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Convergent Strategy for the Synthesis of Oxa-, Thia-, and Selena[5]helicenes by Acetylene-Activated S(N)Ar Reactions.
Hoenig SM, Yan Y, Dougherty EA, Hudson R, Petovic S, Lee CK, Hu Y, Gomez LS, Katz JL. Hoenig SM, et al. J Org Chem. 2020 Mar 20;85(6):4553-4559. doi: 10.1021/acs.joc.0c00052. Epub 2020 Mar 12. J Org Chem. 2020. PMID: 32133863
A tandem acetylene-activated S(N)Ar-anionic cyclization strategy is presented for the synthesis of chalcogen-containing hetero[5]helicenes. Oxa-, thia-, and selena[5]helicenes are accessed from common ortho-fluoro-ethynylarene precursors, allowing the heteroatoms to be ins …
A tandem acetylene-activated S(N)Ar-anionic cyclization strategy is presented for the synthesis of chalcogen-containing hetero[5]helicenes. …
Celebrities influence on rheumatic diseases interest: a Google Trends analysis.
Kamiński M, Hrycaj P. Kamiński M, et al. Rheumatol Int. 2024 Mar;44(3):517-521. doi: 10.1007/s00296-023-05361-y. Epub 2023 Jun 14. Rheumatol Int. 2024. PMID: 37314496
Examples include Venus Williams with Sjogren's syndrome, Lady Gaga with fibromyalgia, Selena Gomez with lupus, Phil Mickelson with psoriatic arthritis, and Ashton Kutcher with vasculitis. ...
Examples include Venus Williams with Sjogren's syndrome, Lady Gaga with fibromyalgia, Selena Gomez with lupus, Phil Mickelson …
Multicenter lupus register from Argentina, the RELESSAR database: Influence of ethnicity on disease phenotype.
García MA, Alba P, Del Campo-Perez V, Roverano S, Quintana RM, Alvarez AP, Graf CE, Pisoni C, Spindler A, Gomez C, Figueredo HM, Papasidero S, Paniego R, de la Vega MC, Civit E, Gonzalez Lucero L, Martire MV, Aguila Maldonado R, Gordon S, Gobbi C, Micelli M, Nieto R, Rausch G, Gongora V, Damico A, Dubinsky D, Orden A, Zacariaz J, Romero J, Pera M, Goñi M, Rillo O, Baez R, Arturi V, Gonzalez A, Vivero F, Bedoya ME, Shmid MM, Caputo V, Larroude MS, Dominguez N, Gómez GN, Rodriguez GN, Marin J, Collado V, Jorfen M, Bedran Z, Curti A, Gazzoni MV, Sarano J, Zelaya M, Sacnun M, Finucci Curi P, Rojas Tessel R, Arias Saavedra M, Sattler ME, Machado Escobar MA, Astesana P, Paris U, Virasoro BM, Santa Cruz MJ, Allievi A, Vandale JM, Hojberg NG, Pons-Estel B. García MA, et al. Lupus. 2022 Apr;31(5):637-645. doi: 10.1177/09612033221083267. Lupus. 2022. PMID: 35382633
RELESSAR electronic database includes demographic, cumulative SLE manifestations, SELENA-SLEDAI, SLICC-SDI, Katz's severity and Charlson's comorbidity indexes and treatment patterns. ...Frequent manifestations were arthritis (83.5%), malar rash (79.5%), photosensitivity (7 …
RELESSAR electronic database includes demographic, cumulative SLE manifestations, SELENA-SLEDAI, SLICC-SDI, Katz's severity and Charl …
Global public interest in systemic lupus erythematosus: an investigation based on internet search data.
Wu GC, Cao F, Shen HH, Hu LQ, Hu Y, Sam NB. Wu GC, et al. Lupus. 2019 Oct;28(12):1435-1440. doi: 10.1177/0961203319878502. Epub 2019 Sep 25. Lupus. 2019. PMID: 31554457
RSV peaked in May and reached the trough in November. The top seven rising topics were Selena Gomez, Sjogren syndrome, autoimmunity, rheumatoid arthritis, rheumatology, antinuclear antibody and autoimmune disease. ...
RSV peaked in May and reached the trough in November. The top seven rising topics were Selena Gomez, Sjogren syndrome, autoimm …
Validation of an Argentine version of Lupus Quality of Life questionnaire.
Machado Escobar MA, Yacuzzi MS, Martinez RN, González Lucero L, Bellomio VI, Santana M, Galindo L, Mayer MM, Barreira JC, Sarano J, Gomez G, Collado MV, Martinez A, Orozco MC, Betancur G, Dal Pra F, Sanchez A, Juarez V, Lucero EV. Machado Escobar MA, et al. Lupus. 2016 Dec;25(14):1615-1622. doi: 10.1177/0961203316660202. Epub 2016 Jul 20. Lupus. 2016. PMID: 27444335
Demographic and socioeconomic variables were collected, as well as SELENA/SLEDAI, Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index Score, comorbidities and treatment data. ...RESULTS: Out of 147 patients, 93.2% were female, m …
Demographic and socioeconomic variables were collected, as well as SELENA/SLEDAI, Systemic Lupus International Collaborating Clinics/ …
Early B Cell and Plasma Cell Kinetics Upon Treatment Initiation Portend Flares in Systemic Lupus Erythematosus: A Post-Hoc Analysis of Three Phase III Clinical Trials of Belimumab.
Parodis I, Gomez A, Chow JW, Borg A, Lindblom J, Gatto M. Parodis I, et al. Front Immunol. 2022 Apr 4;13:796508. doi: 10.3389/fimmu.2022.796508. eCollection 2022. Front Immunol. 2022. PMID: 35444642 Free PMC article. Clinical Trial.
PATIENTS AND METHODS: Using data from the BLISS-76, BLISS-SC and BLISS Northeast Asia trials, we investigated associations of relative to baseline rapid (through week 8) and early (through week 24) changes in peripheral B cell subsets, anti-dsDNA and complement levels with the oc …
PATIENTS AND METHODS: Using data from the BLISS-76, BLISS-SC and BLISS Northeast Asia trials, we investigated associations of relative to ba …
Analysis of disease activity and response to treatment in a large Spanish cohort of patients with systemic lupus erythematosus.
Pego-Reigosa JM, Rúa-Figueroa Í, López-Longo FJ, Galindo-Izquierdo M, Calvo-Alén J, Olivé-Marqués A, del Campo V, García-Yébenes MJ, Loza-Santamaría E, Blanco R, Melero-González R, Vela-Casasempere P, Otón-Sánchez T, Tomero-Muriel E, Uriarte-Isacelaya E, Fito-Manteca MC, Freire-González M, Narváez J, Fernández-Nebro A, Zea-Mendoza A, Rosas J; RELESSER Group, from the Spanish Society of Rheumatology Systemic Autoimmune Diseases Study Group (EASSER). Pego-Reigosa JM, et al. Lupus. 2015 Jun;24(7):720-9. doi: 10.1177/0961203314563818. Epub 2014 Dec 15. Lupus. 2015. PMID: 25516473 Clinical Trial.
METHODS: We conducted a nationwide, retrospective, multicenter, cross-sectional cohort study of 3658 SLE patients. Data on demographics, disease characteristics: activity (SELENA-SLEDAI), damage, severity, hospitalizations and therapies were collected. ...At the time of th …
METHODS: We conducted a nationwide, retrospective, multicenter, cross-sectional cohort study of 3658 SLE patients. Data on demographics, dis …