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The BH4 domain of anti-apoptotic Bcl-XL, but not that of the related Bcl-2, limits the voltage-dependent anion channel 1 (VDAC1)-mediated transfer of pro-apoptotic Ca2+ signals to mitochondria.
Monaco G, Decrock E, Arbel N, van Vliet AR, La Rovere RM, De Smedt H, Parys JB, Agostinis P, Leybaert L, Shoshan-Barmatz V, Bultynck G. Monaco G, et al. Among authors: van vliet ar. J Biol Chem. 2015 Apr 3;290(14):9150-61. doi: 10.1074/jbc.M114.622514. Epub 2015 Feb 13. J Biol Chem. 2015. PMID: 25681439 Free PMC article.
The ER Stress Sensor PERK Coordinates ER-Plasma Membrane Contact Site Formation through Interaction with Filamin-A and F-Actin Remodeling.
van Vliet AR, Giordano F, Gerlo S, Segura I, Van Eygen S, Molenberghs G, Rocha S, Houcine A, Derua R, Verfaillie T, Vangindertael J, De Keersmaecker H, Waelkens E, Tavernier J, Hofkens J, Annaert W, Carmeliet P, Samali A, Mizuno H, Agostinis P. van Vliet AR, et al. Among authors: van eygen s. Mol Cell. 2017 Mar 2;65(5):885-899.e6. doi: 10.1016/j.molcel.2017.01.020. Epub 2017 Feb 23. Mol Cell. 2017. PMID: 28238652 Free article.
Mitochondria-Associated Membranes and ER Stress.
van Vliet AR, Agostinis P. van Vliet AR, et al. Curr Top Microbiol Immunol. 2018;414:73-102. doi: 10.1007/82_2017_2. Curr Top Microbiol Immunol. 2018. PMID: 28349285 Review.
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