IFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium.
Wingfield JL, Mengoni I, Bomberger H, Jiang YY, Walsh JD, Brown JM, Picariello T, Cochran DA, Zhu B, Pan J, Eggenschwiler J, Gaertig J, Witman GB, Kner P, Lechtreck K.
Wingfield JL, et al.
Elife. 2017 May 31;6:e26609. doi: 10.7554/eLife.26609.
Elife. 2017.
PMID: 28562242
Free PMC article.
FRAP analysis indicated that IFT proteins and motors of a given train are sequentially recruited to the basal bodies. IFT dynein and tubulin cargoes are loaded briefly before the trains depart. ...
FRAP analysis indicated that IFT proteins and motors of a given train are sequentially recruited to the basal bodies. IFT dynein and …