Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1976 1
1978 1
1979 1
1980 1
1981 1
1982 3
1983 2
1984 3
1985 1
1986 1
1987 3
1988 2
1989 11
1990 1
1991 1
1992 1
1993 2
1994 5
1996 4
1997 1
1999 1
2000 1
2001 1
2002 1
2003 1
2006 1
2012 1
2020 1
2021 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

56 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Efficacy of Triprolidine in the Treatment of Temporary Sleep Disturbance.
Cravo AS, Shephard A, Shea T. Cravo AS, et al. J Clin Pharmacol. 2021 Sep;61(9):1156-1164. doi: 10.1002/jcph.1861. Epub 2021 Apr 22. J Clin Pharmacol. 2021. PMID: 33768603 Clinical Trial.
Patients aged 18 years old were randomized 1:1:1 to receive either triprolidine 2.5 mg (n = 65), triprolidine 5 mg (n = 66), or placebo (n = 67) on 3 consecutive nights. ...Sleep latency was significantly improved for triprolidine 2.5 mg versus placebo on nig …
Patients aged 18 years old were randomized 1:1:1 to receive either triprolidine 2.5 mg (n = 65), triprolidine 5 mg (n = 66), o …
Bioavailability of Triprolidine as a Single Agent or in Combination With Pseudoephedrine: A Randomized, Open-Label Crossover Study in Healthy Volunteers.
Febbraro S, Shea T, Cravo AS. Febbraro S, et al. Clin Pharmacol Drug Dev. 2020 May;9(4):486-495. doi: 10.1002/cpdd.777. Epub 2020 Mar 4. Clin Pharmacol Drug Dev. 2020. PMID: 32133778 Free PMC article. Clinical Trial.
This phase 1 single-center open-label, randomized, single-dose, 3-way crossover trial evaluated the PK profiles of 2 doses of film-coated triprolidine caplets (2.5 and 5 mg) compared with a reference combination tablet (triprolidine 2.5 mg + pseudoephedrine 60 mg) i …
This phase 1 single-center open-label, randomized, single-dose, 3-way crossover trial evaluated the PK profiles of 2 doses of film-coated …
Effects of pseudoephedrine and triprolidine, alone and in combination, on symptoms of the common cold.
Bye CE, Cooper J, Empey DW, Fowle AS, Hughes DT, Letley E, O'Grady J. Bye CE, et al. Br Med J. 1980 Jul 19;281(6234):189-90. doi: 10.1136/bmj.281.6234.189. Br Med J. 1980. PMID: 6996784 Free PMC article. Clinical Trial.
A total of 466 healthy adults from four different regions of England entered a double-blind, randomised trial to test the effectiveness of an antihistamine (triprolidine) and a decongestant (pseudoephedrine), alone or in combination, in relieving symptoms of the common col …
A total of 466 healthy adults from four different regions of England entered a double-blind, randomised trial to test the effectiveness of a …
Effects of triprolidine and dipipanone in the cold induced pain test, and the central nervous system of healthy volunteers.
Telekes A, Holland RL, Withington DA, Peck AW. Telekes A, et al. Br J Clin Pharmacol. 1987 Jul;24(1):43-50. doi: 10.1111/j.1365-2125.1987.tb03134.x. Br J Clin Pharmacol. 1987. PMID: 3620284 Free PMC article. Clinical Trial.
1 Twelve healthy volunteers took part in a study of the interaction between the antihistamine triprolidine and the opioid dipipanone in the cold induced pain (CP) test and tests of sedation. They received placebo, triprolidine 2.5 mg, dipipanone 8 mg or the combinat …
1 Twelve healthy volunteers took part in a study of the interaction between the antihistamine triprolidine and the opioid dipipanone …
Effect of the antihistamines, brompheniramine maleate and triprolidine hydrochloride, on performance in man.
Nicholson AN. Nicholson AN. Br J Clin Pharmacol. 1979 Oct;8(4):321-4. doi: 10.1111/j.1365-2125.1979.tb04712.x. Br J Clin Pharmacol. 1979. PMID: 508506 Free PMC article. Clinical Trial.
1 Effects of brompheniramine maleate (4 and 12 mg) and triprolidine hydrochloride (2.5 and 10 mg) on visuo-motor coordination, and on subjective assessments of performance, well-being and sleep were each studied in six subjects at 0.5, 1.5, 3.0, 5.0 and 7.0 h after ingesti …
1 Effects of brompheniramine maleate (4 and 12 mg) and triprolidine hydrochloride (2.5 and 10 mg) on visuo-motor coordination, and on …
The effects of single and repeated administration of ebastine on cognition and psychomotor performance in comparison to triprolidine and placebo in healthy volunteers.
Hindmarch, Shamsi Z. Hindmarch, et al. Curr Med Res Opin. 2001;17(4):273-81. Curr Med Res Opin. 2001. PMID: 11922401 Clinical Trial.

However, as expected for a positive internal control, a number of objective measures were significantly disrupted by triprolidine (p < 0.05). Triprolidine produced an overall increase of the peripheral reaction time component of the simulated car tracking task (S

…
However, as expected for a positive internal control, a number of objective measures were significantly disrupted by triprolidine (p …
Histamine challenge and anterior nasal rhinometry: their use in the assessment of pseudoephedrine and triprolidine as nasal decongestants in subjects with hayfever.
Britton MG, Empey DW, John GC, McDonnell KA, Hughes DT. Britton MG, et al. Br J Clin Pharmacol. 1978 Jul;6(1):51-8. doi: 10.1111/j.1365-2125.1978.tb01681.x. Br J Clin Pharmacol. 1978. PMID: 78718 Free PMC article. Clinical Trial.
Measurements before and after challenge with three concentrations of histamine diphosphate showed significant rises in NAR for each challenge. 2 In a double-blind, crossover study with the same patients triprolidine (2.5 mg) and pseudoephedrine (60 mg) were shown to be equ …
Measurements before and after challenge with three concentrations of histamine diphosphate showed significant rises in NAR for each challeng …
Bioavailability of pseudoephedrine and triprolidine from combination and single-ingredient products.
Williams BO, Liao SH, Lai AA, Arnold JD, Perkins JG, Blum MR, Findlay JW. Williams BO, et al. Clin Pharm. 1984 Nov-Dec;3(6):638-43. Clin Pharm. 1984. PMID: 6509877 Clinical Trial.
The bioavailability of pseudoephedrine and triprolidine from combination and single-ingredient products was evaluated in a randomized, four-way crossover study. ...For both pseudoephedrine and triprolidine, the combination tablet was bioequivalent to the syrup and t …
The bioavailability of pseudoephedrine and triprolidine from combination and single-ingredient products was evaluated in a randomized …
Acute and subchronic effects of the H1-histamine receptor antagonist ebastine in 10, 20 and 30 mg dose, and triprolidine 10 mg on car driving performance.
Brookhuis KA, De Vries G, De Waard D. Brookhuis KA, et al. Br J Clin Pharmacol. 1993 Jul;36(1):67-70. doi: 10.1111/j.1365-2125.1993.tb05894.x. Br J Clin Pharmacol. 1993. PMID: 8104017 Free PMC article. Clinical Trial.
The study was double-blind, placebo controlled and included the antihistamine triprolidine (10 mg sustained release) as an active drug control. 2. ...Triprolidine (10 mg) significantly increased both the amount of weaving and the delay in following speed manoeuvres …
The study was double-blind, placebo controlled and included the antihistamine triprolidine (10 mg sustained release) as an active dru …
Comparison of the effects of astemizole/pseudoephedrine and triprolidine/pseudoephedrine on CNS activity and psychomotor function.
Stanley N, Alford CA, Rombaut NE, Hindmarch I. Stanley N, et al. Int Clin Psychopharmacol. 1996 Mar;11(1):31-6. doi: 10.1097/00004850-199603000-00004. Int Clin Psychopharmacol. 1996. PMID: 8732311 Clinical Trial.
The sedative properties of astemizole-D and triprolidine-D were compared in a double-blind, placebo-controlled, repeated-measures design study comprising three experimental treatments, each with a duration of 2 days (n = 12). ...Also, when scores were summed across all tim …
The sedative properties of astemizole-D and triprolidine-D were compared in a double-blind, placebo-controlled, repeated-measures des …
56 results

Searches related to "triprolidine"