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Year Number of Results
1987 1
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2003 28
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2005 37
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536 results

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Page 1
Usage of Synthetic Peptides in Cosmetics for Sensitive Skin.
Resende DISP, Ferreira MS, Sousa-Lobo JM, Sousa E, Almeida IF. Resende DISP, et al. Pharmaceuticals (Basel). 2021 Jul 21;14(8):702. doi: 10.3390/ph14080702. Pharmaceuticals (Basel). 2021. PMID: 34451799 Free PMC article. Review.
Peptides were found in 17% of the products analyzed, namely: acetyl dipeptide-1 cetyl ester, palmitoyl tripeptide-8, acetyl tetrapeptide-15, palmitoyl tripeptide-5, acetyl hexapeptide-49, palmitoyl tetrapeptide-7 and palmitoyl oligopeptide. ...
Peptides were found in 17% of the products analyzed, namely: acetyl dipeptide-1 cetyl ester, palmitoyl tripeptide-8, acetyl tetrapeptide
Pain inhibition by endomorphins.
Przewłocki R, Labuz D, Mika J, Przewłocka B, Tomboly C, Toth G. Przewłocki R, et al. Ann N Y Acad Sci. 1999;897:154-64. doi: 10.1111/j.1749-6632.1999.tb07887.x. Ann N Y Acad Sci. 1999. PMID: 10676444 Review.
Spinal analgesic effects of endomorphin-1 and endomorphin-2 were studied during acute, inflammatory, and neuropathic pain in rats chronically implanted with intrathecal cannulas. Endomorphin-1 and endomorphin-2 (2.5-10 micrograms i.t.), as well as thei …
Spinal analgesic effects of endomorphin-1 and endomorphin-2 were studied during acute, inflammatory, and neuropathic pain in r …
The sigma-1 receptor curtails endogenous opioid analgesia during sensitization of TRPV1 nociceptors.
Ruiz-Cantero MC, Cortés-Montero E, Jain A, Montilla-García Á, Bravo-Caparrós I, Shim J, Sánchez-Blázquez P, Woolf CJ, Baeyens JM, Cobos EJ. Ruiz-Cantero MC, et al. Br J Pharmacol. 2023 Apr;180(8):1148-1167. doi: 10.1111/bph.16003. Epub 2022 Dec 29. Br J Pharmacol. 2023. PMID: 36478100 Free article.
We used immunohistochemistry to determine the presence of endomorphin-2, an endogenous mu receptor agonist, on dorsal root ganglion (DRG) neurons. ...KEY RESULTS: Sigma1 antagonists reversed PGE2- and NGF-induced hyperalgesia but not GDNF-induced hyperalgesia. En
We used immunohistochemistry to determine the presence of endomorphin-2, an endogenous mu receptor agonist, on dorsal root gan …
Recent advances in endomorphin engineering.
Keresztes A, Borics A, Tóth G. Keresztes A, et al. ChemMedChem. 2010 Aug 2;5(8):1176-96. doi: 10.1002/cmdc.201000077. ChemMedChem. 2010. PMID: 20491136 Review.
Harnessing endogenous opioids for pain relief: Fantasy vs reality.
Gintzler AR, Liu NJ. Gintzler AR, et al. J Opioid Manag. 2019 Jan/Feb;16(1):67-72. doi: 10.5055/jom.2020.0552. J Opioid Manag. 2019. PMID: 32091619 Free PMC article. Review.
Based on insights gleaned from mechanisms underlying the ebb and flow of analgesic responsiveness to the spinal application of endomorphin 2, multiple signaling proteins were identified that activate endogenous spinal opioid analgesia. ...
Based on insights gleaned from mechanisms underlying the ebb and flow of analgesic responsiveness to the spinal application of endomorphi
Engineering endomorphin drugs: state of the art.
Lazarus LH, Okada Y. Lazarus LH, et al. Expert Opin Ther Pat. 2012 Jan;22(1):1-14. doi: 10.1517/13543776.2012.646261. Epub 2012 Jan 4. Expert Opin Ther Pat. 2012. PMID: 22214283 Free PMC article. Review.
Exploiting endogenous opioids: Lessons learned from endomorphin 2 in the female rat.
Gintzler AR, Liu NJ, Storman EM, Wessendorf MW. Gintzler AR, et al. Peptides. 2019 Feb;112:133-138. doi: 10.1016/j.peptides.2018.12.002. Epub 2018 Dec 14. Peptides. 2019. PMID: 30557590 Free PMC article. Review.
Based on our studies of endogenous mechanism that suppress and facilitate spinal endomorphin 2 antinociception over the rat reproductive cycle, we identified multiple signaling molecules that could serve as targets for activating endogenous opioid analgesia for chro …
Based on our studies of endogenous mechanism that suppress and facilitate spinal endomorphin 2 antinociception over the rat re …
From the Anti-Nociceptive Substance P Metabolite Substance P (1-7) to Small Peptidomimetics.
Hallberg M, Sandstrom A. Hallberg M, et al. Curr Protein Pept Sci. 2018;19(11):1038-1048. doi: 10.2174/1389203719666180508122019. Curr Protein Pept Sci. 2018. PMID: 29745331 Review.
Endomorphin-2 subjected to truncations yielded the potent dipeptide amide Phe-Phe-NH2. ...Although, additional structural modifications are needed to achieve compounds exhibiting high/fair bioavailability after oral administration, the examples presented herein demo
Endomorphin-2 subjected to truncations yielded the potent dipeptide amide Phe-Phe-NH2. ...Although, additional structural modi
536 results