying randomized controlled trials investigating 4 dopamine agonists (cabergoline …
240 results

Searches related to "selegiline"