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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 8
1946 30
1947 31
1948 28
1949 18
1950 25
1951 61
1952 72
1953 76
1954 83
1955 87
1956 94
1957 100
1958 98
1959 115
1960 120
1961 146
1962 98
1963 107
1964 254
1965 248
1966 241
1967 286
1968 346
1969 422
1970 412
1971 442
1972 560
1973 554
1974 672
1975 602
1976 673
1977 689
1978 659
1979 678
1980 871
1981 913
1982 1123
1983 1202
1984 1457
1985 1986
1986 2201
1987 2360
1988 2538
1989 2802
1990 3277
1991 3515
1992 3691
1993 3914
1994 4094
1995 4146
1996 4106
1997 4215
1998 4228
1999 4197
2000 4605
2001 4762
2002 4587
2003 4719
2004 4880
2005 5297
2006 5458
2007 5705
2008 5861
2009 6064
2010 6377
2011 7151
2012 7810
2013 7806
2014 7985
2015 8105
2016 7794
2017 7745
2018 7936
2019 8447
2020 8076
2021 7087
2022 6239
2023 4574
2024 2173

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204,395 results

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Page 1
Engineering fungal terpene biosynthesis.
Yin Z, Dickschat JS. Yin Z, et al. Nat Prod Rep. 2023 Jan 25;40(1):28-45. doi: 10.1039/d2np00020b. Nat Prod Rep. 2023. PMID: 35604115 Review.
Terpene biosynthesis: modularity rules.
Oldfield E, Lin FY. Oldfield E, et al. Angew Chem Int Ed Engl. 2012 Jan 27;51(5):1124-37. doi: 10.1002/anie.201103110. Epub 2011 Nov 21. Angew Chem Int Ed Engl. 2012. PMID: 22105807 Free PMC article. Review.
Terpenes are the largest class of small-molecule natural products on earth, and the most abundant by mass. Here, we summarize recent developments in elucidating the structure and function of the proteins involved in their biosynthesis. There are six main building bl …
Terpenes are the largest class of small-molecule natural products on earth, and the most abundant by mass. Here, we summarize recent …
Biosynthesis of terpene compounds using the non-model yeast Yarrowia lipolytica: grand challenges and a few perspectives.
Worland AM, Czajka JJ, Li Y, Wang Y, Tang YJ, Su WW. Worland AM, et al. Curr Opin Biotechnol. 2020 Aug;64:134-140. doi: 10.1016/j.copbio.2020.02.020. Epub 2020 Apr 13. Curr Opin Biotechnol. 2020. PMID: 32299032 Free PMC article. Review.
Yarrowia lipolytica has emerged as an important non-model host for terpene production. However, three main challenges remain in industrial production using this yeast. ...Further developments that address these challenges are needed to advance the Yarrowia lipolytica platf …
Yarrowia lipolytica has emerged as an important non-model host for terpene production. However, three main challenges remain in indus …
The Cannabis Terpenes.
Sommano SR, Chittasupho C, Ruksiriwanich W, Jantrawut P. Sommano SR, et al. Molecules. 2020 Dec 8;25(24):5792. doi: 10.3390/molecules25245792. Molecules. 2020. PMID: 33302574 Free PMC article. Review.
Terpenes are the primary constituents of essential oils and are responsible for the aroma characteristics of cannabis. ...They also enhance many therapeutic benefits, especially as aromatherapy. To shed light on the importance of terpenes in the cannabis industry, t …
Terpenes are the primary constituents of essential oils and are responsible for the aroma characteristics of cannabis. ...They also e …
Medically Useful Plant Terpenoids: Biosynthesis, Occurrence, and Mechanism of Action.
Bergman ME, Davis B, Phillips MA. Bergman ME, et al. Molecules. 2019 Nov 1;24(21):3961. doi: 10.3390/molecules24213961. Molecules. 2019. PMID: 31683764 Free PMC article. Review.
Here we review some of the most effective and promising plant terpenoids that are currently used in medicine and medical research and provide updates on their biosynthesis, natural occurrence, and mechanism of action in the body. ...
Here we review some of the most effective and promising plant terpenoids that are currently used in medicine and medical research and provid …
ATP Drives Efficient Terpene Biosynthesis in Marine Thraustochytrids.
Zhang A, Mernitz K, Wu C, Xiong W, He Y, Wang G, Wang X. Zhang A, et al. mBio. 2021 Jun 29;12(3):e0088121. doi: 10.1128/mBio.00881-21. Epub 2021 Jun 29. mBio. 2021. PMID: 34182781 Free PMC article.
Understanding carbon flux controlling mechanisms in a tangled metabolic network is an essential question of cell metabolism. Secondary metabolism, such as terpene biosynthesis, has evolved with low carbon flux due to inherent pathway constraints. ...Me …
Understanding carbon flux controlling mechanisms in a tangled metabolic network is an essential question of cell metabolism. Secondar …
Terpene synthases and pathways in animals: enzymology and structural evolution in the biosynthesis of volatile infochemicals.
Tholl D, Rebholz Z, Morozov AV, O'Maille PE. Tholl D, et al. Nat Prod Rep. 2023 Apr 26;40(4):766-793. doi: 10.1039/d2np00076h. Nat Prod Rep. 2023. PMID: 36880348 Review.
In addition, terpene synthase (TPS) enzymes have been discovered that are evolutionary unrelated to canonical plant and microbial TPSs and instead resemble precursor enzymes called isoprenyl diphosphate synthases (IDSs) in central terpene metabolism. ...Toget …
In addition, terpene synthase (TPS) enzymes have been discovered that are evolutionary unrelated to canonical plant and microbial TPS …
Terpene Synthases in the Biosynthesis of Drimane-Type Sesquiterpenes across Diverse Organisms.
Chen TH, Lin HC. Chen TH, et al. Chembiochem. 2023 Nov 16;24(22):e202300518. doi: 10.1002/cbic.202300518. Epub 2023 Sep 13. Chembiochem. 2023. PMID: 37605310
We summarize and discuss their key features, including the chemical mechanisms, catalytic motifs and functional domains employed by these terpene synthases to generate DTS scaffolds....
We summarize and discuss their key features, including the chemical mechanisms, catalytic motifs and functional domains employed by these …
The carbocation continuum in terpene biosynthesis--where are the secondary cations?
Tantillo DJ. Tantillo DJ. Chem Soc Rev. 2010 Aug;39(8):2847-54. doi: 10.1039/b917107j. Epub 2010 May 4. Chem Soc Rev. 2010. PMID: 20442917 Review.
In this tutorial review, structures encountered in carbocation cascade polycyclization reactions leading to terpene natural products are surveyed. The nature of delocalization in these carbocations is discussed in detail. ...
In this tutorial review, structures encountered in carbocation cascade polycyclization reactions leading to terpene natural products …
Bacterial terpene cyclases.
Dickschat JS. Dickschat JS. Nat Prod Rep. 2016 Jan;33(1):87-110. doi: 10.1039/c5np00102a. Nat Prod Rep. 2016. PMID: 26563452 Review.
This review summarises the accumulated knowledge about characterised bacterial terpene cyclases. The structures of identified products and of crystallised enzymes are included, and the obtained insights into enzyme mechanisms are discussed. ...
This review summarises the accumulated knowledge about characterised bacterial terpene cyclases. The structures of identified product …
204,395 results
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