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A Phase I Trial of the Dual MET Kinase/OCT-2 Inhibitor OMO-1 in Metastatic Solid Malignancies Including MET Exon 14 Mutated Lung Cancer.
Pruis MA, Krebs MG, Plummer R, De Vos F, Angevin E, Prenen H, Forster MD, Clack G, Van der Aa A, Tjwa M, Jansen E, Perera T, Lolkema MP. Pruis MA, et al. Among authors: van der aa a. Oncologist. 2023 Dec 11;28(12):e1248-e1258. doi: 10.1093/oncolo/oyad146. Oncologist. 2023. PMID: 37260332 Free PMC article. Clinical Trial.
CXCR4 as a novel target in immunology: moving away from typical antagonists.
Caspar B, Cocchiara P, Melet A, Van Emelen K, Van der Aa A, Milligan G, Herbeuval JP. Caspar B, et al. Among authors: van der aa a. Future Drug Discov. 2022 Jun;4(2):FDD77. doi: 10.4155/fdd-2022-0007. Epub 2022 Jul 19. Future Drug Discov. 2022. PMID: 35875591 Free PMC article. Review.
Response to Placebo, Measured by Endoscopic Evaluation of Crohn's Disease Activity, in a Pooled Analysis of Data From 5 Randomized Controlled Induction Trials.
Duijvestein M, Jeyarajah J, Guizzetti L, Zou G, Parker CE, van Viegen T, VandeCasteele N, Khanna R, Van Der Aa A, Sandborn WJ, Feagan BG, D'Haens GR, Jairath V. Duijvestein M, et al. Among authors: van der aa a. Clin Gastroenterol Hepatol. 2020 May;18(5):1121-1132.e2. doi: 10.1016/j.cgh.2019.08.025. Epub 2019 Aug 20. Clin Gastroenterol Hepatol. 2020. PMID: 31442599
Efficacy and safety of filgotinib, a selective Janus kinase 1 inhibitor, in patients with active psoriatic arthritis (EQUATOR): results from a randomised, placebo-controlled, phase 2 trial.
Mease P, Coates LC, Helliwell PS, Stanislavchuk M, Rychlewska-Hanczewska A, Dudek A, Abi-Saab W, Tasset C, Meuleners L, Harrison P, Besuyen R, Van der Aa A, Mozaffarian N, Greer JM, Kunder R, Van den Bosch F, Gladman DD. Mease P, et al. Among authors: van der aa a. Lancet. 2018 Dec 1;392(10162):2367-2377. doi: 10.1016/S0140-6736(18)32483-8. Epub 2018 Oct 22. Lancet. 2018. PMID: 30360969 Free article. Clinical Trial.
32 results