Dwek RA - Search Results

1

N-Butyldeoxynojirimycin is a broadly effective anti-HIV therapy significantly enhanced by targeted liposome delivery.

Pollock S, Dwek RA, Burton DR, Zitzmann N. Pollock S, et al. Among authors: dwek ra. AIDS. 2008 Oct 1;22(15):1961-9. doi: 10.1097/QAD.0b013e32830efd96. AIDS. 2008. PMID: 18753929

2

Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.

Dunlop DC, Ulrich A, Appelmelk BJ, Burton DR, Dwek RA, Zitzmann N, Scanlan CN. Dunlop DC, et al. Among authors: dwek ra. AIDS. 2008 Oct 18;22(16):2214-7. doi: 10.1097/QAD.0b013e328314b5df. AIDS. 2008. PMID: 18832887

3

Polyunsaturated liposomes are antiviral against hepatitis B and C viruses and HIV by decreasing cholesterol levels in infected cells.

Pollock S, Nichita NB, Böhmer A, Radulescu C, Dwek RA, Zitzmann N. Pollock S, et al. Among authors: dwek ra. Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17176-81. doi: 10.1073/pnas.1009445107. Epub 2010 Sep 20. Proc Natl Acad Sci U S A. 2010. PMID: 20855621 Free PMC article.

4

Liposome-mediated delivery of iminosugars enhances efficacy against dengue virus in vivo.

Miller JL, Lachica R, Sayce AC, Williams JP, Bapat M, Dwek R, Beatty PR, Harris E, Zitzmann N. Miller JL, et al. Antimicrob Agents Chemother. 2012 Dec;56(12):6379-86. doi: 10.1128/AAC.01554-12. Epub 2012 Oct 15. Antimicrob Agents Chemother. 2012. PMID: 23070155 Free PMC article.

5

Targeting glycosylation as a therapeutic approach.

Dwek RA, Butters TD, Platt FM, Zitzmann N. Dwek RA, et al. Nat Rev Drug Discov. 2002 Jan;1(1):65-75. doi: 10.1038/nrd708. Nat Rev Drug Discov. 2002. PMID: 12119611 Review.

6

Exploiting the defensive sugars of HIV-1 for drug and vaccine design.

Scanlan CN, Offer J, Zitzmann N, Dwek RA. Scanlan CN, et al. Among authors: dwek ra. Nature. 2007 Apr 26;446(7139):1038-45. doi: 10.1038/nature05818. Nature. 2007. PMID: 17460665 Review.

7

Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralising, HIV-1 specific antibody.

Scanlan CN, Ritchie GE, Baruah K, Crispin M, Harvey DJ, Singer BB, Lucka L, Wormald MR, Wentworth P Jr, Zitzmann N, Rudd PM, Burton DR, Dwek RA. Scanlan CN, et al. Among authors: dwek ra. J Mol Biol. 2007 Sep 7;372(1):16-22. doi: 10.1016/j.jmb.2007.06.027. Epub 2007 Jun 16. J Mol Biol. 2007. PMID: 17631311

8

Iminosugars in combination with interferon and ribavirin permanently eradicate noncytopathic bovine viral diarrhea virus from persistently infected cells.

Woodhouse SD, Smith C, Michelet M, Branza-Nichita N, Hussey M, Dwek RA, Zitzmann N. Woodhouse SD, et al. Among authors: dwek ra. Antimicrob Agents Chemother. 2008 May;52(5):1820-8. doi: 10.1128/AAC.01181-07. Epub 2008 Mar 3. Antimicrob Agents Chemother. 2008. PMID: 18316522 Free PMC article.

9

Uptake and trafficking of liposomes to the endoplasmic reticulum.

Pollock S, Antrobus R, Newton L, Kampa B, Rossa J, Latham S, Nichita NB, Dwek RA, Zitzmann N. Pollock S, et al. Among authors: dwek ra. FASEB J. 2010 Jun;24(6):1866-78. doi: 10.1096/fj.09-145755. Epub 2010 Jan 22. FASEB J. 2010. PMID: 20097877

10

Minimal In Vivo Efficacy of Iminosugars in a Lethal Ebola Virus Guinea Pig Model.

Miller JL, Spiro SG, Dowall SD, Taylor I, Rule A, Alonzi DS, Sayce AC, Wright E, Bentley EM, Thom R, Hall G, Dwek RA, Hewson R, Zitzmann N. Miller JL, et al. Among authors: dwek ra. PLoS One. 2016 Nov 23;11(11):e0167018. doi: 10.1371/journal.pone.0167018. eCollection 2016. PLoS One. 2016. PMID: 27880800 Free PMC article.

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