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2020 9
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2024 260

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Did you mean toxin amran (4 results)?
Lipids and Lipid Derivatives for RNA Delivery.
Zhang Y, Sun C, Wang C, Jankovic KE, Dong Y. Zhang Y, et al. Chem Rev. 2021 Oct 27;121(20):12181-12277. doi: 10.1021/acs.chemrev.1c00244. Epub 2021 Jul 19. Chem Rev. 2021. PMID: 34279087 Free PMC article. Review.
The dawn of mRNA vaccines: The COVID-19 case.
Verbeke R, Lentacker I, De Smedt SC, Dewitte H. Verbeke R, et al. J Control Release. 2021 May 10;333:511-520. doi: 10.1016/j.jconrel.2021.03.043. Epub 2021 Mar 30. J Control Release. 2021. PMID: 33798667 Free PMC article. Review.
In less than one year since the outbreak of the COVID-19 pandemic, two mRNA-based vaccines, BNT162b2 and mRNA-1273, were granted the first historic authorization for emergency use, while another mRNA vaccine, CVnCoV, progressed to phase 3 clinical testing. The COVID-19 mRN …
In less than one year since the outbreak of the COVID-19 pandemic, two mRNA-based vaccines, BNT162b2 and mRNA-1273, were granted the first h …
Safety and Efficacy of a Third Dose of BNT162b2 Covid-19 Vaccine.
Moreira ED Jr, Kitchin N, Xu X, Dychter SS, Lockhart S, Gurtman A, Perez JL, Zerbini C, Dever ME, Jennings TW, Brandon DM, Cannon KD, Koren MJ, Denham DS, Berhe M, Fitz-Patrick D, Hammitt LL, Klein NP, Nell H, Keep G, Wang X, Koury K, Swanson KA, Cooper D, Lu C, Türeci Ö, Lagkadinou E, Tresnan DB, Dormitzer PR, Şahin U, Gruber WC, Jansen KU; C4591031 Clinical Trial Group. Moreira ED Jr, et al. N Engl J Med. 2022 May 19;386(20):1910-1921. doi: 10.1056/NEJMoa2200674. Epub 2022 Mar 23. N Engl J Med. 2022. PMID: 35320659 Free PMC article. Clinical Trial.
We assessed vaccine safety and efficacy against Covid-19 starting 7 days after the third dose. ...CONCLUSIONS: A third dose of the BNT162b2 vaccine administered a median of 10.8 months after the second dose provided 95.3% efficacy against Covid-19 as compared with t …
We assessed vaccine safety and efficacy against Covid-19 starting 7 days after the third dose. ...CONCLUSIONS: A third dose of the BN …
N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting.
Mulroney TE, Pöyry T, Yam-Puc JC, Rust M, Harvey RF, Kalmar L, Horner E, Booth L, Ferreira AP, Stoneley M, Sawarkar R, Mentzer AJ, Lilley KS, Smales CM, von der Haar T, Turtle L, Dunachie S, Klenerman P, Thaventhiran JED, Willis AE. Mulroney TE, et al. Nature. 2024 Jan;625(7993):189-194. doi: 10.1038/s41586-023-06800-3. Epub 2023 Dec 6. Nature. 2024. PMID: 38057663 Free PMC article.
Here we demonstrate that incorporation of N(1)-methylpseudouridine into mRNA results in +1 ribosomal frameshifting in vitro and that cellular immunity in mice and humans to +1 frameshifted products from BNT162b2 vaccine mRNA translation occurs after vaccination. The +1 rib …
Here we demonstrate that incorporation of N(1)-methylpseudouridine into mRNA results in +1 ribosomal frameshifting in vitro and that cellula …
Impact of tozinameran (BNT162b2) mRNA vaccine on kidney transplant and chronic dialysis patients: 3-5 months follow-up.
Ben-Dov IZ, Oster Y, Tzukert K, Alster T, Bader R, Israeli R, Asayag H, Aharon M, Burstein I, Pri-Chen H, Imam A, Abel R, Mor-Yosef Levi I, Khalaileh A, Oiknine-Djian E, Bloch A, Wolf DG, Dranitzki Elhalel M. Ben-Dov IZ, et al. J Nephrol. 2022 Jan;35(1):153-164. doi: 10.1007/s40620-021-01210-y. Epub 2022 Jan 6. J Nephrol. 2022. PMID: 34988942 Free PMC article.
BACKGROUND: Determining the humoral immunogenicity of tozinameran (BNT162b2) in patients requiring chronic renal replacement therapy, and its impact on COVID-19 morbidity several months after vaccination, may guide risk assessment and changes in vaccination policy. METHODS …
BACKGROUND: Determining the humoral immunogenicity of tozinameran (BNT162b2) in patients requiring chronic renal replacement therapy, …
4,053 results