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Page 1
Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin.
Brines M, Patel NS, Villa P, Brines C, Mennini T, De Paola M, Erbayraktar Z, Erbayraktar S, Sepodes B, Thiemermann C, Ghezzi P, Yamin M, Hand CC, Xie QW, Coleman T, Cerami A. Brines M, et al. Among authors: ghezzi p. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10925-30. doi: 10.1073/pnas.0805594105. Epub 2008 Aug 1. Proc Natl Acad Sci U S A. 2008. PMID: 18676614 Free PMC article.
Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo.
Erbayraktar S, Grasso G, Sfacteria A, Xie QW, Coleman T, Kreilgaard M, Torup L, Sager T, Erbayraktar Z, Gokmen N, Yilmaz O, Ghezzi P, Villa P, Fratelli M, Casagrande S, Leist M, Helboe L, Gerwein J, Christensen S, Geist MA, Pedersen LØ, Cerami-Hand C, Wuerth JP, Cerami A, Brines M. Erbayraktar S, et al. Among authors: ghezzi p. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6741-6. doi: 10.1073/pnas.1031753100. Epub 2003 May 13. Proc Natl Acad Sci U S A. 2003. PMID: 12746497 Free PMC article.
Erythropoietin mediates tissue protection through an erythropoietin and common beta-subunit heteroreceptor.
Brines M, Grasso G, Fiordaliso F, Sfacteria A, Ghezzi P, Fratelli M, Latini R, Xie QW, Smart J, Su-Rick CJ, Pobre E, Diaz D, Gomez D, Hand C, Coleman T, Cerami A. Brines M, et al. Among authors: ghezzi p. Proc Natl Acad Sci U S A. 2004 Oct 12;101(41):14907-12. doi: 10.1073/pnas.0406491101. Epub 2004 Sep 29. Proc Natl Acad Sci U S A. 2004. PMID: 15456912 Free PMC article.
A nonerythropoietic derivative of erythropoietin protects the myocardium from ischemia-reperfusion injury.
Fiordaliso F, Chimenti S, Staszewsky L, Bai A, Carlo E, Cuccovillo I, Doni M, Mengozzi M, Tonelli R, Ghezzi P, Coleman T, Brines M, Cerami A, Latini R. Fiordaliso F, et al. Among authors: ghezzi p. Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2046-51. doi: 10.1073/pnas.0409329102. Epub 2005 Jan 25. Proc Natl Acad Sci U S A. 2005. PMID: 15671158 Free PMC article.
Cytoprotective doses of erythropoietin or carbamylated erythropoietin have markedly different procoagulant and vasoactive activities.
Coleman TR, Westenfelder C, Tögel FE, Yang Y, Hu Z, Swenson L, Leuvenink HG, Ploeg RJ, d'Uscio LV, Katusic ZS, Ghezzi P, Zanetti A, Kaushansky K, Fox NE, Cerami A, Brines M. Coleman TR, et al. Among authors: ghezzi p. Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5965-70. doi: 10.1073/pnas.0601377103. Epub 2006 Apr 3. Proc Natl Acad Sci U S A. 2006. PMID: 16585502 Free PMC article.
Erythropoietin-induced changes in brain gene expression reveal induction of synaptic plasticity genes in experimental stroke.
Mengozzi M, Cervellini I, Villa P, Erbayraktar Z, Gökmen N, Yilmaz O, Erbayraktar S, Manohasandra M, Van Hummelen P, Vandenabeele P, Chernajovsky Y, Annenkov A, Ghezzi P. Mengozzi M, et al. Among authors: ghezzi p. Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9617-22. doi: 10.1073/pnas.1200554109. Epub 2012 May 29. Proc Natl Acad Sci U S A. 2012. PMID: 22645329 Free PMC article.
Erythropoietin both protects from and reverses experimental diabetic neuropathy.
Bianchi R, Buyukakilli B, Brines M, Savino C, Cavaletti G, Oggioni N, Lauria G, Borgna M, Lombardi R, Cimen B, Comelekoglu U, Kanik A, Tataroglu C, Cerami A, Ghezzi P. Bianchi R, et al. Among authors: ghezzi p. Proc Natl Acad Sci U S A. 2004 Jan 20;101(3):823-8. doi: 10.1073/pnas.0307823100. Epub 2004 Jan 12. Proc Natl Acad Sci U S A. 2004. PMID: 14718663 Free PMC article.
Derivatives of erythropoietin that are tissue protective but not erythropoietic.
Leist M, Ghezzi P, Grasso G, Bianchi R, Villa P, Fratelli M, Savino C, Bianchi M, Nielsen J, Gerwien J, Kallunki P, Larsen AK, Helboe L, Christensen S, Pedersen LO, Nielsen M, Torup L, Sager T, Sfacteria A, Erbayraktar S, Erbayraktar Z, Gokmen N, Yilmaz O, Cerami-Hand C, Xie QW, Coleman T, Cerami A, Brines M. Leist M, et al. Among authors: ghezzi p. Science. 2004 Jul 9;305(5681):239-42. doi: 10.1126/science.1098313. Science. 2004. PMID: 15247477
436 results