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Direct production of ivermectin-like drugs after domain exchange in the avermectin polyketide synthase of Streptomyces avermitilis ATCC31272.
Org Biomol Chem. 2003 Aug 21;1(16):2840-7. doi: 10.1039/b304022d.
Org Biomol Chem. 2003.
PMID: 12968333
Rapamycin biosynthesis: Elucidation of gene product function.
Gregory MA, Hong H, Lill RE, Gaisser S, Petkovic H, Low L, Sheehan LS, Carletti I, Ready SJ, Ward MJ, Kaja AL, Weston AJ, Challis IR, Leadlay PF, Martin CJ, Wilkinson B, Sheridan RM.
Gregory MA, et al. Among authors: kaja al.
Org Biomol Chem. 2006 Oct 7;4(19):3565-8. doi: 10.1039/b608813a. Epub 2006 Aug 22.
Org Biomol Chem. 2006.
PMID: 16990929
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Engineered biosynthesis of hybrid macrolide polyketides containing D-angolosamine and D-mycaminose moieties.
Schell U, Haydock SF, Kaja AL, Carletti I, Lill RE, Read E, Sheehan LS, Low L, Fernandez MJ, Grolle F, McArthur HA, Sheridan RM, Leadlay PF, Wilkinson B, Gaisser S.
Schell U, et al. Among authors: kaja al.
Org Biomol Chem. 2008 Sep 21;6(18):3315-27. doi: 10.1039/b807914e. Epub 2008 Jul 28.
Org Biomol Chem. 2008.
PMID: 18802638
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Engineering of the spinosyn PKS: directing starter unit incorporation.
Sheehan LS, Lill RE, Wilkinson B, Sheridan RM, Vousden WA, Kaja AL, Crouse GD, Gifford J, Graupner PR, Karr L, Lewer P, Sparks TC, Leadlay PF, Waldron C, Martin CJ.
Sheehan LS, et al. Among authors: kaja al.
J Nat Prod. 2006 Dec;69(12):1702-10. doi: 10.1021/np0602517.
J Nat Prod. 2006.
PMID: 17190446
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Separation of anti-angiogenic and cytotoxic activities of borrelidin by modification at the C17 side chain.
Wilkinson B, Gregory MA, Moss SJ, Carletti I, Sheridan RM, Kaja A, Ward M, Olano C, Mendez C, Salas JA, Leadlay PF, vanGinckel R, Zhang MQ.
Wilkinson B, et al.
Bioorg Med Chem Lett. 2006 Nov 15;16(22):5814-7. doi: 10.1016/j.bmcl.2006.08.073. Epub 2006 Sep 8.
Bioorg Med Chem Lett. 2006.
PMID: 16962775
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