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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 1
1985 1
1986 2
1987 1
1988 1
1990 2
1992 1
1996 1
1997 4
1998 4
1999 2
2000 3
2001 1
2002 2
2003 5
2004 2
2005 5
2006 6
2007 8
2008 6
2009 6
2010 4
2011 8
2012 3
2013 6
2014 4
2015 4
2016 3
2017 5
2018 3
2019 2
2020 6
2021 6
2022 3
2023 2
2024 4

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118 results

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Page 1
HIV-1 reverse transcription.
Hu WS, Hughes SH. Hu WS, et al. Cold Spring Harb Perspect Med. 2012 Oct 1;2(10):a006882. doi: 10.1101/cshperspect.a006882. Cold Spring Harb Perspect Med. 2012. PMID: 23028129 Free PMC article. Review.
Reverse transcription and integration are the defining features of the Retroviridae; the common name "retrovirus" derives from the fact that these viruses use a virally encoded enzyme, reverse transcriptase (RT), to convert their RNA genomes into DNA. Reverse transcription is an …
Reverse transcription and integration are the defining features of the Retroviridae; the common name "retrovirus" derives from the fact that …
HIV-1 RNA genome packaging: it's G-rated.
Duchon A, Hu W-S. Duchon A, et al. mBio. 2024 Apr 10;15(4):e0086123. doi: 10.1128/mbio.00861-23. Epub 2024 Feb 27. mBio. 2024. PMID: 38411060 Free PMC article. Review.
A member of the Retroviridae, human immunodeficiency virus type 1 (HIV-1), uses the RNA genome packaged into nascent virions to transfer genetic information to its progeny. ...Thus, during virus assembly HIV-1 can identify and selectively encapsidate HIV-1 unspliced …
A member of the Retroviridae, human immunodeficiency virus type 1 (HIV-1), uses the RNA genome packaged into nascent virions to trans …
Mechanisms and factors that influence high frequency retroviral recombination.
Delviks-Frankenberry K, Galli A, Nikolaitchik O, Mens H, Pathak VK, Hu WS. Delviks-Frankenberry K, et al. Among authors: hu ws. Viruses. 2011 Sep;3(9):1650-1680. doi: 10.3390/v3091650. Epub 2011 Sep 9. Viruses. 2011. PMID: 21994801 Free PMC article. Review.
This review summarizes our current understanding of the factors and mechanisms influencing retroviral recombination, fidelity of the recombination process, and evaluates the subsequent viral diversity and fitness of the progeny recombinant. ...
This review summarizes our current understanding of the factors and mechanisms influencing retroviral recombination, fidelity of the …
Life of psi: how full-length HIV-1 RNAs become packaged genomes in the viral particles.
Kuzembayeva M, Dilley K, Sardo L, Hu WS. Kuzembayeva M, et al. Among authors: hu ws. Virology. 2014 Apr;454-455:362-70. doi: 10.1016/j.virol.2014.01.019. Epub 2014 Feb 14. Virology. 2014. PMID: 24530126 Free PMC article. Review.
The full-length HIV-1 RNA plays a central role in viral replication as it serves as the genome in the progeny virus and is used as the template for Gag and GagPol translation. ...
The full-length HIV-1 RNA plays a central role in viral replication as it serves as the genome in the progeny virus and is used as th …
HIV-1 usurps transcription start site heterogeneity of host RNA polymerase II to maximize replication fitness.
Nikolaitchik OA, Islam S, Kitzrow JP, Duchon A, Cheng Z, Liu Y, Rawson JMO, Shao W, Nikolaitchik M, Kearney MF, Maldarelli F, Musier-Forsyth K, Pathak VK, Hu WS. Nikolaitchik OA, et al. Among authors: hu ws. Proc Natl Acad Sci U S A. 2023 Jun 6;120(23):e2305103120. doi: 10.1073/pnas.2305103120. Epub 2023 May 30. Proc Natl Acad Sci U S A. 2023. PMID: 37252967 Free PMC article.
However, both mutants exhibit replication defects compared to the wild-type virus. The 3G-RNA-expressing mutant displays an RNA genome-packaging defect and delayed replication kinetics, whereas the 1G-RNA-expressing mutant exhibits reduced Gag expression and a replication …
However, both mutants exhibit replication defects compared to the wild-type virus. The 3G-RNA-expressing mutant displays an RNA genom …
Retroviral recombination: review of genetic analyses.
Hu WS, Rhodes T, Dang Q, Pathak V. Hu WS, et al. Front Biosci. 2003 Jan 1;8:d143-55. doi: 10.2741/940. Front Biosci. 2003. PMID: 12456341 Review.
Because two copies of RNA are present in one virion, it is possible for RT to switch from one copy of the viral RNA to the other copy during DNA synthesis, thereby generating a recombinant containing some genetic information from each of the RNAs. Recombination occurs at high fre …
Because two copies of RNA are present in one virion, it is possible for RT to switch from one copy of the viral RNA to the other copy during …
Retroviral mutation rates and reverse transcriptase fidelity.
Svarovskaia ES, Cheslock SR, Zhang WH, Hu WS, Pathak VK. Svarovskaia ES, et al. Among authors: hu ws. Front Biosci. 2003 Jan 1;8:d117-34. doi: 10.2741/957. Front Biosci. 2003. PMID: 12456349 Review.
Genetic variation in retroviral populations provides a mechanism for retroviruses to escape host immune responses and develop resistance to all known antiretroviral drugs. ...An overview of in vivo and in vitro studies of retroviral mutation rates determined by vari …
Genetic variation in retroviral populations provides a mechanism for retroviruses to escape host immune responses and develop resista …
APOBEC3 proteins can copackage and comutate HIV-1 genomes.
Desimmie BA, Burdick RC, Izumi T, Doi H, Shao W, Alvord WG, Sato K, Koyanagi Y, Jones S, Wilson E, Hill S, Maldarelli F, Hu WS, Pathak VK. Desimmie BA, et al. Among authors: hu ws. Nucleic Acids Res. 2016 Sep 19;44(16):7848-65. doi: 10.1093/nar/gkw653. Epub 2016 Jul 20. Nucleic Acids Res. 2016. PMID: 27439715 Free PMC article.
118 results