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Page 1
The Significance of Tinospora crispa in Treatment of Diabetes Mellitus.
Thomas A, Rajesh EK, Kumar DS. Thomas A, et al. Phytother Res. 2016 Mar;30(3):357-66. doi: 10.1002/ptr.5559. Epub 2016 Jan 7. Phytother Res. 2016. PMID: 26749336 Review.
Tinospora crispa is a medicinal plant belonging to the botanical family Menispermiaceae. The plant is widely distributed in Southeast Asia and the northeastern region of India. A related species Tinospora cordifolia is used in Ayurveda for treating a large sp …
Tinospora crispa is a medicinal plant belonging to the botanical family Menispermiaceae. The plant is widely distributed in So …
Tinospora crispa (L.) Hook. f. & Thomson: A Review of Its Ethnobotanical, Phytochemical, and Pharmacological Aspects.
Ahmad W, Jantan I, Bukhari SN. Ahmad W, et al. Front Pharmacol. 2016 Mar 21;7:59. doi: 10.3389/fphar.2016.00059. eCollection 2016. Front Pharmacol. 2016. PMID: 27047378 Free PMC article. Review.
Tinospora crispa (L.) Hook. f. & Thomson (Menispermaceae), found in the rainforests or mixed deciduous forests in Asia and Africa, is used in traditional medicines to treat numerous health conditions. ...Further investigations are required to transform the exper …
Tinospora crispa (L.) Hook. f. & Thomson (Menispermaceae), found in the rainforests or mixed deciduous forests in Asia and …
Rearranged clerodane diterpenoid from Tinospora crispa.
Parveen A, Huang Y, Fantoukh O, Alhusban M, Raman V, Wang YH, Wang W, Ali Z, Khan IA. Parveen A, et al. Nat Prod Res. 2021 Feb;35(3):369-376. doi: 10.1080/14786419.2019.1633648. Epub 2019 Jun 27. Nat Prod Res. 2021. PMID: 31242768
A new rearranged clerodane diterpenoid, tinocrispide was isolated from the stems of Tinospora crispa along with thirteen known compounds including eight clerodane diterpenoids. Among the known compounds baenzigeride A, (6S, 9 R)-vomifoliol and steponine are being re …
A new rearranged clerodane diterpenoid, tinocrispide was isolated from the stems of Tinospora crispa along with thirteen known …
An updated and comprehensive review on the ethnomedicinal uses, phytochemistry, pharmacological activity and toxicological profile of Tinospora crispa (L.) Hook. f. & Thomson.
Haque E, Bari MS, Khandokar L, Anjum J, Jantan I, Seidel V, Haque MA. Haque E, et al. Phytochem Rev. 2023;22(1):211-273. doi: 10.1007/s11101-022-09843-y. Epub 2022 Nov 3. Phytochem Rev. 2023. PMID: 36345416 Free PMC article. Review.
Tinospora crispa (L.) Hook. f. & Thomson (Menispermaceae) is a plant indigenous to Africa and South-East Asia. ...The exact identity of the phytoconstituents responsible for the observed biological effects and their mode of action at the molecular level are yet …
Tinospora crispa (L.) Hook. f. & Thomson (Menispermaceae) is a plant indigenous to Africa and South-East Asia. ...The exac …
Literature review of liver injury induced by Tinospora crispa associated with two cases of acute fulminant hepatitis.
Huang WT, Tu CY, Wang FY, Huang ST. Huang WT, et al. Complement Ther Med. 2019 Feb;42:286-291. doi: 10.1016/j.ctim.2018.11.028. Epub 2018 Dec 6. Complement Ther Med. 2019. PMID: 30670256 Review.
However, there are an increasing number of cases revealing that Tinospora crispa (TCP) might have the negative effect of inducing hepatotoxicity. ...Given that the two herbs were misidentified in these two reports, we investigated the frequency of erroneous identifi …
However, there are an increasing number of cases revealing that Tinospora crispa (TCP) might have the negative effect of induc …
One novel alkaloid from the stems of Tinospora crispa.
Huang F, Gongpan P, Ji K, Zhou L, Song Q, Fan Q. Huang F, et al. Nat Prod Res. 2023 Oct 22:1-6. doi: 10.1080/14786419.2023.2272023. Online ahead of print. Nat Prod Res. 2023. PMID: 37865970
The 6-methoxy-cannabisin I (1), a new alkaloid, together with five known compounds oleraisoindole A (2), cannabisin F (3), apigenin (4), syringin (5) and ethyl-syringin (6) were isolated from Tinospora crispa stems. Their structures were identified by the analysis o …
The 6-methoxy-cannabisin I (1), a new alkaloid, together with five known compounds oleraisoindole A (2), cannabisin F (3), apigenin (4), syr …
Probing PXR activation and modulation of CYP3A4 by Tinospora crispa and Tinospora sinensis.
Parveen A, Alhusban M, Fantoukh OI, Ali Z, Chittiboyina AG, Khan IA, Khan SI. Parveen A, et al. J Ethnopharmacol. 2022 Jun 12;291:115159. doi: 10.1016/j.jep.2022.115159. Epub 2022 Mar 1. J Ethnopharmacol. 2022. PMID: 35245632
ETHNOPHARMACOLOGICAL RELEVANCE: The two Tinospora species, T. crispa and T. sinensis, native to Southeast Asia, are integral components of various traditional preparations with structure-function claims to treat various disorders, including diabetes and inflammation …
ETHNOPHARMACOLOGICAL RELEVANCE: The two Tinospora species, T. crispa and T. sinensis, native to Southeast Asia, are integral c …
Magnoflorine from Tinospora crispa upregulates innate and adaptive immune responses in Balb/c mice.
Ahmad W, Jantan I, Haque MA, Arsyad L. Ahmad W, et al. Int Immunopharmacol. 2022 Oct;111:109081. doi: 10.1016/j.intimp.2022.109081. Epub 2022 Jul 27. Int Immunopharmacol. 2022. PMID: 35907339
However, its effects on the immune responses in animal studies have not been reported. In this study, magnoflorine isolated from Tinospora crispa, at doses of 25, 50 and 100 mg/kg was administered to male Balb/c mice daily for 14 days to evaluate its effect on innat …
However, its effects on the immune responses in animal studies have not been reported. In this study, magnoflorine isolated from Tinospor …
Tinopanoids K-T, clerodane diterpenoids with anti-inflammatory activity from Tinospora crispa.
Zhu YL, Deng L, Dai XY, Song JQ, Zhu Y, Liu T, Kong XQ, Zhang LJ, Liao HB. Zhu YL, et al. Bioorg Chem. 2023 Nov;140:106812. doi: 10.1016/j.bioorg.2023.106812. Epub 2023 Aug 27. Bioorg Chem. 2023. PMID: 37651894
A total of 17 structurally diverse clerodane diterpenoids, including ten undescribed clerodane diterpenoids (tinopanoids K-T, 1-10) and seven known compounds (11-17), were isolated from the vines and leaves of Tinospora crispa. Compound 3 has not only bear the domin …
A total of 17 structurally diverse clerodane diterpenoids, including ten undescribed clerodane diterpenoids (tinopanoids K-T, 1-10) and seve …
Diterpenoids and Their Glycosides from the Stems of Tinospora crispa with Beta-Cell Protective Activity.
Lam SH, Liu HK, Chung SY, Chang JL, Hong MX, Kuo SC, Liaw CC. Lam SH, et al. J Nat Prod. 2023 Jun 23;86(6):1437-1448. doi: 10.1021/acs.jnatprod.3c00114. Epub 2023 May 18. J Nat Prod. 2023. PMID: 37200063
Seven previously undescribed diterpenoids, tinocrisposides A-D (1-4) and borapetic acids A (5), B (6), and C (7), together with 16 known compounds, were isolated from the stem of Tinospora crispa (Menispermaceae). The structures of the new isolates were elucidated b …
Seven previously undescribed diterpenoids, tinocrisposides A-D (1-4) and borapetic acids A (5), B (6), and C (7), together with 16 known com …
94 results