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The pannexin 1 channel activates the inflammasome in neurons and astrocytes.
Silverman WR, de Rivero Vaccari JP, Locovei S, Qiu F, Carlsson SK, Scemes E, Keane RW, Dahl G. Silverman WR, et al. Among authors: dahl g. J Biol Chem. 2009 Jul 3;284(27):18143-51. doi: 10.1074/jbc.M109.004804. Epub 2009 May 5. J Biol Chem. 2009. PMID: 19416975 Free PMC article.
Pyroptotic neuronal cell death mediated by the AIM2 inflammasome.
Adamczak SE, de Rivero Vaccari JP, Dale G, Brand FJ 3rd, Nonner D, Bullock MR, Dahl GP, Dietrich WD, Keane RW. Adamczak SE, et al. Among authors: dahl gp. J Cereb Blood Flow Metab. 2014 Apr;34(4):621-9. doi: 10.1038/jcbfm.2013.236. Epub 2014 Jan 8. J Cereb Blood Flow Metab. 2014. PMID: 24398937 Free PMC article.
Pannexin 1 in erythrocytes: function without a gap.
Locovei S, Bao L, Dahl G. Locovei S, et al. Among authors: dahl g. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7655-9. doi: 10.1073/pnas.0601037103. Epub 2006 May 8. Proc Natl Acad Sci U S A. 2006. PMID: 16682648 Free PMC article.
Probenecid, a gout remedy, inhibits pannexin 1 channels.
Silverman W, Locovei S, Dahl G. Silverman W, et al. Among authors: dahl g. Am J Physiol Cell Physiol. 2008 Sep;295(3):C761-7. doi: 10.1152/ajpcell.00227.2008. Epub 2008 Jul 2. Am J Physiol Cell Physiol. 2008. PMID: 18596212 Free PMC article.
Pannexin: from discovery to bedside in 11±4 years?
Dahl G, Keane RW. Dahl G, et al. Brain Res. 2012 Dec 3;1487:150-9. doi: 10.1016/j.brainres.2012.04.058. Epub 2012 Jul 4. Brain Res. 2012. PMID: 22771709 Free PMC article. Review.
559 results