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1951 6
1952 5
1953 9
1954 11
1955 6
1956 5
1957 5
1958 7
1959 2
1960 4
1961 7
1962 8
1963 20
1964 28
1965 32
1966 18
1967 57
1968 37
1969 47
1970 33
1971 36
1972 43
1973 48
1974 51
1975 57
1976 46
1977 49
1978 47
1979 42
1980 47
1981 62
1982 59
1983 63
1984 63
1985 51
1986 45
1987 62
1988 53
1989 66
1990 78
1991 79
1992 110
1993 142
1994 200
1995 231
1996 249
1997 239
1998 233
1999 240
2000 240
2001 209
2002 209
2003 231
2004 279
2005 306
2006 354
2007 387
2008 391
2009 461
2010 487
2011 497
2012 569
2013 548
2014 580
2015 637
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2017 715
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2019 788
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The following term was not found in PubMed: tripeptide-9
Page 1
Therapeutic Potential of Citrulline as an Arginine Supplement: A Clinical Pharmacology Review.
Rashid J, Kumar SS, Job KM, Liu X, Fike CD, Sherwin CMT. Rashid J, et al. Paediatr Drugs. 2020 Jun;22(3):279-293. doi: 10.1007/s40272-020-00384-5. Paediatr Drugs. 2020. PMID: 32140997 Free PMC article. Review.
Although not yet well-studied, arginine/citrulline has immense therapeutic potential in some life-threatening diseases in children. ...The pharmacology of arginine/citrulline is confounded by several patient-specific factors such as variations in baseline arginine/ …
Although not yet well-studied, arginine/citrulline has immense therapeutic potential in some life-threatening diseases in children. . …
A critical review of citrulline malate supplementation and exercise performance.
Gough LA, Sparks SA, McNaughton LR, Higgins MF, Newbury JW, Trexler E, Faghy MA, Bridge CA. Gough LA, et al. Eur J Appl Physiol. 2021 Dec;121(12):3283-3295. doi: 10.1007/s00421-021-04774-6. Epub 2021 Aug 21. Eur J Appl Physiol. 2021. PMID: 34417881 Free PMC article. Review.
As a nitric oxide (NO) enhancer, citrulline malate (CM) has recently been touted as a potential ergogenic aid to both resistance and high-intensity exercise performance, as well as the recovery of muscular performance. ...Reasons for the disparity in conclusions seem to be …
As a nitric oxide (NO) enhancer, citrulline malate (CM) has recently been touted as a potential ergogenic aid to both resistance and …
Citrullination in Cancer.
Yuzhalin AE. Yuzhalin AE. Cancer Res. 2019 Apr 1;79(7):1274-1284. doi: 10.1158/0008-5472.CAN-18-2797. Epub 2019 Mar 20. Cancer Res. 2019. PMID: 30894374 Review.
This article summarizes and critically reviews the influence of citrullination on different aspects of tumor biology, including (i) regulation of apoptosis and differentiation, (ii) promoting EMT and metastasis, and (iii) potential use of citrullinated antigens for …
This article summarizes and critically reviews the influence of citrullination on different aspects of tumor biology, including (i) r …
Protein citrullination: inhibition, identification and insertion.
Barasa L, Thompson PR. Barasa L, et al. Philos Trans R Soc Lond B Biol Sci. 2023 Nov 20;378(1890):20220240. doi: 10.1098/rstb.2022.0240. Epub 2023 Oct 2. Philos Trans R Soc Lond B Biol Sci. 2023. PMID: 37778377 Review.
Notably, citrullinated proteins may serve more generally as biomarkers of specific disease states; however, the identification of citrullinated protein residues remains challenging owing to the small 1 Da mass change that occurs upon citrullination. Herein, w …
Notably, citrullinated proteins may serve more generally as biomarkers of specific disease states; however, the identification of …
PAD2: A potential target for tumor therapy.
Teng Y, Chen Y, Tang X, Wang S, Yin K. Teng Y, et al. Biochim Biophys Acta Rev Cancer. 2023 Sep;1878(5):188931. doi: 10.1016/j.bbcan.2023.188931. Epub 2023 Jun 12. Biochim Biophys Acta Rev Cancer. 2023. PMID: 37315720 Review.
Peptide arginine deiminase 2(PAD2) catalyzes the conversion of arginine residues on target proteins to citrulline residues in the presence of calcium ions. This particular posttranslational modification is called citrullination. PAD2 can regulate the transcriptional …
Peptide arginine deiminase 2(PAD2) catalyzes the conversion of arginine residues on target proteins to citrulline residues in the pre …
Citrullination and autoimmunity.
Valesini G, Gerardi MC, Iannuccelli C, Pacucci VA, Pendolino M, Shoenfeld Y. Valesini G, et al. Autoimmun Rev. 2015 Jun;14(6):490-7. doi: 10.1016/j.autrev.2015.01.013. Epub 2015 Jan 28. Autoimmun Rev. 2015. PMID: 25636595 Review.
Nonetheless, citrullination has been reported to be a process present in a wide range of inflammatory tissues. ...Moreover, environmental exposure to cigarette smoke and nanomaterials of air pollution may be able to induce citrullination in lung cells prior to any d …
Nonetheless, citrullination has been reported to be a process present in a wide range of inflammatory tissues. ...Moreover, environme …
Rheumatoid arthritis and citrullination.
Darrah E, Andrade F. Darrah E, et al. Curr Opin Rheumatol. 2018 Jan;30(1):72-78. doi: 10.1097/BOR.0000000000000452. Curr Opin Rheumatol. 2018. PMID: 28937414 Free PMC article. Review.
PURPOSE OF REVIEW: Dysregulated citrullination is a key element that drives the production and maintenance of antibodies to citrullinated proteins, a hallmark in rheumatoid arthritis (RA). ...SUMMARY: Citrullinating enzymes (peptidylarginine deiminases, PADs) …
PURPOSE OF REVIEW: Dysregulated citrullination is a key element that drives the production and maintenance of antibodies to citrul
Characterizing citrullination by mass spectrometry-based proteomics.
Rebak AS, Hendriks IA, Nielsen ML. Rebak AS, et al. Philos Trans R Soc Lond B Biol Sci. 2023 Nov 20;378(1890):20220237. doi: 10.1098/rstb.2022.0237. Epub 2023 Oct 2. Philos Trans R Soc Lond B Biol Sci. 2023. PMID: 37778389 Free PMC article. Review.
Here we will outline contemporary methods and current challenges for studying citrullination by MS, and discuss how the development of neoteric citrullination-specific proteomics approaches still may improve our understanding of citrullination networks. This …
Here we will outline contemporary methods and current challenges for studying citrullination by MS, and discuss how the development o …
PADs and NETs in digestive system: From physiology to pathology.
Song YH, Wang ZJ, Kang L, He ZX, Zhao SB, Fang X, Li ZS, Wang SL, Bai Y. Song YH, et al. Front Immunol. 2023 Jan 24;14:1077041. doi: 10.3389/fimmu.2023.1077041. eCollection 2023. Front Immunol. 2023. PMID: 36761761 Free PMC article. Review.
Peptidylarginine deiminases (PADs) are the only enzyme class known to deiminate arginine residues into citrulline in proteins, a process known as citrullination. This is an important post-translational modification that functions in several physiological and patholo …
Peptidylarginine deiminases (PADs) are the only enzyme class known to deiminate arginine residues into citrulline in proteins, a proc …
Pitfalls in the detection of citrullination and carbamylation.
Verheul MK, van Veelen PA, van Delft MAM, de Ru A, Janssen GMC, Rispens T, Toes REM, Trouw LA. Verheul MK, et al. Autoimmun Rev. 2018 Feb;17(2):136-141. doi: 10.1016/j.autrev.2017.11.017. Epub 2017 Dec 2. Autoimmun Rev. 2018. PMID: 29203292 Free article. Review.
Carbamylation is the chemical modification of a lysine into a homocitrulline, whereas citrullination is an enzymatic conversion of an arginine into a citrulline. ...We observed that some antibodies are able to distinguish between carbamylation and citrullination
Carbamylation is the chemical modification of a lysine into a homocitrulline, whereas citrullination is an enzymatic conversion of an …
14,488 results
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