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A DNA-PKcs mutation in a radiosensitive T-B- SCID patient inhibits Artemis activation and nonhomologous end-joining.
van der Burg M, Ijspeert H, Verkaik NS, Turul T, Wiegant WW, Morotomi-Yano K, Mari PO, Tezcan I, Chen DJ, Zdzienicka MZ, van Dongen JJ, van Gent DC. van der Burg M, et al. Among authors: van dongen jj, van gent dc. J Clin Invest. 2009 Jan;119(1):91-8. doi: 10.1172/JCI37141. Epub 2008 Dec 15. J Clin Invest. 2009. PMID: 19075392 Free PMC article.
Molecular mechanisms of DNA double strand break repair.
Kanaar R, Hoeijmakers JH, van Gent DC. Kanaar R, et al. Among authors: van gent dc. Trends Cell Biol. 1998 Dec;8(12):483-9. doi: 10.1016/s0962-8924(98)01383-x. Trends Cell Biol. 1998. PMID: 9861670 Review.
Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre-B-cell receptor checkpoint in bone marrow.
Noordzij JG, Verkaik NS, van der Burg M, van Veelen LR, de Bruin-Versteeg S, Wiegant W, Vossen JM, Weemaes CM, de Groot R, Zdzienicka MZ, van Gent DC, van Dongen JJ. Noordzij JG, et al. Among authors: van dongen jj, van gent dc, van veelen lr, van der burg m. Blood. 2003 Feb 15;101(4):1446-52. doi: 10.1182/blood-2002-01-0187. Epub 2002 Oct 24. Blood. 2003. PMID: 12406895 Free article.
The role of DNA dependent protein kinase in synapsis of DNA ends.
Weterings E, Verkaik NS, Brüggenwirth HT, Hoeijmakers JH, van Gent DC. Weterings E, et al. Among authors: van gent dc. Nucleic Acids Res. 2003 Dec 15;31(24):7238-46. doi: 10.1093/nar/gkg889. Nucleic Acids Res. 2003. PMID: 14654699 Free PMC article.
112 results