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ParB proteins can bypass DNA-bound roadblocks via dimer-dimer recruitment.
Tišma M, Panoukidou M, Antar H, Soh YM, Barth R, Pradhan B, Barth A, van der Torre J, Michieletto D, Gruber S, Dekker C. Tišma M, et al. Among authors: van der torre j. Sci Adv. 2022 Jul;8(26):eabn3299. doi: 10.1126/sciadv.abn3299. Epub 2022 Jun 29. Sci Adv. 2022. PMID: 35767606 Free PMC article.
Condensin-driven loop extrusion on supercoiled DNA.
Kim E, Gonzalez AM, Pradhan B, van der Torre J, Dekker C. Kim E, et al. Among authors: van der torre j. Nat Struct Mol Biol. 2022 Jul;29(7):719-727. doi: 10.1038/s41594-022-00802-x. Epub 2022 Jul 14. Nat Struct Mol Biol. 2022. PMID: 35835864
SMC complexes can traverse physical roadblocks bigger than their ring size.
Pradhan B, Barth R, Kim E, Davidson IF, Bauer B, van Laar T, Yang W, Ryu JK, van der Torre J, Peters JM, Dekker C. Pradhan B, et al. Among authors: van der torre j. Cell Rep. 2022 Oct 18;41(3):111491. doi: 10.1016/j.celrep.2022.111491. Cell Rep. 2022. PMID: 36261017 Free article.
CTCF is a DNA-tension-dependent barrier to cohesin-mediated loop extrusion.
Davidson IF, Barth R, Zaczek M, van der Torre J, Tang W, Nagasaka K, Janissen R, Kerssemakers J, Wutz G, Dekker C, Peters JM. Davidson IF, et al. Among authors: van der torre j. Nature. 2023 Apr;616(7958):822-827. doi: 10.1038/s41586-023-05961-5. Epub 2023 Apr 19. Nature. 2023. PMID: 37076620 Free PMC article.
24 results