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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1917 1
1945 1
1947 2
1948 1
1950 2
1951 1
1952 3
1953 1
1955 1
1956 1
1957 1
1958 3
1959 1
1960 1
1961 6
1962 2
1963 10
1964 13
1965 12
1966 15
1967 12
1968 16
1969 27
1970 16
1971 34
1972 27
1973 37
1974 33
1975 25
1976 37
1977 26
1978 20
1979 31
1980 32
1981 21
1982 32
1983 33
1984 32
1985 36
1986 44
1987 31
1988 40
1989 63
1990 49
1991 66
1992 60
1993 79
1994 66
1995 74
1996 54
1997 86
1998 95
1999 77
2000 65
2001 81
2002 106
2003 105
2004 134
2005 115
2006 148
2007 125
2008 133
2009 138
2010 151
2011 146
2012 160
2013 163
2014 156
2015 171
2016 198
2017 191
2018 235
2019 224
2020 285
2021 321
2022 310
2023 281
2024 129

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5,287 results

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Page 1
Sepsis-Induced Coagulopathy and Disseminated Intravascular Coagulation.
Iba T, Levi M, Levy JH. Iba T, et al. Semin Thromb Hemost. 2020 Feb;46(1):89-95. doi: 10.1055/s-0039-1694995. Epub 2019 Aug 23. Semin Thromb Hemost. 2020. PMID: 31443111 Review.
Disseminated intravascular coagulation (DIC) has been recognized as a deadly complication in sepsis, and its early recognition followed by appropriate management of the underlying infection are the current management strategies. ...In addition to activation of coagulation …
Disseminated intravascular coagulation (DIC) has been recognized as a deadly complication in sepsis, and its early recognition follow …
Endothelial dysfunction and immunothrombosis in sepsis.
Maneta E, Aivalioti E, Tual-Chalot S, Emini Veseli B, Gatsiou A, Stamatelopoulos K, Stellos K. Maneta E, et al. Front Immunol. 2023 Apr 4;14:1144229. doi: 10.3389/fimmu.2023.1144229. eCollection 2023. Front Immunol. 2023. PMID: 37081895 Free PMC article. Review.
Sepsis is a life-threatening clinical syndrome characterized by multiorgan dysfunction caused by a dysregulated or over-reactive host response to infection. ...Herein, we discuss the underlying mechanisms of organ-specific endothelial dysfunction and immunothrombosis in …
Sepsis is a life-threatening clinical syndrome characterized by multiorgan dysfunction caused by a dysregulated or over-reactive host …
Roles of Coagulation Abnormalities and Microthrombosis in Sepsis: Pathophysiology, Diagnosis, and Treatment.
Iba T, Umemura Y, Wada H, Levy JH. Iba T, et al. Arch Med Res. 2021 Nov;52(8):788-797. doi: 10.1016/j.arcmed.2021.07.003. Epub 2021 Jul 31. Arch Med Res. 2021. PMID: 34344558 Review.
However, recent advances in sepsis shed light on the role of coagulation disorders in the progression of sepsis. ...Although there is no globally agreed on anticoagulant therapy for DIC, the Japanese Surviving Sepsis Campaign Guidelines 2020 recommend using a …
However, recent advances in sepsis shed light on the role of coagulation disorders in the progression of sepsis. ...Although t …
Review: The Emerging Role of Neutrophil Extracellular Traps in Sepsis and Sepsis-Associated Thrombosis.
Chen Z, Zhang H, Qu M, Nan K, Cao H, Cata JP, Chen W, Miao C. Chen Z, et al. Front Cell Infect Microbiol. 2021 Mar 17;11:653228. doi: 10.3389/fcimb.2021.653228. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 33816356 Free PMC article. Review.
During the development of sepsis, neutrophils migrate from the circulating blood to infected tissues and mediate the formation of neutrophil extracellular traps (NETs) that kill pathogens. ...In this review, we will discuss the key role of neutrophils and NETs in …
During the development of sepsis, neutrophils migrate from the circulating blood to infected tissues and mediate the formation …
Inflammation and thrombosis: roles of neutrophils, platelets and endothelial cells and their interactions in thrombus formation during sepsis.
Iba T, Levy JH. Iba T, et al. J Thromb Haemost. 2018 Feb;16(2):231-241. doi: 10.1111/jth.13911. Epub 2017 Dec 21. J Thromb Haemost. 2018. PMID: 29193703 Free article. Review.
Recent research has also shed light on the critical role of thrombus formation, which prevents the dissemination of microorganisms. The cellular components of blood vessels, i.e. leukocytes, platelets, erythrocytes, and vascular endothelial cells, play significant roles in …
Recent research has also shed light on the critical role of thrombus formation, which prevents the dissemination of microorganisms. The cell …
Reduction of NETosis by targeting CXCR1/2 reduces thrombosis, lung injury, and mortality in experimental human and murine sepsis.
Alsabani M, Abrams ST, Cheng Z, Morton B, Lane S, Alosaimi S, Yu W, Wang G, Toh CH. Alsabani M, et al. Br J Anaesth. 2022 Feb;128(2):283-293. doi: 10.1016/j.bja.2021.10.039. Epub 2021 Dec 8. Br J Anaesth. 2022. PMID: 34893315 Free PMC article.
BACKGROUND: Neutrophil extracellular traps (NETs) facilitate bacterial clearance but also promote thrombosis and organ injury in sepsis. We quantified ex vivo NET induction in septic humans and murine models of sepsis to identify signalling pathways that may …
BACKGROUND: Neutrophil extracellular traps (NETs) facilitate bacterial clearance but also promote thrombosis and organ injury in s …
Sepsis and thrombosis.
Levi M, Schultz M, van der Poll T. Levi M, et al. Semin Thromb Hemost. 2013 Jul;39(5):559-66. doi: 10.1055/s-0033-1343894. Epub 2013 Apr 27. Semin Thromb Hemost. 2013. PMID: 23625756 Review.
Activation of coagulation frequently occurs in severe infection and sepsis and may contribute to the development of thrombosis. Coagulation abnormalities in sepsis range from a small decrease in platelet count and subclinical prolongation of global clotting t …
Activation of coagulation frequently occurs in severe infection and sepsis and may contribute to the development of thrombosis …
STING activation in platelets aggravates septic thrombosis by enhancing platelet activation and granule secretion.
Yang M, Jiang H, Ding C, Zhang L, Ding N, Li G, Zhang F, Wang J, Deng L, Liu J, Xu Y. Yang M, et al. Immunity. 2023 May 9;56(5):1013-1026.e6. doi: 10.1016/j.immuni.2023.02.015. Epub 2023 Mar 20. Immunity. 2023. PMID: 36944334 Free article.
Here, using the cecal ligation and puncture (CLP) model of sepsis, we observed septic thrombosis and neutrophil extracellular trap formation (NETosis) within the mouse vasculature by intravital microscopy. STING activation in platelets was a critical driver of se …
Here, using the cecal ligation and puncture (CLP) model of sepsis, we observed septic thrombosis and neutrophil extracellular …
Tissue Factor: An Essential Mediator of Hemostasis and Trigger of Thrombosis.
Grover SP, Mackman N. Grover SP, et al. Arterioscler Thromb Vasc Biol. 2018 Apr;38(4):709-725. doi: 10.1161/ATVBAHA.117.309846. Epub 2018 Feb 8. Arterioscler Thromb Vasc Biol. 2018. PMID: 29437578 Review.
In sepsis, inducible TF expression on monocytes leads to disseminated intravascular coagulation. ...This review will focus on the roles of TF in protective hemostasis and pathological thrombosis....
In sepsis, inducible TF expression on monocytes leads to disseminated intravascular coagulation. ...This review will focus on the rol …
Purpura Fulminans: Mechanism and Management of Dysregulated Hemostasis.
Colling ME, Bendapudi PK. Colling ME, et al. Transfus Med Rev. 2018 Apr;32(2):69-76. doi: 10.1016/j.tmrv.2017.10.001. Epub 2017 Oct 16. Transfus Med Rev. 2018. PMID: 29157918 Review.
PF is associated with an extremely high mortality rate, and patients often die of overwhelming multisystemic thrombosis rather than septic shock. Survivors typically experience amputation of involved extremities and significant scarring in affected areas. ...
PF is associated with an extremely high mortality rate, and patients often die of overwhelming multisystemic thrombosis rather than s …
5,287 results