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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
1992 5
1994 7
1995 12
1996 16
1997 39
1998 41
1999 31
2000 35
2001 15
2002 22
2003 16
2004 12
2005 17
2006 14
2007 14
2008 19
2009 18
2010 37
2011 30
2012 20
2013 22
2014 14
2015 13
2016 12
2017 9
2018 8
2019 8
2020 9
2021 5
2022 7
2023 10
2024 2

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502 results

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Page 1
Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta-analysis.
Huhn M, Nikolakopoulou A, Schneider-Thoma J, Krause M, Samara M, Peter N, Arndt T, Bäckers L, Rothe P, Cipriani A, Davis J, Salanti G, Leucht S. Huhn M, et al. Lancet. 2019 Sep 14;394(10202):939-951. doi: 10.1016/S0140-6736(19)31135-3. Epub 2019 Jul 11. Lancet. 2019. PMID: 31303314 Free PMC article.
Mean differences compared to placebo for weight gain (28 317 participants) ranged from -0.16 kg (-0.73 to 0.40; ziprasidone) to 3.21 kg (2.10 to 4.31; zotepine), for prolactin elevation (21 569 participants) from -77.05 ng/mL (-120.23 to -33.54; clozapine) to 48.51 ng/mL (43.52 t …
Mean differences compared to placebo for weight gain (28 317 participants) ranged from -0.16 kg (-0.73 to 0.40; ziprasidone) to 3.21 kg (2.1 …
Antipsychotic medication and seizures: a review.
Hedges D, Jeppson K, Whitehead P. Hedges D, et al. Drugs Today (Barc). 2003 Jul;39(7):551-7. doi: 10.1358/dot.2003.39.7.799445. Drugs Today (Barc). 2003. PMID: 12973403 Review.
Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis.
Leucht S, Cipriani A, Spineli L, Mavridis D, Orey D, Richter F, Samara M, Barbui C, Engel RR, Geddes JR, Kissling W, Stapf MP, Lässig B, Salanti G, Davis JM. Leucht S, et al. Lancet. 2013 Sep 14;382(9896):951-62. doi: 10.1016/S0140-6736(13)60733-3. Epub 2013 Jun 27. Lancet. 2013. PMID: 23810019 Review.
The standardised mean differences with 95% credible intervals were: clozapine 0.88, 0.73-1.03; amisulpride 0.66, 0.53-0.78; olanzapine 0.59, 0.53-0.65; risperidone 0.56, 0.50-0.63; paliperidone 0.50, 0.39-0.60; zotepine 0.49, 0.31-0.66; haloperidol 0.45, 0.39-0.51; quetiapine 0.4 …
The standardised mean differences with 95% credible intervals were: clozapine 0.88, 0.73-1.03; amisulpride 0.66, 0.53-0.78; olanzapine 0.59, …
Clinical Pharmacokinetics of Atypical Antipsychotics: An Update.
Mauri MC, Paletta S, Di Pace C, Reggiori A, Cirnigliaro G, Valli I, Altamura AC. Mauri MC, et al. Clin Pharmacokinet. 2018 Dec;57(12):1493-1528. doi: 10.1007/s40262-018-0664-3. Clin Pharmacokinet. 2018. PMID: 29915922 Review.
This review concentrates on the clinical pharmacokinetic data related to clozapine, risperidone, paliperidone, olanzapine, quetiapine, amisulpride, ziprasidone, aripiprazole, sertindole, asenapine, iloperidone, lurasidone, brexpiprazole and cariprazine and briefly consider …
This review concentrates on the clinical pharmacokinetic data related to clozapine, risperidone, paliperidone, olanzapine, quetiapine, amisu …
Dose-Response Meta-Analysis of Antipsychotic Drugs for Acute Schizophrenia.
Leucht S, Crippa A, Siafis S, Patel MX, Orsini N, Davis JM. Leucht S, et al. Am J Psychiatry. 2020 Apr 1;177(4):342-353. doi: 10.1176/appi.ajp.2019.19010034. Epub 2019 Dec 16. Am J Psychiatry. 2020. PMID: 31838873
The 95% effective doses and the doses equivalent to 1 mg of oral risperidone, respectively, were as follows: amisulpride for patients with positive symptoms, 537 mg/day and 85.8 mg; aripiprazole, 11.5 mg/day and 1.8 mg; aripiprazole LAI (lauroxil), 463 mg every 4 weeks and 264 mg …
The 95% effective doses and the doses equivalent to 1 mg of oral risperidone, respectively, were as follows: amisulpride for patients with p …
Serotonin control of sleep-wake behavior.
Monti JM. Monti JM. Sleep Med Rev. 2011 Aug;15(4):269-81. doi: 10.1016/j.smrv.2010.11.003. Epub 2011 Apr 2. Sleep Med Rev. 2011. PMID: 21459634 Review.
Of note, systemic administration of the 5-HT(2A/2C) receptor antagonists ritanserin, ketanserin, ICI-170,809 or sertindole at the beginning of the light period has been shown to induce a significant increase of SWS and a reduction of REMS in the rat. ...
Of note, systemic administration of the 5-HT(2A/2C) receptor antagonists ritanserin, ketanserin, ICI-170,809 or sertindole at the beg …
Drug-induced QT Interval Prolongation in the Intensive Care Unit.
Etchegoyen CV, Keller GA, Mrad S, Cheng S, Di Girolamo G. Etchegoyen CV, et al. Curr Clin Pharmacol. 2017;12(4):210-222. doi: 10.2174/1574884713666180223123947. Curr Clin Pharmacol. 2017. PMID: 29473523 Review.
Other noncardiovascular drugs that are widely used in the Intensive Care Unit (ICU), such as ondansetron, macrolide and fluoroquinolone antibiotics, typical and atypical antipsychotics agents such as haloperidol, thioridazine, and sertindole are also frequently associated …
Other noncardiovascular drugs that are widely used in the Intensive Care Unit (ICU), such as ondansetron, macrolide and fluoroquinolone anti …
Antipsychotics and risk of QT prolongation: a pharmacovigilance study.
Bordet C, Garcia P, Salvo F, Touafchia A, Galinier M, Sommet A, Montastruc F. Bordet C, et al. Psychopharmacology (Berl). 2023 Jan;240(1):199-202. doi: 10.1007/s00213-022-06293-4. Epub 2022 Dec 14. Psychopharmacology (Berl). 2023. PMID: 36515735
RATIONALE: While meta-analyses of clinical trials found that lurasidone and partial dopamine agonists (brexpiprazole and aripiprazole) were the antipsychotics less likely to cause QTc prolongation, and sertindole, amisulpride, and ziprasidone were the most frequently assoc …
RATIONALE: While meta-analyses of clinical trials found that lurasidone and partial dopamine agonists (brexpiprazole and aripiprazole) were …
Antipsychotic-induced akathisia in adults with acute schizophrenia: A systematic review and dose-response meta-analysis.
Wu H, Siafis S, Wang D, Burschinski A, Schneider-Thoma J, Priller J, Davis JM, Leucht S. Wu H, et al. Eur Neuropsychopharmacol. 2023 Jul;72:40-49. doi: 10.1016/j.euroneuro.2023.03.015. Epub 2023 Apr 17. Eur Neuropsychopharmacol. 2023. PMID: 37075639
In patients with acute exacerbations of chronic schizophrenia, from moderate to high certainty of evidence, our analysis showed that sertindole and quetiapine carried negligible risks for akathisia across examined doses (flat curves), while most of the other antipsychotics …
In patients with acute exacerbations of chronic schizophrenia, from moderate to high certainty of evidence, our analysis showed that sert …
Schizophrenia.
Barry SJ, Gaughan TM, Hunter R. Barry SJ, et al. BMJ Clin Evid. 2012 Jun 28;2012:1007. BMJ Clin Evid. 2012. PMID: 23870705 Free PMC article. Review.
CONCLUSIONS: In this systematic review, we present information relating to the effectiveness and safety of the following interventions: amisulpride, chlorpromazine, clozapine, depot haloperidol decanoate, haloperidol, olanzapine, pimozide, quetiapine, risperidone, sulpiride, zipr …
CONCLUSIONS: In this systematic review, we present information relating to the effectiveness and safety of the following interventions: amis …
502 results