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The role of oxidative damage and stress in aging.
Bokov A, Chaudhuri A, Richardson A. Bokov A, et al. Mech Ageing Dev. 2004 Oct-Nov;125(10-11):811-26. doi: 10.1016/j.mad.2004.07.009. Mech Ageing Dev. 2004. PMID: 15541775 Review.
Long-lived ames dwarf mice are resistant to chemical stressors.
Bokov AF, Lindsey ML, Khodr C, Sabia MR, Richardson A. Bokov AF, et al. J Gerontol A Biol Sci Med Sci. 2009 Aug;64(8):819-27. doi: 10.1093/gerona/glp052. Epub 2009 May 4. J Gerontol A Biol Sci Med Sci. 2009. PMID: 19414510 Free PMC article.
Does reduced IGF-1R signaling in Igf1r+/- mice alter aging?
Bokov AF, Garg N, Ikeno Y, Thakur S, Musi N, DeFronzo RA, Zhang N, Erickson RC, Gelfond J, Hubbard GB, Adamo ML, Richardson A. Bokov AF, et al. PLoS One. 2011;6(11):e26891. doi: 10.1371/journal.pone.0026891. Epub 2011 Nov 23. PLoS One. 2011. PMID: 22132081 Free PMC article.
Is the oxidative stress theory of aging dead?
Pérez VI, Bokov A, Van Remmen H, Mele J, Ran Q, Ikeno Y, Richardson A. Pérez VI, et al. Biochim Biophys Acta. 2009 Oct;1790(10):1005-14. doi: 10.1016/j.bbagen.2009.06.003. Epub 2009 Jun 11. Biochim Biophys Acta. 2009. PMID: 19524016 Free PMC article. Review.
Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity.
Zhang Y, Ikeno Y, Qi W, Chaudhuri A, Li Y, Bokov A, Thorpe SR, Baynes JW, Epstein C, Richardson A, Van Remmen H. Zhang Y, et al. J Gerontol A Biol Sci Med Sci. 2009 Dec;64(12):1212-20. doi: 10.1093/gerona/glp132. Epub 2009 Sep 23. J Gerontol A Biol Sci Med Sci. 2009. PMID: 19776219 Free PMC article.
Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice.
Pérez VI, Cortez LA, Lew CM, Rodriguez M, Webb CR, Van Remmen H, Chaudhuri A, Qi W, Lee S, Bokov A, Fok W, Jones D, Richardson A, Yodoi J, Zhang Y, Tominaga K, Hubbard GB, Ikeno Y. Pérez VI, et al. J Gerontol A Biol Sci Med Sci. 2011 Dec;66(12):1286-99. doi: 10.1093/gerona/glr125. Epub 2011 Aug 26. J Gerontol A Biol Sci Med Sci. 2011. PMID: 21873593 Free PMC article.
Dietary restriction attenuates the accelerated aging phenotype of Sod1(-/-) mice.
Zhang Y, Ikeno Y, Bokov A, Gelfond J, Jaramillo C, Zhang HM, Liu Y, Qi W, Hubbard G, Richardson A, Van Remmen H. Zhang Y, et al. Free Radic Biol Med. 2013 Jul;60:300-6. doi: 10.1016/j.freeradbiomed.2013.02.026. Epub 2013 Feb 28. Free Radic Biol Med. 2013. PMID: 23459073 Free PMC article.
36 results