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995 results

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Page 1
Synechococcus elongatus PCC7942 secretes extracellular vesicles to accelerate cutaneous wound healing by promoting angiogenesis.
Yin H, Chen CY, Liu YW, Tan YJ, Deng ZL, Yang F, Huang FY, Wen C, Rao SS, Luo MJ, Hu XK, Liu ZZ, Wang ZX, Cao J, Liu HM, Liu JH, Yue T, Tang SY, Xie H. Yin H, et al. Theranostics. 2019 Apr 13;9(9):2678-2693. doi: 10.7150/thno.31884. eCollection 2019. Theranostics. 2019. PMID: 31131061 Free PMC article.
GW4869 was used to interfere with the secretion of EVs by the cyanobacterium and the abilities of the GW4869-pretreated and untreated Synechococcus elongatus PCC 7942 to regulate endothelial angiogenesis were compared. ...The expression of interleukin 6 (IL-6), whic …
GW4869 was used to interfere with the secretion of EVs by the cyanobacterium and the abilities of the GW4869-pretreated and untreated Syn …
Synechococcus elongatus PCC 7942 as a Platform for Bioproduction of Omega-3 Fatty Acids.
Santos-Merino M, Gutiérrez-Lanza R, Nogales J, García JL, de la Cruz F. Santos-Merino M, et al. Life (Basel). 2022 May 29;12(6):810. doi: 10.3390/life12060810. Life (Basel). 2022. PMID: 35743841 Free PMC article.
To gain insight into the cyanobacterial fatty acid biosynthesis pathways, we analyzed two enzymes involved in the elongation cycle, FabG and FabZ, in Synechococcus elongatus PCC 7942. Overexpression of these two enzymes led to an increase in C18 fatty acids, key int …
To gain insight into the cyanobacterial fatty acid biosynthesis pathways, we analyzed two enzymes involved in the elongation cycle, FabG and …
Base editing for reprogramming cyanobacterium Synechococcus elongatus.
Wang SY, Li X, Wang SG, Xia PF. Wang SY, et al. Metab Eng. 2023 Jan;75:91-99. doi: 10.1016/j.ymben.2022.11.005. Epub 2022 Nov 18. Metab Eng. 2023. PMID: 36403709
We achieved precise and efficient genome editing at a single-nucleotide resolution and demonstrated multiplex base editing in the model cyanobacterium Synechococcus elongatus. By using the base-editing tool, we successfully manipulated the glycogen metabolic pathway …
We achieved precise and efficient genome editing at a single-nucleotide resolution and demonstrated multiplex base editing in the model cyan …
Metabolic engineering of Synechococcus elongatus for photoautotrophic production of mannitol.
Pritam P, Sarnaik AP, Wangikar PP. Pritam P, et al. Biotechnol Bioeng. 2023 Aug;120(8):2363-2370. doi: 10.1002/bit.28479. Epub 2023 Jun 30. Biotechnol Bioeng. 2023. PMID: 37387320
Considering the sustainability prospects, the current work encompasses metabolic engineering of a widely used cyanobacterial strain, Synechococcus elongatus PCC 7942, and two newly isolated fast-growing cyanobacterial strains; S. elongatus PCC 11801 and S. elongatus …
Considering the sustainability prospects, the current work encompasses metabolic engineering of a widely used cyanobacterial strain, Syne …
Temperature-induced zeaxanthin overproduction in Synechococcus elongatus PCC 7942.
Casazza AP, Lombardi A, Menin B, Santabarbara S. Casazza AP, et al. Photochem Photobiol Sci. 2023 Apr;22(4):783-794. doi: 10.1007/s43630-022-00352-7. Epub 2022 Dec 19. Photochem Photobiol Sci. 2023. PMID: 36536270
SD212, coding for a 3,3' beta-car hydroxylase, was expressed in Synechococcus elongatus PCC 7942 under the control of a temperature-inducible promoter in an attempt to engineer the carotenoid metabolic pathway, to increase the content of zeaxanthin and its further h …
SD212, coding for a 3,3' beta-car hydroxylase, was expressed in Synechococcus elongatus PCC 7942 under the control of a temper …
Comparative Genomics of Synechococcus elongatus Explains the Phenotypic Diversity of the Strains.
Adomako M, Ernst D, Simkovsky R, Chao YY, Wang J, Fang M, Bouchier C, Lopez-Igual R, Mazel D, Gugger M, Golden SS. Adomako M, et al. mBio. 2022 Jun 28;13(3):e0086222. doi: 10.1128/mbio.00862-22. Epub 2022 Apr 27. mBio. 2022. PMID: 35475644 Free PMC article.
Strains of the freshwater cyanobacterium Synechococcus elongatus were first isolated approximately 60 years ago, and PCC 7942 is well established as a model for photosynthesis, circadian biology, and biotechnology research. ...One SNP in the circadian response regul …
Strains of the freshwater cyanobacterium Synechococcus elongatus were first isolated approximately 60 years ago, and PCC 7942 …
Transcriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth.
Tan LR, Cao YQ, Li JW, Xia PF, Wang SG. Tan LR, et al. Microb Cell Fact. 2022 Mar 5;21(1):31. doi: 10.1186/s12934-022-01760-1. Microb Cell Fact. 2022. PMID: 35248031 Free PMC article.
This work aimed to fill the gap at omics level. RESULTS: We first constructed two engineered Synechococcus elongatus YQ2-gal and YQ3-xyl capable of utilizing glucose and xylose, respectively. ...
This work aimed to fill the gap at omics level. RESULTS: We first constructed two engineered Synechococcus elongatus YQ2-gal a …
Metabolic engineering of Synechococcus elongatus 7942 for enhanced sucrose biosynthesis.
Wang B, Zuniga C, Guarnieri MT, Zengler K, Betenbaugh M, Young JD. Wang B, et al. Metab Eng. 2023 Nov;80:12-24. doi: 10.1016/j.ymben.2023.09.002. Epub 2023 Sep 9. Metab Eng. 2023. PMID: 37678664
Here, we investigated global metabolic flux alterations in a sucrose-secreting (cscB-overexpressing) strain relative to its wild-type Synechococcus elongatus 7942 parental strain. We used targeted metabolomics, (13)C metabolic flux analysis (MFA), and genome-scale m …
Here, we investigated global metabolic flux alterations in a sucrose-secreting (cscB-overexpressing) strain relative to its wild-type Syn …
995 results