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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
1965 6
1969 1
1973 1
1974 6
1975 50
1976 65
1977 64
1978 80
1979 63
1980 70
1981 71
1982 92
1983 82
1984 73
1985 93
1986 112
1987 132
1988 137
1989 177
1990 231
1991 269
1992 370
1993 583
1994 778
1995 1102
1996 1576
1997 1794
1998 1999
1999 2336
2000 2652
2001 2748
2002 2599
2003 2846
2004 3133
2005 3199
2006 3078
2007 2952
2008 2919
2009 3118
2010 3233
2011 3763
2012 3947
2013 3761
2014 3757
2015 3740
2016 3663
2017 3397
2018 3144
2019 3227
2020 3170
2021 2791
2022 1945
2023 1680
2024 672

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79,828 results

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Page 1
Rediscovering tandem repeat variation in schizophrenia: challenges and opportunities.
Birnbaum R. Birnbaum R. Transl Psychiatry. 2023 Dec 20;13(1):402. doi: 10.1038/s41398-023-02689-8. Transl Psychiatry. 2023. PMID: 38123544 Free PMC article. Review.
The high mutation rate of TRs, which can be orders of magnitude higher than single-nucleotide polymorphisms and indels, indicates that they are likely to make significant contributions to phenotypic variation, yet their contribution to schizophrenia has been largely ignored by re …
The high mutation rate of TRs, which can be orders of magnitude higher than single-nucleotide polymorphisms and indels, indicates that they …
Analysis of Tandem Repeat Protein Folding Using Nearest-Neighbor Models.
Petersen M, Barrick D. Petersen M, et al. Annu Rev Biophys. 2021 May 6;50:245-265. doi: 10.1146/annurev-biophys-102220-083020. Epub 2021 Feb 19. Annu Rev Biophys. 2021. PMID: 33606943 Free PMC article. Review.
Cooperativity is a hallmark of protein folding, but the thermodynamic origins of cooperativity are difficult to quantify. Tandem repeat proteins provide a unique experimental system to quantify cooperativity due to their internal symmetry and their tolerance of dele …
Cooperativity is a hallmark of protein folding, but the thermodynamic origins of cooperativity are difficult to quantify. Tandem r …
TRiCoLOR: tandem repeat profiling using whole-genome long-read sequencing data.
Bolognini D, Magi A, Benes V, Korbel JO, Rausch T. Bolognini D, et al. Gigascience. 2020 Oct 7;9(10):giaa101. doi: 10.1093/gigascience/giaa101. Gigascience. 2020. PMID: 33034633 Free PMC article.
BACKGROUND: Tandem repeat sequences are widespread in the human genome, and their expansions cause multiple repeat-mediated disorders. ...RESULTS: We developed TRiCoLOR, a freely available tool for tandem repeat profiling using error-pron …
BACKGROUND: Tandem repeat sequences are widespread in the human genome, and their expansions cause multiple repeat …
Conversion of DNA Sequences: From a Transposable Element to a Tandem Repeat or to a Gene.
Paço A, Freitas R, Vieira-da-Silva A. Paço A, et al. Genes (Basel). 2019 Dec 5;10(12):1014. doi: 10.3390/genes10121014. Genes (Basel). 2019. PMID: 31817529 Free PMC article. Review.
Eukaryotic genomes are rich in repetitive DNA sequences grouped in two classes regarding their genomic organization: tandem repeats and dispersed repeats. In tandem repeats, copies of a short DNA sequence are positioned one after another within the genome, wh …
Eukaryotic genomes are rich in repetitive DNA sequences grouped in two classes regarding their genomic organization: tandem re …
Analysis of Tandem Repeat Expansions Using Long DNA Reads.
Mitsuhashi S, Frith MC. Mitsuhashi S, et al. Methods Mol Biol. 2023;2632:147-159. doi: 10.1007/978-1-0716-2996-3_11. Methods Mol Biol. 2023. PMID: 36781727
Long read sequencers enable us to directly analyze repeat length and sequence content by covering whole repeats; they are therefore considered suitable for the analysis of long tandem repeats. Here, we describe an expanded repeat analysis using target sequenc …
Long read sequencers enable us to directly analyze repeat length and sequence content by covering whole repeats; they are therefore c …
Advancing genomic technologies and clinical awareness accelerates discovery of disease-associated tandem repeat sequences.
Gall-Duncan T, Sato N, Yuen RKC, Pearson CE. Gall-Duncan T, et al. Genome Res. 2022 Jan;32(1):1-27. doi: 10.1101/gr.269530.120. Epub 2021 Dec 29. Genome Res. 2022. PMID: 34965938 Free PMC article. Review.
Discovery of disease-causing repeat expansion loci accelerated through technological advances in DNA sequencing and computational analyses. ...Repeat motif size can be a single nucleotide to kilobases/unit. At a given locus, repeat motif sequence purity can v …
Discovery of disease-causing repeat expansion loci accelerated through technological advances in DNA sequencing and computational ana …
Human tandem repeat sequences in forensic DNA typing.
Tamaki K, Jeffreys AJ. Tamaki K, et al. Leg Med (Tokyo). 2005 Jul;7(4):244-50. doi: 10.1016/j.legalmed.2005.02.002. Leg Med (Tokyo). 2005. PMID: 15939656 Free article. Review.
It has been 20 years since the first development of DNA fingerprinting and the start of forensic DNA typing. Ever since, human tandem repeat DNA sequences have been the main targets for forensic DNA analysis. These repeat sequences are classifie …
It has been 20 years since the first development of DNA fingerprinting and the start of forensic DNA typing. Ever since, human tandem …
Tandem repeat peptide strategy for the design of neurotrophic factor mimetics.
Molina-Holgado F, Doherty P, Williams G. Molina-Holgado F, et al. CNS Neurol Disord Drug Targets. 2008 Feb;7(1):110-9. doi: 10.2174/187152708783885200. CNS Neurol Disord Drug Targets. 2008. PMID: 18289037 Review.
The review gives a brief survey of the various strategies to design mimetics that have been reported in the literature with special emphasis on the tandem repeat peptide agonist approach for BDNF/NT-4/5 and N-cadherin mimetics....
The review gives a brief survey of the various strategies to design mimetics that have been reported in the literature with special emphasis …
Expanding the repertoire of human tandem repeat RNA-binding proteins.
Ormazábal A, Carletti MS, Saldaño TE, Gonzalez Buitron M, Marchetti J, Palopoli N, Bateman A. Ormazábal A, et al. PLoS One. 2023 Sep 20;18(9):e0290890. doi: 10.1371/journal.pone.0290890. eCollection 2023. PLoS One. 2023. PMID: 37729217 Free PMC article.
Although the interactions between repeat proteins and DNA are already widely explored, studies characterising tandem repeat RNA-binding proteins are lacking. ...Our results showed that the combination of sequence and structural methods finds significantly mor …
Although the interactions between repeat proteins and DNA are already widely explored, studies characterising tandem repeat …
Mechanisms of tandem repeat instability in bacteria.
Bichara M, Wagner J, Lambert IB. Bichara M, et al. Mutat Res. 2006 Jun 25;598(1-2):144-63. doi: 10.1016/j.mrfmmm.2006.01.020. Epub 2006 Mar 7. Mutat Res. 2006. PMID: 16519906 Review.
Hypermutable tandem repeat sequences (TRSs) are present in the genomes of both prokaryotic and eukaryotic organisms. ...Both the frequency of tandem repeat instability (TRI), and the types of mutational events that arise, are markedly influenced …
Hypermutable tandem repeat sequences (TRSs) are present in the genomes of both prokaryotic and eukaryotic organisms. .. …
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