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1979 1
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1998 3
1999 1
2000 2
2001 3
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Showing results for spiro diuretics
Your search for spiron-diuretics retrieved no results
[Aquaretic agents].
Jiménez W. Jiménez W. Nefrologia. 2002;22 Suppl 5:52-5. Nefrologia. 2002. PMID: 12107918 Free article. Review. Spanish. No abstract available.
3,3-Disubstituted 3,4-Dihydro-1,2,4-benzotriazines: Chemistry, Biological Activity, and Affinity to Sigma Receptors.
Sparatore F, Sparatore A. Sparatore F, et al. Molecules. 2023 Dec 25;29(1):132. doi: 10.3390/molecules29010132. Molecules. 2023. PMID: 38202715 Free PMC article. Review.
Many years later, the structure of this compound, namely, cyclohexane-3-spiro-3,4-dihydro-1,2,4-benzotriazine, was demonstrated. From that time, the reduction of 2-nitrophenylhydrazones of different kinds of ketones, followed by air oxidation of the initially formed amino …
Many years later, the structure of this compound, namely, cyclohexane-3-spiro-3,4-dihydro-1,2,4-benzotriazine, was demonstrated. From …
Diuretics prevent Rho-kinase activation and expression of profibrotic/oxidative genes in the hypertensive aortic wall.
Araos P, Mondaca D, Jalil JE, Yañez C, Novoa U, Mora I, Ocaranza MP. Araos P, et al. Ther Adv Cardiovasc Dis. 2016 Dec;10(6):338-347. doi: 10.1177/1753944716666208. Epub 2016 Sep 1. Ther Adv Cardiovasc Dis. 2016. PMID: 27587602 Free PMC article.
BACKGROUND: Diuretics are current antihypertensive drugs since they reduce blood pressure and cardiovascular risk. ...This pathway has also proremodeling vascular effects. There are few data on the role of diuretics on both vascular ROCK activation and on proremodel …
BACKGROUND: Diuretics are current antihypertensive drugs since they reduce blood pressure and cardiovascular risk. ...This pathway ha …
Pharmacology of vasopressin antagonists.
Costello-Boerrigter LC, Boerrigter G, Burnett JC Jr. Costello-Boerrigter LC, et al. Heart Fail Rev. 2009 Jun;14(2):75-82. doi: 10.1007/s10741-008-9108-8. Epub 2008 Sep 3. Heart Fail Rev. 2009. PMID: 18766438 Review.
Congestive heart failure (CHF) is characterized by fluid and water retention, which frequently is a therapeutic challenge. Most conventional diuretics act primarily as saluretics, i.e. they inhibit renal tubular electrolyte reabsorption, which due to osmotic pressure promo …
Congestive heart failure (CHF) is characterized by fluid and water retention, which frequently is a therapeutic challenge. Most conventional …
Anti-proliferative, Cytotoxic and NF-qB Inhibitory Properties of Spiro(Lactone-Cyclohexanone) Compounds in Human Leukemia.
Bouhenna MM, Orlikova B, Talhi O, Schram B, Pinto DCGA, Taibi N, Bachari K, Diederich M, Silva AMS, Mameri N. Bouhenna MM, et al. Anticancer Res. 2017 Sep;37(9):5225-5233. doi: 10.21873/anticanres.11946. Anticancer Res. 2017. PMID: 28870958
In this study, we evaluated the cytotoxic and NF-qB inhibition potential of new spiro(lactone-cyclohexanone) compounds in two different human leukemia cell lines (U937 and K562). ...RESULTS: Both spiro(coumarin-cyclohexanone) 4 and spiro(6- methyllactone-cycl …
In this study, we evaluated the cytotoxic and NF-qB inhibition potential of new spiro(lactone-cyclohexanone) compounds in two differe …
Nalfurafine, a G-Protein-Biased KOR (Kappa Opioid Receptor) Agonist, Enhances the Diuretic Response and Limits Electrolyte Losses to Standard-of-Care Diuretics.
Meariman JK, Sutphen JC, Gao J, Kapusta DR. Meariman JK, et al. Hypertension. 2022 Feb;79(2):379-390. doi: 10.1161/HYPERTENSIONAHA.121.18503. Epub 2021 Dec 2. Hypertension. 2022. PMID: 34852633 Free PMC article.
We hypothesized that nalfurafine, given its distinct mechanism of vasopressin inhibition, would increase urine output to these diuretics and limit electrolyte loss. Following catheterization, conscious Sprague-Dawley rats received an isotonic saline infusion and were then …
We hypothesized that nalfurafine, given its distinct mechanism of vasopressin inhibition, would increase urine output to these diuretics …
A systematic review of known interventions for the treatment of chronic nonhypovolaemic hypotonic hyponatraemia and a meta-analysis of the vaptans.
Bhandari S, Peri A, Cranston I, McCool R, Shaw A, Glanville J, Petrakova L, O'Reilly K. Bhandari S, et al. Clin Endocrinol (Oxf). 2017 Jun;86(6):761-771. doi: 10.1111/cen.13315. Epub 2017 Mar 27. Clin Endocrinol (Oxf). 2017. PMID: 28214374 Review.
No RCT evidence of treatments other than the vaptans for hyponatraemia such as oral urea, salt tablets, mannitol, loop diuretics demeclocycline or lithium was identified. Vaptans demonstrated superiority over placebo for outcomes relating to serum sodium correction. ...
No RCT evidence of treatments other than the vaptans for hyponatraemia such as oral urea, salt tablets, mannitol, loop diuretics deme …
113 results