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Synthesis and evaluation of 4-O-alkylated 2-deoxy-2,3-didehydro-N-acetylneuraminic acid derivatives as inhibitors of human parainfluenza virus type-3 sialidase activity.
Tindal DJ, Dyason JC, Thomson RJ, Suzuki T, Ueyama H, Kuwahara Y, Maki N, Suzuki Y, von Itzstein M. Tindal DJ, et al. Among authors: von itzstein m. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1655-8. doi: 10.1016/j.bmcl.2006.12.105. Epub 2007 Jan 8. Bioorg Med Chem Lett. 2007. PMID: 17236768
The approved pediatric drug suramin identified as a clinical candidate for the treatment of EV71 infection-suramin inhibits EV71 infection in vitro and in vivo.
Ren P, Zou G, Bailly B, Xu S, Zeng M, Chen X, Shen L, Zhang Y, Guillon P, Arenzana-Seisdedos F, Buchy P, Li J, von Itzstein M, Li Q, Altmeyer R. Ren P, et al. Among authors: von itzstein m. Emerg Microbes Infect. 2014 Sep;3(9):e62. doi: 10.1038/emi.2014.60. Epub 2014 Sep 3. Emerg Microbes Infect. 2014. PMID: 26038755 Free PMC article.
239 results