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Phosphorylated FTY720 promotes astrocyte migration through sphingosine-1-phosphate receptors.
J Neurochem. 2007 Aug;102(4):1151-61. doi: 10.1111/j.1471-4159.2007.04629.x.
J Neurochem. 2007.
PMID: 17488279
Free article.
Dose and Schedule Determine Distinct Molecular Mechanisms Underlying the Efficacy of the p53-MDM2 Inhibitor HDM201.
Jeay S, Ferretti S, Holzer P, Fuchs J, Chapeau EA, Wartmann M, Sterker D, Romanet V, Murakami M, Kerr G, Durand EY, Gaulis S, Cortes-Cros M, Ruetz S, Stachyra TM, Kallen J, Furet P, Würthner J, Guerreiro N, Halilovic E, Jullion A, Kauffmann A, Kuriakose E, Wiesmann M, Jensen MR, Hofmann F, Sellers WR.
Jeay S, et al. Among authors: cortes cros m.
Cancer Res. 2018 Nov 1;78(21):6257-6267. doi: 10.1158/0008-5472.CAN-18-0338. Epub 2018 Aug 22.
Cancer Res. 2018.
PMID: 30135191
Clinical Trial.
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The path to oncology drug target validation: an industry perspective.
Cortés-Cros M, Schmelzle T, Stucke VM, Hofmann F.
Cortés-Cros M, et al.
Methods Mol Biol. 2013;986:3-13. doi: 10.1007/978-1-62703-311-4_1.
Methods Mol Biol. 2013.
PMID: 23436402
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Dual inhibition of MDM2 and MDM4 in virus-positive Merkel cell carcinoma enhances the p53 response.
Park DE, Cheng J, Berrios C, Montero J, Cortés-Cros M, Ferretti S, Arora R, Tillgren ML, Gokhale PC, DeCaprio JA.
Park DE, et al. Among authors: cortes cros m.
Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):1027-1032. doi: 10.1073/pnas.1818798116. Epub 2018 Dec 31.
Proc Natl Acad Sci U S A. 2019.
PMID: 30598450
Free PMC article.
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M2 isoform of pyruvate kinase is dispensable for tumor maintenance and growth.
Cortés-Cros M, Hemmerlin C, Ferretti S, Zhang J, Gounarides JS, Yin H, Muller A, Haberkorn A, Chene P, Sellers WR, Hofmann F.
Cortés-Cros M, et al.
Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):489-94. doi: 10.1073/pnas.1212780110. Epub 2012 Dec 24.
Proc Natl Acad Sci U S A. 2013.
PMID: 23267074
Free PMC article.
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Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening.
McDonald ER 3rd, de Weck A, Schlabach MR, Billy E, Mavrakis KJ, Hoffman GR, Belur D, Castelletti D, Frias E, Gampa K, Golji J, Kao I, Li L, Megel P, Perkins TA, Ramadan N, Ruddy DA, Silver SJ, Sovath S, Stump M, Weber O, Widmer R, Yu J, Yu K, Yue Y, Abramowski D, Ackley E, Barrett R, Berger J, Bernard JL, Billig R, Brachmann SM, Buxton F, Caothien R, Caushi JX, Chung FS, Cortés-Cros M, deBeaumont RS, Delaunay C, Desplat A, Duong W, Dwoske DA, Eldridge RS, Farsidjani A, Feng F, Feng J, Flemming D, Forrester W, Galli GG, Gao Z, Gauter F, Gibaja V, Haas K, Hattenberger M, Hood T, Hurov KE, Jagani Z, Jenal M, Johnson JA, Jones MD, Kapoor A, Korn J, Liu J, Liu Q, Liu S, Liu Y, Loo AT, Macchi KJ, Martin T, McAllister G, Meyer A, Mollé S, Pagliarini RA, Phadke T, Repko B, Schouwey T, Shanahan F, Shen Q, Stamm C, Stephan C, Stucke VM, Tiedt R, Varadarajan M, Venkatesan K, Vitari AC, Wallroth M, Weiler J, Zhang J, Mickanin C, Myer VE, Porter JA, Lai A, Bitter H, Lees E, Keen N, Kauffmann A, Stegmeier F, Hofmann F, Schmelzle T, Sellers WR.
McDonald ER 3rd, et al. Among authors: cortes cros m.
Cell. 2017 Jul 27;170(3):577-592.e10. doi: 10.1016/j.cell.2017.07.005.
Cell. 2017.
PMID: 28753431
Free article.
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Challenges for the Discovery of Non-Covalent WRN Helicase Inhibitors.
Heuser A, Abdul Rahman W, Bechter E, Blank J, Buhr S, Erdmann D, Fontana P, Mermet-Meillon F, Meyerhofer M, Strang R, Schrapp M, Zimmermann C, Cortes-Cros M, Möbitz H, Hamon J.
Heuser A, et al. Among authors: cortes cros m.
ChemMedChem. 2024 Apr 16;19(8):e202300613. doi: 10.1002/cmdc.202300613. Epub 2024 Mar 7.
ChemMedChem. 2024.
PMID: 38334957
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Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers.
Ferretti S, Hamon J, de Kanter R, Scheufler C, Andraos-Rey R, Barbe S, Bechter E, Blank J, Bordas V, Dammassa E, Decker A, Di Nanni N, Dourdoigne M, Gavioli E, Hattenberger M, Heuser A, Hemmerlin C, Hinrichs J, Kerr G, Laborde L, Jaco I, Núñez EJ, Martus HJ, Quadt C, Reschke M, Romanet V, Schaeffer F, Schoepfer J, Schrapp M, Strang R, Voshol H, Wartmann M, Welly S, Zécri F, Hofmann F, Möbitz H, Cortés-Cros M.
Ferretti S, et al. Among authors: cortes cros m.
Nature. 2024 May;629(8011):443-449. doi: 10.1038/s41586-024-07350-y. Epub 2024 Apr 24.
Nature. 2024.
PMID: 38658754
Free PMC article.
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