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An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria.
Andressoo JO, Mitchell JR, de Wit J, Hoogstraten D, Volker M, Toussaint W, Speksnijder E, Beems RB, van Steeg H, Jans J, de Zeeuw CI, Jaspers NG, Raams A, Lehmann AR, Vermeulen W, Hoeijmakers JH, van der Horst GT. Andressoo JO, et al. Among authors: van der horst gt, van steeg h. Cancer Cell. 2006 Aug;10(2):121-32. doi: 10.1016/j.ccr.2006.05.027. Cancer Cell. 2006. PMID: 16904611 Free article.
DNA damage and ageing: new-age ideas for an age-old problem.
Garinis GA, van der Horst GT, Vijg J, Hoeijmakers JH. Garinis GA, et al. Among authors: van der horst gt. Nat Cell Biol. 2008 Nov;10(11):1241-7. doi: 10.1038/ncb1108-1241. Nat Cell Biol. 2008. PMID: 18978832 Free PMC article. Review.
Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity.
Garinis GA, Uittenboogaard LM, Stachelscheid H, Fousteri M, van Ijcken W, Breit TM, van Steeg H, Mullenders LH, van der Horst GT, Brüning JC, Niessen CM, Hoeijmakers JH, Schumacher B. Garinis GA, et al. Among authors: van der horst gt, van steeg h, van ijcken w. Nat Cell Biol. 2009 May;11(5):604-15. doi: 10.1038/ncb1866. Epub 2009 Apr 12. Nat Cell Biol. 2009. PMID: 19363488 Free PMC article.
174 results