Loretz C - Search Results

1

In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries.

Utkarsh D, Loretz C, Li AP. Utkarsh D, et al. Among authors: loretz c. Chem Biol Interact. 2016 Aug 5;255:12-22. doi: 10.1016/j.cbi.2015.12.013. Epub 2015 Dec 21. Chem Biol Interact. 2016. PMID: 26718876

2

A Novel In Vitro Experimental System for the Evaluation of Drug Metabolism: Cofactor-Supplemented Permeabilized Cryopreserved Human Hepatocytes (MetMax Cryopreserved Human Hepatocytes).

Li AP, Ho MD, Amaral K, Loretz C. Li AP, et al. Among authors: loretz c. Drug Metab Dispos. 2018 Nov;46(11):1608-1616. doi: 10.1124/dmd.117.079657. Epub 2018 Jan 23. Drug Metab Dispos. 2018. PMID: 29363498

3

Cryopreserved Human Intestinal Mucosal Epithelium: A Novel In Vitro Experimental System for the Evaluation of Enteric Drug Metabolism, Cytochrome P450 Induction, and Enterotoxicity.

Li AP, Alam N, Amaral K, Ho MD, Loretz C, Mitchell W, Yang Q. Li AP, et al. Among authors: loretz c. Drug Metab Dispos. 2018 Nov;46(11):1562-1571. doi: 10.1124/dmd.118.082875. Epub 2018 Jul 13. Drug Metab Dispos. 2018. PMID: 30006371

4

Application of Cryopreserved Human Intestinal Mucosa and Cryopreserved Human Enterocytes in the Evaluation of Herb-Drug Interactions: Evaluation of CYP3A Inhibitory Potential of Grapefruit Juice and Commercial Formulations of Twenty-Nine Herbal Supplements.

Loretz C, Ho MD, Alam N, Mitchell W, Li AP. Loretz C, et al. Drug Metab Dispos. 2020 Oct;48(10):1084-1091. doi: 10.1124/dmd.120.000033. Epub 2020 Jul 27. Drug Metab Dispos. 2020. PMID: 32719085

5

Podocyte injury at young age causes premature senescence and worsens glomerular aging.

Veloso Pereira BM, Zeng Y, Maggiore JC, Schweickart RA, Eng DG, Kaverina N, McKinzie SR, Chang A, Loretz CJ, Thieme K, Hukriede NA, Pippin JW, Wessely O, Shankland SJ. Veloso Pereira BM, et al. Among authors: loretz cj. Am J Physiol Renal Physiol. 2024 Jan 1;326(1):F120-F134. doi: 10.1152/ajprenal.00261.2023. Epub 2023 Oct 19. Am J Physiol Renal Physiol. 2024. PMID: 37855038

6

Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span.

Kaverina N, Schweickart RA, Chan GC, Maggiore JC, Eng DG, Zeng Y, McKinzie SR, Perry HS, Ali A, O'Connor C, Pereira BMV, Theberge AB, Vaughan JC, Loretz CJ, Chang A, Hukriede NA, Bitzer M, Pippin JW, Wessely O, Shankland SJ. Kaverina N, et al. Among authors: loretz cj. Aging (Albany NY). 2023 Jul 23;15(14):6658-6689. doi: 10.18632/aging.204897. Epub 2023 Jul 23. Aging (Albany NY). 2023. PMID: 37487005 Free PMC article.

7

Upregulated PD-1 signaling antagonizes glomerular health in aged kidneys and disease.

Pippin JW, Kaverina N, Wang Y, Eng DG, Zeng Y, Tran U, Loretz CJ, Chang A, Akilesh S, Poudel C, Perry HS, O'Connor C, Vaughan JC, Bitzer M, Wessely O, Shankland SJ. Pippin JW, et al. Among authors: loretz cj. J Clin Invest. 2022 Aug 15;132(16):e156250. doi: 10.1172/JCI156250. J Clin Invest. 2022. PMID: 35968783 Free PMC article.

8

Global transcriptomic changes occur in aged mouse podocytes.

Wang Y, Eng DG, Kaverina NV, Loretz CJ, Koirala A, Akilesh S, Pippin JW, Shankland SJ. Wang Y, et al. Among authors: loretz cj. Kidney Int. 2020 Nov;98(5):1160-1173. doi: 10.1016/j.kint.2020.05.052. Epub 2020 Jun 25. Kidney Int. 2020. PMID: 32592814 Free PMC article.

9

Low dose aspirin is associated with plasma chemerin levels and may reduce adipose tissue inflammation.

Herová M, Schmid M, Gemperle C, Loretz C, Hersberger M. Herová M, et al. Among authors: loretz c. Atherosclerosis. 2014 Aug;235(2):256-62. doi: 10.1016/j.atherosclerosis.2014.05.912. Epub 2014 May 15. Atherosclerosis. 2014. PMID: 24880897

10

Morpholino oligonucleotide knockdown of the extracellular calcium-sensing receptor impairs early skeletal development in zebrafish.

Herberger AL, Loretz CA. Herberger AL, et al. Among authors: loretz ca. Comp Biochem Physiol A Mol Integr Physiol. 2013 Nov;166(3):470-81. doi: 10.1016/j.cbpa.2013.07.027. Epub 2013 Aug 1. Comp Biochem Physiol A Mol Integr Physiol. 2013. PMID: 23911792

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