Formaldehyde as a probe of DNA structure. II. Reaction with endocyclic imino groups of DNA bases.
McGhee JD, von Hippel PH.
McGhee JD, et al. Among authors: von hippel ph.
Biochemistry. 1975 Mar 25;14(6):1297-303. doi: 10.1021/bi00677a030.
Biochemistry. 1975.
PMID: 235286
The main results are: (i) the equilibrium constants for forming a hydroxymethyl adduct remain quite constant at about 2-2.5 (M-1) for all the compounds studied, independent of their pK; (ii) both forward and reverse rate constants with 5'-TMP are specific base catalyzed in the …
The main results are: (i) the equilibrium constants for forming a hydroxymethyl adduct remain quite constant at about 2-2.5 (M-1) for all th …