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1981 2
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1983 2
1984 3
1985 2
1986 2
1987 3
1988 3
1989 3
1990 5
1991 1
1992 2
1993 4
1994 4
1995 9
1996 1
1997 5
1998 7
1999 5
2000 1
2001 11
2002 8
2003 6
2004 2
2005 9
2006 6
2007 3
2008 6
2009 3
2010 7
2011 3
2012 2
2013 4
2014 3
2015 3
2016 4
2017 7
2018 3
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2020 5
2021 16
2022 7
2023 12
2024 3

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194 results

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Page 1
Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus.
Weiss SR, Navas-Martin S. Weiss SR, et al. Microbiol Mol Biol Rev. 2005 Dec;69(4):635-64. doi: 10.1128/MMBR.69.4.635-664.2005. Microbiol Mol Biol Rev. 2005. PMID: 16339739 Free PMC article. Review.
This coronavirus family consists of pathogens of many animal species and of humans, including the recently isolated severe acute respiratory syndrome coronavirus (SARS-CoV). ...The coronavirus part covers (i) a description of a group of coronaviruses a …
This coronavirus family consists of pathogens of many animal species and of humans, including the recently isolated severe acute resp …
The origins of SARS-CoV-2: A critical review.
Holmes EC, Goldstein SA, Rasmussen AL, Robertson DL, Crits-Christoph A, Wertheim JO, Anthony SJ, Barclay WS, Boni MF, Doherty PC, Farrar J, Geoghegan JL, Jiang X, Leibowitz JL, Neil SJD, Skern T, Weiss SR, Worobey M, Andersen KG, Garry RF, Rambaut A. Holmes EC, et al. Among authors: weiss sr. Cell. 2021 Sep 16;184(19):4848-4856. doi: 10.1016/j.cell.2021.08.017. Epub 2021 Aug 19. Cell. 2021. PMID: 34480864 Free PMC article. Review.
Since the first reports of a novel severe acute respiratory syndrome (SARS)-like coronavirus in December 2019 in Wuhan, China, there has been intense interest in understanding how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in the human popu …
Since the first reports of a novel severe acute respiratory syndrome (SARS)-like coronavirus in December 2019 in Wuhan, China, there …
Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children.
Lee D, Le Pen J, Yatim A, Dong B, Aquino Y, Ogishi M, Pescarmona R, Talouarn E, Rinchai D, Zhang P, Perret M, Liu Z, Jordan I, Elmas Bozdemir S, Bayhan GI, Beaufils C, Bizien L, Bisiaux A, Lei W, Hasan M, Chen J, Gaughan C, Asthana A, Libri V, Luna JM, Jaffré F, Hoffmann HH, Michailidis E, Moreews M, Seeleuthner Y, Bilguvar K, Mane S, Flores C, Zhang Y, Arias AA, Bailey R, Schlüter A, Milisavljevic B, Bigio B, Le Voyer T, Materna M, Gervais A, Moncada-Velez M, Pala F, Lazarov T, Levy R, Neehus AL, Rosain J, Peel J, Chan YH, Morin MP, Pino-Ramirez RM, Belkaya S, Lorenzo L, Anton J, Delafontaine S, Toubiana J, Bajolle F, Fumadó V, DeDiego ML, Fidouh N, Rozenberg F, Pérez-Tur J, Chen S, Evans T, Geissmann F, Lebon P, Weiss SR, Bonnet D, Duval X; CoV-Contact Cohort§; COVID Human Genetic Effort¶; Pan-Hammarström Q, Planas AM, Meyts I, Haerynck F, Pujol A, Sancho-Shimizu V, Dalgard CL, Bustamante J, Puel A, Boisson-Dupuis S, Boisson B, Maniatis T, Zhang Q, Bastard P, Notarangelo L, Béziat V, Perez de Diego R, Rodriguez-Gallego C, Su HC, Lifton RP, Jouanguy E, Cobat A, Alsina L, Keles S, Haddad E, Abel L, Belot A, Quintana-Murci L, Rice CM, Silverman RH, Zhang SY, Casanova JL. Lee D, et al. Among authors: weiss sr. Science. 2023 Feb 10;379(6632):eabo3627. doi: 10.1126/science.abo3627. Epub 2023 Feb 10. Science. 2023. PMID: 36538032 Free PMC article.
Monocytic cell lines and primary myeloid cells with OAS1, OAS2, or RNase L deficiencies produce excessive amounts of inflammatory cytokines upon dsRNA or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) stimulation. Exogenous 2-5A suppresses cytokine production …
Monocytic cell lines and primary myeloid cells with OAS1, OAS2, or RNase L deficiencies produce excessive amounts of inflammatory cytokines …
SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry.
Kee J, Thudium S, Renner DM, Glastad K, Palozola K, Zhang Z, Li Y, Lan Y, Cesare J, Poleshko A, Kiseleva AA, Truitt R, Cardenas-Diaz FL, Zhang X, Xie X, Kotton DN, Alysandratos KD, Epstein JA, Shi PY, Yang W, Morrisey E, Garcia BA, Berger SL, Weiss SR, Korb E. Kee J, et al. Among authors: weiss sr. Nature. 2022 Oct;610(7931):381-388. doi: 10.1038/s41586-022-05282-z. Epub 2022 Oct 5. Nature. 2022. PMID: 36198800 Free PMC article.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged at the end of 2019 and caused the devastating global pandemic of coronavirus disease 2019 (COVID-19), in part because of its ability to effectively suppress host cell responses(1-3). ...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged at the end of 2019 and caused the devastating global pandemic of …
Coronavirus pathogenesis.
Weiss SR, Leibowitz JL. Weiss SR, et al. Adv Virus Res. 2011;81:85-164. doi: 10.1016/B978-0-12-385885-6.00009-2. Adv Virus Res. 2011. PMID: 22094080 Free PMC article. Review.
Coronaviruses infect many species of animals including humans, causing acute and chronic diseases. This review focuses primarily on the pathogenesis of murine coronavirus mouse hepatitis virus (MHV) and severe acute respiratory coronavirus (SARS-CoV). ...
Coronaviruses infect many species of animals including humans, causing acute and chronic diseases. This review focuses primarily on t …
Specificity and Mechanism of Coronavirus, Rotavirus, and Mammalian Two-Histidine Phosphoesterases That Antagonize Antiviral Innate Immunity.
Asthana A, Gaughan C, Dong B, Weiss SR, Silverman RH. Asthana A, et al. Among authors: weiss sr. mBio. 2021 Aug 31;12(4):e0178121. doi: 10.1128/mBio.01781-21. Epub 2021 Aug 10. mBio. 2021. PMID: 34372695 Free PMC article.
Here, we probed the evolutionary relationships and biochemical activities of two-histidine phosphoesterases (2H-PEs) that allow some coronaviruses and rotaviruses to counteract antiviral innate immunity. ...These findings may eventually lead to pharmacological strategies f …
Here, we probed the evolutionary relationships and biochemical activities of two-histidine phosphoesterases (2H-PEs) that allow some coro …
Origins and pathogenesis of Middle East respiratory syndrome-associated coronavirus: recent advances.
Goldstein SA, Weiss SR. Goldstein SA, et al. Among authors: weiss sr. F1000Res. 2017 Sep 1;6:1628. doi: 10.12688/f1000research.11827.1. eCollection 2017. F1000Res. 2017. PMID: 29026532 Free PMC article. Review.
Middle East respiratory syndrome-associated coronavirus (MERS-CoV) has been a significant research focus since its discovery in 2012. ...
Middle East respiratory syndrome-associated coronavirus (MERS-CoV) has been a significant research focus since its discovery in 2012. …
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling.
Otter CJ, Bracci N, Parenti NA, Ye C, Tan LH, Asthana A, Pfannenstiel JJ, Jackson N, Fehr AR, Silverman RH, Cohen NA, Martinez-Sobrido L, Weiss SR. Otter CJ, et al. Among authors: weiss sr. bioRxiv [Preprint]. 2023 Nov 15:2023.11.15.566945. doi: 10.1101/2023.11.15.566945. bioRxiv. 2023. PMID: 38014074 Free PMC article. Updated. Preprint.
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 has caused millions of deaths since emerging in 2019. ...The conserved nonstructural protein 15 (nsp15) endoribonuclease (EndoU) limits activation of double-stranded (ds)RNA-induced pathways, including interferon ( …
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 has caused millions of deaths since emerging in 2019. ...The conserved non …
Physiologic RNA targets and refined sequence specificity of coronavirus EndoU.
Ancar R, Li Y, Kindler E, Cooper DA, Ransom M, Thiel V, Weiss SR, Hesselberth JR, Barton DJ. Ancar R, et al. Among authors: weiss sr. RNA. 2020 Dec;26(12):1976-1999. doi: 10.1261/rna.076604.120. Epub 2020 Sep 28. RNA. 2020. PMID: 32989044 Free PMC article.
Coronavirus EndoU inhibits dsRNA-activated antiviral responses; however, the physiologic RNA substrates of EndoU are unknown. ...The physiologic targets of EndoU are viral RNA templates required for negative-strand RNA synthesis and dsRNA accumulation. Coronavirus E …
Coronavirus EndoU inhibits dsRNA-activated antiviral responses; however, the physiologic RNA substrates of EndoU are unknown. ...The …
Infection of primary nasal epithelial cells differentiates among lethal and seasonal human coronaviruses.
Otter CJ, Fausto A, Tan LH, Khosla AS, Cohen NA, Weiss SR. Otter CJ, et al. Among authors: weiss sr. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15):e2218083120. doi: 10.1073/pnas.2218083120. Epub 2023 Apr 6. Proc Natl Acad Sci U S A. 2023. PMID: 37023127 Free PMC article.
The nasal epithelium is the initial entry portal and primary barrier to infection by all human coronaviruses (HCoVs). We utilize primary human nasal epithelial cells grown at air-liquid interface, which recapitulate the heterogeneous cellular population as well as mucocili …
The nasal epithelium is the initial entry portal and primary barrier to infection by all human coronaviruses (HCoVs). We utilize prim …
194 results