Blundell MP - Search Results

1

Correction of SCID-X1 using an enhancerless Vav promoter.

Almarza E, Zhang F, Santilli G, Blundell MP, Howe SJ, Thornhill SI, Bueren JA, Thrasher AJ. Almarza E, et al. Among authors: blundell mp. Hum Gene Ther. 2011 Mar;22(3):263-70. doi: 10.1089/hum.2010.119. Epub 2011 Feb 7. Hum Gene Ther. 2011. PMID: 20887212

2

Biochemical correction of X-CGD by a novel chimeric promoter regulating high levels of transgene expression in myeloid cells.

Santilli G, Almarza E, Brendel C, Choi U, Beilin C, Blundell MP, Haria S, Parsley KL, Kinnon C, Malech HL, Bueren JA, Grez M, Thrasher AJ. Santilli G, et al. Among authors: blundell mp. Mol Ther. 2011 Jan;19(1):122-32. doi: 10.1038/mt.2010.226. Epub 2010 Oct 26. Mol Ther. 2011. PMID: 20978475 Free PMC article.

3

Lentiviral vectors transcriptionally targeted to hematopoietic cells by WASP gene proximal promoter sequences.

Martín F, Toscano MG, Blundell M, Frecha C, Srivastava GK, Santamaría M, Thrasher AJ, Molina IJ. Martín F, et al. Gene Ther. 2005 Apr;12(8):715-23. doi: 10.1038/sj.gt.3302457. Gene Ther. 2005. PMID: 15750617

4

A ubiquitous chromatin opening element (UCOE) confers resistance to DNA methylation-mediated silencing of lentiviral vectors.

Zhang F, Frost AR, Blundell MP, Bales O, Antoniou MN, Thrasher AJ. Zhang F, et al. Among authors: blundell mp. Mol Ther. 2010 Sep;18(9):1640-9. doi: 10.1038/mt.2010.132. Epub 2010 Jun 29. Mol Ther. 2010. PMID: 20588258 Free PMC article.

5

Correction of murine SCID-X1 by lentiviral gene therapy using a codon-optimized IL2RG gene and minimal pretransplant conditioning.

Huston MW, van Til NP, Visser TP, Arshad S, Brugman MH, Cattoglio C, Nowrouzi A, Li Y, Schambach A, Schmidt M, Baum C, von Kalle C, Mavilio F, Zhang F, Blundell MP, Thrasher AJ, Verstegen MM, Wagemaker G. Huston MW, et al. Among authors: blundell mp. Mol Ther. 2011 Oct;19(10):1867-77. doi: 10.1038/mt.2011.127. Epub 2011 Jul 12. Mol Ther. 2011. PMID: 21750532 Free PMC article.

6

Lentiviral vectors targeting WASp expression to hematopoietic cells, efficiently transduce and correct cells from WAS patients.

Charrier S, Dupré L, Scaramuzza S, Jeanson-Leh L, Blundell MP, Danos O, Cattaneo F, Aiuti A, Eckenberg R, Thrasher AJ, Roncarolo MG, Galy A. Charrier S, et al. Among authors: blundell mp. Gene Ther. 2007 Mar;14(5):415-28. doi: 10.1038/sj.gt.3302863. Epub 2006 Oct 19. Gene Ther. 2007. PMID: 17051251

7

Cell-specific and efficient expression in mouse and human B cells by a novel hybrid immunoglobulin promoter in a lentiviral vector.

Laurie KL, Blundell MP, Baxendale HE, Howe SJ, Sinclair J, Qasim W, Brunsberg U, Thrasher AJ, Holmdahl R, Gustafsson K. Laurie KL, et al. Among authors: blundell mp. Gene Ther. 2007 Dec;14(23):1623-31. doi: 10.1038/sj.gt.3303021. Epub 2007 Sep 13. Gene Ther. 2007. PMID: 17851547

8

Molecular Evidence of Genome Editing in a Mouse Model of Immunodeficiency.

Abdul-Razak HH, Rocca CJ, Howe SJ, Alonso-Ferrero ME, Wang J, Gabriel R, Bartholomae CC, Gan CHV, Garín MI, Roberts A, Blundell MP, Prakash V, Molina-Estevez FJ, Pantoglou J, Guenechea G, Holmes MC, Gregory PD, Kinnon C, von Kalle C, Schmidt M, Bueren JA, Thrasher AJ, Yáñez-Muñoz RJ. Abdul-Razak HH, et al. Among authors: blundell mp. Sci Rep. 2018 May 29;8(1):8214. doi: 10.1038/s41598-018-26439-9. Sci Rep. 2018. PMID: 29844458 Free PMC article.

9

Generation of functional neutrophils from a mouse model of X-linked chronic granulomatous disorder using induced pluripotent stem cells.

Mukherjee S, Santilli G, Blundell MP, Navarro S, Bueren JA, Thrasher AJ. Mukherjee S, et al. Among authors: blundell mp. PLoS One. 2011 Mar 3;6(3):e17565. doi: 10.1371/journal.pone.0017565. PLoS One. 2011. PMID: 21408614 Free PMC article.

10

Hematopoietic-specific lentiviral vectors circumvent cellular toxicity due to ectopic expression of Wiskott-Aldrich syndrome protein.

Toscano MG, Frecha C, Benabdellah K, Cobo M, Blundell M, Thrasher AJ, García-Olivares E, Molina IJ, Martin F. Toscano MG, et al. Hum Gene Ther. 2008 Feb;19(2):179-97. doi: 10.1089/hum.2007.098. Hum Gene Ther. 2008. PMID: 18240968

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