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BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival.
Gorrini C, Baniasadi PS, Harris IS, Silvester J, Inoue S, Snow B, Joshi PA, Wakeham A, Molyneux SD, Martin B, Bouwman P, Cescon DW, Elia AJ, Winterton-Perks Z, Cruickshank J, Brenner D, Tseng A, Musgrave M, Berman HK, Khokha R, Jonkers J, Mak TW, Gauthier ML. Gorrini C, et al. Among authors: brenner d. J Exp Med. 2013 Jul 29;210(8):1529-44. doi: 10.1084/jem.20121337. Epub 2013 Jul 15. J Exp Med. 2013. PMID: 23857982 Free PMC article.
The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis.
Hao Z, Duncan GS, Su YW, Li WY, Silvester J, Hong C, You H, Brenner D, Gorrini C, Haight J, Wakeham A, You-Ten A, McCracken S, Elia A, Li Q, Detmar J, Jurisicova A, Hobeika E, Reth M, Sheng Y, Lang PA, Ohashi PS, Zhong Q, Wang X, Mak TW. Hao Z, et al. Among authors: brenner d. J Exp Med. 2012 Jan 16;209(1):173-86. doi: 10.1084/jem.20111363. Epub 2012 Jan 2. J Exp Med. 2012. PMID: 22213803 Free PMC article.
Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP(+)/NADPH ratio.
Itsumi M, Inoue S, Elia AJ, Murakami K, Sasaki M, Lind EF, Brenner D, Harris IS, Chio II, Afzal S, Cairns RA, Cescon DW, Elford AR, Ye J, Lang PA, Li WY, Wakeham A, Duncan GS, Haight J, You-Ten A, Snow B, Yamamoto K, Ohashi PS, Mak TW. Itsumi M, et al. Among authors: brenner d. Cell Death Differ. 2015 Nov;22(11):1837-45. doi: 10.1038/cdd.2015.38. Epub 2015 Apr 17. Cell Death Differ. 2015. PMID: 25882048 Free PMC article.
Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression.
Harris IS, Treloar AE, Inoue S, Sasaki M, Gorrini C, Lee KC, Yung KY, Brenner D, Knobbe-Thomsen CB, Cox MA, Elia A, Berger T, Cescon DW, Adeoye A, Brüstle A, Molyneux SD, Mason JM, Li WY, Yamamoto K, Wakeham A, Berman HK, Khokha R, Done SJ, Kavanagh TJ, Lam CW, Mak TW. Harris IS, et al. Among authors: brenner d. Cancer Cell. 2015 Feb 9;27(2):211-22. doi: 10.1016/j.ccell.2014.11.019. Epub 2015 Jan 22. Cancer Cell. 2015. PMID: 25620030 Free article.
TNF and ROS Crosstalk in Inflammation.
Blaser H, Dostert C, Mak TW, Brenner D. Blaser H, et al. Among authors: brenner d. Trends Cell Biol. 2016 Apr;26(4):249-261. doi: 10.1016/j.tcb.2015.12.002. Epub 2016 Jan 12. Trends Cell Biol. 2016. PMID: 26791157 Review.
Mitochondrial cell death effectors.
Brenner D, Mak TW. Brenner D, et al. Curr Opin Cell Biol. 2009 Dec;21(6):871-7. doi: 10.1016/j.ceb.2009.09.004. Epub 2009 Oct 12. Curr Opin Cell Biol. 2009. PMID: 19822411 Review.
Glutathione Primes T Cell Metabolism for Inflammation.
Mak TW, Grusdat M, Duncan GS, Dostert C, Nonnenmacher Y, Cox M, Binsfeld C, Hao Z, Brüstle A, Itsumi M, Jäger C, Chen Y, Pinkenburg O, Camara B, Ollert M, Bindslev-Jensen C, Vasiliou V, Gorrini C, Lang PA, Lohoff M, Harris IS, Hiller K, Brenner D. Mak TW, et al. Among authors: brenner d. Immunity. 2017 Apr 18;46(4):675-689. doi: 10.1016/j.immuni.2017.03.019. Immunity. 2017. PMID: 28423341 Free article.
Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis.
Afzal S, Hao Z, Itsumi M, Abouelkheer Y, Brenner D, Gao Y, Wakeham A, Hong C, Li WY, Sylvester J, Gilani SO, Brüstle A, Haight J, You-Ten AJ, Lin GH, Inoue S, Mak TW. Afzal S, et al. Among authors: brenner d. Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):1119-24. doi: 10.1073/pnas.1423588112. Epub 2015 Jan 12. Proc Natl Acad Sci U S A. 2015. PMID: 25583492 Free PMC article.
2,021 results