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Lack of pharmacokinetic interaction between the oral anti-influenza neuraminidase inhibitor prodrug oseltamivir and antacids.
Snell P, Oo C, Dorr A, Barrett J. Snell P, et al. Br J Clin Pharmacol. 2002 Oct;54(4):372-7. doi: 10.1046/j.1365-2125.2002.01678.x. Br J Clin Pharmacol. 2002. PMID: 12392584 Free PMC article. Clinical Trial.
Each volunteer received in a fasted state, 150 mg oseltamivir alone (Treatment A), 150 mg oseltamivir with a 20 ml Maalox suspension (Treatment B), and 150 mg oseltamivir with four Titralac tablets (Treatment C), with 7-10 days washout in between treatments. ...CONCLUSIONS …
Each volunteer received in a fasted state, 150 mg oseltamivir alone (Treatment A), 150 mg oseltamivir with a 20 ml Maalox suspension (Treatm …
Inhibition of norfloxacin absorption by antacids.
Nix DE, Wilton JH, Ronald B, Distlerath L, Williams VC, Norman A. Nix DE, et al. Antimicrob Agents Chemother. 1990 Mar;34(3):432-5. doi: 10.1128/AAC.34.3.432. Antimicrob Agents Chemother. 1990. PMID: 2334155 Free PMC article. Clinical Trial.
Treatments included 400 mg of norfloxacin alone, 400 mg of norfloxacin 5 min after aluminum-magnesium hydroxide (Maalox), Maalox 2 h after 400 mg of norfloxacin, and 400 mg of norfloxacin 5 min after calcium carbonate (Titralac). Blood and urine samples were collected at p …
Treatments included 400 mg of norfloxacin alone, 400 mg of norfloxacin 5 min after aluminum-magnesium hydroxide (Maalox), Maalox 2 h after 4 …
Calcium carbonate 1250 mg/1260 mg: an effective phosphate binder.
Taylor JE, Henderson IS, Stewart WK, Mactier RA. Taylor JE, et al. Scott Med J. 1990 Apr;35(2):45-7. doi: 10.1177/003693309003500205. Scott Med J. 1990. PMID: 2374904
In a group of seven patients, we have compared Titralac with two alternative preparations containing calcium carbonate 1250 mg (Calcium-500 Macarthy's Medical Ltd) and calcium carbonate 1260 mg (Calcichew Shire Pharmaceuticals Ltd). Given at a third of the daily number of …
In a group of seven patients, we have compared Titralac with two alternative preparations containing calcium carbonate 1250 mg (Calci …
Effects of three antacids on the bioavailability of valproic acid.
May CA, Garnett WR, Small RE, Pellock JM. May CA, et al. Clin Pharm. 1982 May-Jun;1(3):244-7. Clin Pharm. 1982. PMID: 6821035
Specifically, equal neutralizing capacity doses of 160 meq of Maalox (62 ml), Trisogel (97 ml), or Titralac (42 ml) were administered one and three hours after meals and at bedtime on the same day. ...
Specifically, equal neutralizing capacity doses of 160 meq of Maalox (62 ml), Trisogel (97 ml), or Titralac (42 ml) were administered …